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Diseases, Volume 2, Issue 1

March 2014 - 4 articles

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Articles (4)

  • Review
  • Open Access
38 Citations
9,248 Views
26 Pages

MeCP2-Related Diseases and Animal Models

  • Chinelo D. Ezeonwuka and
  • Mojgan Rastegar

27 January 2014

The role of epigenetics in human disease has become an area of increased research interest. Collaborative efforts from scientists and clinicians have led to a better understanding of the molecular mechanisms by which epigenetic regulation is involved...

  • Review
  • Open Access
6,614 Views
21 Pages

22 January 2014

Mitochondrial diseases, which altogether represent not so rare diseases, can be due to mutations either in the nuclear or mitochondrial genomes. Several model organisms or cell lines are usually employed to understand the mechanisms underlying diseas...

  • Review
  • Open Access
7 Citations
8,934 Views
21 Pages

Trypanosomatid Aquaporins: Roles in Physiology and Drug Response

  • Goutam Mandal,
  • Jose F. Orta,
  • Mansi Sharma and
  • Rita Mukhopadhyay

27 December 2013

In the class Kinetoplastida, we find an order of parasitic protozoans classified as Trypanosomatids. Three major pathogens form part of this order, Trypanosoma cruzi, Trypanosoma brucei, and Leishmania, which are responsible for disease and fatalitie...

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Diseases - ISSN 2079-9721