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Metabolites, Volume 5, Issue 4

December 2015 - 11 articles

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Article

33 Citations

10,074 Views

35 Pages

Using Gene Essentiality and Synthetic Lethality Information to Correct Yeast and CHO Cell Genome-Scale Models

Ratul Chowdhury,
Anupam Chowdhury and
Costas D. Maranas

Metabolites2015, 5(4), 536-570;https://doi.org/10.3390/metabo5040536

29 September 2015

Essentiality (ES) and Synthetic Lethality (SL) information identify combination of genes whose deletion inhibits cell growth. This information is important for both identifying drug targets for tumor and pathogenic bacteria suppression and for flaggi...

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Metabolites - ISSN 2218-1989

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