Vol. 9, Iss 7 | Metabolites

Article

25 Citations

5,083 Views

17 Pages

Differential Metabolic Reprogramming in Paenibacillus alvei-Primed Sorghum bicolor Seedlings in Response to Fusarium pseudograminearum Infection

René Carlson,
Fidele Tugizimana,
Paul A. Steenkamp,
Ian A. Dubery and
Nico Labuschagne

Metabolites2019, 9(7), 150;https://doi.org/10.3390/metabo9070150

23 July 2019

Metabolic changes in sorghum seedlings in response to Paenibacillus alvei (NAS-6G6)-induced systemic resistance against Fusarium pseudograminearum crown rot were investigated by means of untargeted ultra-high performance liquid chromatography-high de...

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Article

35 Citations

6,733 Views

16 Pages

Metabolomics Analyses in High-Low Feed Efficient Dairy Cows Reveal Novel Biochemical Mechanisms and Predictive Biomarkers

Xiao Wang and
Haja N. Kadarmideen

Metabolites2019, 9(7), 151;https://doi.org/10.3390/metabo9070151

23 July 2019

Residual feed intake (RFI) is designed to estimate net efficiency of feed use, so low RFI animals are considered for selection to reduce feeding costs. However, metabolic profiling of cows and availability of predictive metabolic biomarkers for RFI a...

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Article

37 Citations

5,746 Views

17 Pages

Fibroin Delays Chilling Injury of Postharvest Banana Fruit via Enhanced Antioxidant Capability during Cold Storage

Juan Liu,
Fengjun Li,
Lei Liang,
Yueming Jiang and
Junjia Chen

Metabolites2019, 9(7), 152;https://doi.org/10.3390/metabo9070152

23 July 2019

storage Banana fruit after harvest is susceptible to chilling injury, which is featured by peel browning during cold, and it easily loses its nutrition and economic values. This study investigated the role of fibroin treatment in delaying peel browni...

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Article

2 Citations

5,185 Views

16 Pages

Untargeted Metabolomics Approach Reveals Diverse Responses of Pastinaca Sativa to Ozone and Wounding Stresses

Gianni Galati,
Anthony Gandin,
Yves Jolivet,
Romain Larbat and
Alain Hehn

Metabolites2019, 9(7), 153;https://doi.org/10.3390/metabo9070153

23 July 2019

Stresses such as wounding or atmospheric pollutant exposure have a significant impact on plant fitness. Since it has been widely described that the metabolome directly reflects plant physiological status, a way to assess this impact is to perform a g...

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Article

48 Citations

6,746 Views

18 Pages

The Ruminal Microbiome and Metabolome Alterations Associated with Diet-Induced Milk Fat Depression in Dairy Cows

Hongbo Zeng,
Changzheng Guo,
Daming Sun,
Hossam-eldin Seddik and
Shengyong Mao

Metabolites2019, 9(7), 154;https://doi.org/10.3390/metabo9070154

23 July 2019

Milk fat depression (MFD) syndrome represents a significant drawback to the dairy industry. The aim of this study was to unravel the ruminal metabolome-microbiome interaction in response to diet-induced MFD in dairy cows. Twelve healthy second parity...

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Article

4 Citations

3,492 Views

11 Pages

Pharmacometabolomic Pathway Response of Effective Anticancer Agents on Different Diets in Rats with Induced Mammary Tumors

Zhijun Cao,
Mark Steven Miller,
Ronald A. Lubet,
Clinton J. Grubbs and
Richard D. Beger

Metabolites2019, 9(7), 149;https://doi.org/10.3390/metabo9070149

22 July 2019

Metabolomics is an effective approach to characterize the metabotype which can reflect the influence of genetics, physiological status, and environmental factors such as drug intakes, diet. Diet may change the chemopreventive efficacy of given agents...

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Communication

20 Citations

6,091 Views

11 Pages

Intracellular Staphylococcus aureus Elicits the Production of Host Very Long-Chain Saturated Fatty Acids with Antimicrobial Activity

Natalia Bravo-Santano,
James K. Ellis,
Yolanda Calle,
Hector C. Keun,
Volker Behrends and
Michal Letek

Metabolites2019, 9(7), 148;https://doi.org/10.3390/metabo9070148

20 July 2019

As a facultative intracellular pathogen, Staphylococcus aureus is able to invade and proliferate within many types of mammalian cells. Intracellular bacterial replication relies on host nutrient supplies and, therefore, cell metabolism is closely bou...

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Article

12 Citations

5,232 Views

21 Pages

¹H HR-MAS NMR-Based Metabolomics of Cancer Cells in Response to Treatment with the Diruthenium Trithiolato Complex [(p-MeC₆H₄ⁱPr)₂Ru₂(SC₆H₄-p-Bu^t)₃]⁺ (DiRu-1)

Hedvika Primasová,
Lydia E. H. Paul,
Gaëlle Diserens,
Ester Primasová,
Peter Vermathen,
Martina Vermathen and
Julien Furrer

Metabolites2019, 9(7), 146;https://doi.org/10.3390/metabo9070146

18 July 2019

The trithiolato bridged diruthenium complex DiRu-1 [(p-MeC6H4iPr)2Ru2(SC6H4-p-But)3]+ is highly cytotoxic against various cancer cell lines, but its exact mode of action remains unknown. The present 1H HR-MAS NMR-based metabolomic study was performed...

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Article

14 Citations

5,190 Views

10 Pages

Anion Inhibition Profile of the β-Carbonic Anhydrase from the Opportunist Pathogenic Fungus Malassezia restricta Involved in Dandruff and Seborrheic Dermatitis

Sonia Del Prete,
Andrea Angeli,
Cynthia Ghobril,
Julien Hitce,
Cécile Clavaud,
Xavier Marat,
Claudiu T. Supuran and
Clemente Capasso

Metabolites2019, 9(7), 147;https://doi.org/10.3390/metabo9070147

18 July 2019

Carbonic anhydrases (CAs, EC 4.2.1.1) are ubiquitous metalloenzymes, which catalyze the crucial physiological CO2 hydration/dehydration reaction (CO2 + H2O ⇌ HCO3− + H+) balancing the equilibrium between CO2, H2CO3, HCO3− and CO32−....

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Article

35 Citations

9,797 Views

21 Pages

Metabolomics Analytics Workflow for Epidemiological Research: Perspectives from the Consortium of Metabolomics Studies (COMETS)

Mary C. Playdon,
Amit D. Joshi,
Fred K. Tabung,
Susan Cheng,
Mir Henglin,
Andy Kim,
Tengda Lin,
Eline H. van Roekel,
Jiaqi Huang and
Oana A. Zeleznik
+ 14 authors

Metabolites2019, 9(7), 145;https://doi.org/10.3390/metabo9070145

17 July 2019

The application of metabolomics technology to epidemiological studies is emerging as a new approach to elucidate disease etiology and for biomarker discovery. However, analysis of metabolomics data is complex and there is an urgent need for the stand...

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Metabolites, Volume 9, Issue 7

Articles (33)

Differential Metabolic Reprogramming in Paenibacillus alvei-Primed Sorghum bicolor Seedlings in Response to Fusarium pseudograminearum Infection

Metabolomics Analyses in High-Low Feed Efficient Dairy Cows Reveal Novel Biochemical Mechanisms and Predictive Biomarkers

Fibroin Delays Chilling Injury of Postharvest Banana Fruit via Enhanced Antioxidant Capability during Cold Storage

Untargeted Metabolomics Approach Reveals Diverse Responses of Pastinaca Sativa to Ozone and Wounding Stresses

The Ruminal Microbiome and Metabolome Alterations Associated with Diet-Induced Milk Fat Depression in Dairy Cows

Pharmacometabolomic Pathway Response of Effective Anticancer Agents on Different Diets in Rats with Induced Mammary Tumors

Intracellular Staphylococcus aureus Elicits the Production of Host Very Long-Chain Saturated Fatty Acids with Antimicrobial Activity

¹H HR-MAS NMR-Based Metabolomics of Cancer Cells in Response to Treatment with the Diruthenium Trithiolato Complex [(p-MeC₆H₄ⁱPr)₂Ru₂(SC₆H₄-p-Bu^t)₃]⁺ (DiRu-1)

Anion Inhibition Profile of the β-Carbonic Anhydrase from the Opportunist Pathogenic Fungus Malassezia restricta Involved in Dandruff and Seborrheic Dermatitis

Metabolomics Analytics Workflow for Epidemiological Research: Perspectives from the Consortium of Metabolomics Studies (COMETS)

Metabolites, Volume 9, Issue 7

Articles (33)

Differential Metabolic Reprogramming in Paenibacillus alvei-Primed Sorghum bicolor Seedlings in Response to Fusarium pseudograminearum Infection

Metabolomics Analyses in High-Low Feed Efficient Dairy Cows Reveal Novel Biochemical Mechanisms and Predictive Biomarkers

Fibroin Delays Chilling Injury of Postharvest Banana Fruit via Enhanced Antioxidant Capability during Cold Storage

Untargeted Metabolomics Approach Reveals Diverse Responses of Pastinaca Sativa to Ozone and Wounding Stresses

The Ruminal Microbiome and Metabolome Alterations Associated with Diet-Induced Milk Fat Depression in Dairy Cows

Pharmacometabolomic Pathway Response of Effective Anticancer Agents on Different Diets in Rats with Induced Mammary Tumors

Intracellular Staphylococcus aureus Elicits the Production of Host Very Long-Chain Saturated Fatty Acids with Antimicrobial Activity

1H HR-MAS NMR-Based Metabolomics of Cancer Cells in Response to Treatment with the Diruthenium Trithiolato Complex [(p-MeC6H4iPr)2Ru2(SC6H4-p-But)3]+ (DiRu-1)

Anion Inhibition Profile of the β-Carbonic Anhydrase from the Opportunist Pathogenic Fungus Malassezia restricta Involved in Dandruff and Seborrheic Dermatitis

Metabolomics Analytics Workflow for Epidemiological Research: Perspectives from the Consortium of Metabolomics Studies (COMETS)

¹H HR-MAS NMR-Based Metabolomics of Cancer Cells in Response to Treatment with the Diruthenium Trithiolato Complex [(p-MeC₆H₄ⁱPr)₂Ru₂(SC₆H₄-p-Bu^t)₃]⁺ (DiRu-1)