- Letter
10 Citations
6,318 Views
2 Pages
Letter to the Editor of Metabolites
- Maureen R. Hanson and
- Arnaud Germain
Dear Editor, [...]
- 3.7Impact Factor
- 6.9CiteScore
- 17 daysTime to First Decision
Metabolites, Volume 10, Issue 5
May 2020 - 45 articles
Cover Story: Bidens pilosa has many bioactivities, owing to its diverse phytochemicals. These include chlorogenic acids, which occur as either regio- or geometrical isomers. To profile the CGA composition, extracts from tissues, callus, and cell suspensions were analyzed by UHPLC-qTOF-MS/MS. An ISCID method based on MS fragmentation capable of discriminating between closely related HCA derivatives of quinic acid was able to discriminate between positional isomers containing two different cinnamoyl moieties, such as a mixed di-ester of feruloyl-caffeoylquinic acid and coumaroyl-caffeoylquinic acid. Tissues and cell cultures of B. pilosa contained a combined total of 30 mono-, di-, and tri-substituted CGAs. In addition, tartaric acid esters as well as caftaric and chicoric acids were identified. Profiling revealed a differential distribution of these molecules across tissues types. View this paper<
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Articles (45)
- Article
8 Citations
3,982 Views
14 Pages
Insights into the Metabolome of the Cyanobacterium Leibleinia gracilis from the Lagoon of Tahiti and First Inspection of Its Variability
- Hiren Solanki,
- Manon Pierdet,
- Olivier P. Thomas and
- Mayalen Zubia
Cyanobacteria are known to produce a large diversity of specialized metabolites that can cause severe (eco)toxicological effects. In the lagoon of Tahiti, the benthic cyanobacterium Leibleinia gracilis is commonly found overgrowing the proliferative...
- Article
13 Citations
4,384 Views
15 Pages
Metabolomic Profiling of Nicotiana Spp. Nectars Indicate That Pollinator Feeding Preference Is a Stronger Determinant Than Plant Phylogenetics in Shaping Nectar Diversity
- Fredy A. Silva,
- Elizabeth C. Chatt,
- Siti-Nabilla Mahalim,
- Adel Guirgis,
- Xingche Guo,
- Daniel S. Nettleton,
- Basil J. Nikolau and
- Robert W. Thornburg
Floral nectar is a rich secretion produced by the nectary gland and is offered as reward to attract pollinators leading to improved seed set. Nectars are composed of a complex mixture of sugars, amino acids, proteins, vitamins, lipids, organic and in...
- Article
26 Citations
3,926 Views
14 Pages
Alterations in Tissue Metabolite Profiles with Amifostine-Prophylaxed Mice Exposed to Gamma Radiation
- Amrita K. Cheema,
- Yaoxiang Li,
- Michael Girgis,
- Meth Jayatilake,
- Oluseyi O. Fatanmi,
- Stephen Y. Wise,
- Thomas M. Seed and
- Vijay K. Singh
Acute exposure to high-dose ionizing irradiation has the potential to severely injure the hematopoietic system and its capacity to produce vital blood cells that innately serve to ward off infections and excessive bleeding. Developing a medical radia...
- Article
18 Citations
4,552 Views
26 Pages
An NMR-Based Approach to Identify Urinary Metabolites Associated with Acute Physical Exercise and Cardiorespiratory Fitness in Healthy Humans—Results of the KarMeN Study
- Sina Kistner,
- Manuela J. Rist,
- Maik Döring,
- Claudia Dörr,
- Rainer Neumann,
- Sascha Härtel and
- Achim Bub
Knowledge on metabolites distinguishing the metabolic response to acute physical exercise between fit and less fit individuals could clarify mechanisms and metabolic pathways contributing to the beneficial adaptations to exercise. By analyzing data f...
- Article
9 Citations
3,308 Views
14 Pages
Impact of Pre-Blood Collection Factors on Plasma Metabolomic Profiles
- Sheetal Hardikar,
- Richard D. Albrechtsen,
- David Achaintre,
- Tengda Lin,
- Svenja Pauleck,
- Mary Playdon,
- Andreana N. Holowatyj,
- Biljana Gigic,
- Petra Schrotz-King and
- Juergen Boehm
- + 9 authors
Demographic, lifestyle and biospecimen-related factors at the time of blood collection can influence metabolite levels in epidemiological studies. Identifying the major influences on metabolite concentrations is critical to designing appropriate samp...
- Article
67 Citations
7,288 Views
24 Pages
Metabolic Profiling of PGPR-Treated Tomato Plants Reveal Priming-Related Adaptations of Secondary Metabolites and Aromatic Amino Acids
- Msizi I. Mhlongo,
- Lizelle A. Piater,
- Paul A. Steenkamp,
- Nico Labuschagne and
- Ian A. Dubery
Plant growth–promoting rhizobacteria (PGPR) are beneficial microbes in the rhizosphere that can directly or indirectly stimulate plant growth. In addition, some can prime plants for enhanced defense against a broad range of pathogens and insect...
- Review
20 Citations
6,074 Views
13 Pages
Systems Biology ARDS Research with a Focus on Metabolomics
- Sayed M. Metwaly and
- Brent W. Winston
Acute respiratory distress syndrome (ARDS) is a clinical syndrome that inflicts a considerably heavy toll in terms of morbidity and mortality. While there are multitudes of conditions that can lead to ARDS, the vast majority of ARDS cases are caused...
- Article
69 Citations
7,079 Views
19 Pages
Tryptophan Metabolism, Inflammation, and Oxidative Stress in Patients with Neurovascular Disease
- Martin Hajsl,
- Alzbeta Hlavackova,
- Karolina Broulikova,
- Martin Sramek,
- Martin Maly,
- Jan E. Dyr and
- Jiri Suttnar
Atherosclerosis is a leading cause of major vascular events, myocardial infarction, and ischemic stroke. Tryptophan (TRP) catabolism was recognized as an important player in inflammation and immune response having together with oxidative stress (OS)...
- Article
26 Citations
5,511 Views
18 Pages
Cross-Species Comparison of Fruit-Metabolomics to Elucidate Metabolic Regulation of Fruit Polyphenolics Among Solanaceous Crops
- Carla Lenore F. Calumpang,
- Tomoki Saigo,
- Mutsumi Watanabe and
- Takayuki Tohge
Many solanaceous crops are an important part of the human daily diet. Fruit polyphenolics are plant specialized metabolites that are recognized for their human health benefits and their defensive role against plant abiotic and biotic stressors. Flavo...
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Metabolites - ISSN 2218-1989