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Diseases, Volume 12, Issue 9

September 2024 - 32 articles

Cover Story: Obesity is a chronic disease known to be associated with several medical and psychosocial comorbidities, as well as adverse alterations in terms of body composition. Currently, different strategies are available and used for the management of obesity; one of these is the anti-obesity drugs strategy. This strategy is in continuous evolvement and advancement, determining a new era of obesity treatment. In particular, Tirzepatide a new drug that has been recently developed, showed a high effectiveness in terms of weight loss and was also shown to have beneficial effects in terms of obesity comorbidities that go beyond weight loss, such as improvements in type 2 diabetes and cardiovascular diseases. However, despite this fact, little is known about the effect of this drug on body composition compartments during weight loss in people with obesity. View this paper
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Articles (32)

  • Review
  • Open Access
6 Citations
16,696 Views
44 Pages

Beyond Pharmacology: A Narrative Review of Alternative Therapies for Anxiety Disorders

  • Zuzanna Antos,
  • Klaudia Zackiewicz,
  • Natalia Tomaszek,
  • Stefan Modzelewski and
  • Napoleon Waszkiewicz

16 September 2024

Background: Anxiety disorders significantly reduce patients’ quality of life. Current pharmacological treatments, primarily benzodiazepines and antidepressants, are associated with numerous side effects. Consequently, there is a continual searc...

  • Article
  • Open Access
1 Citations
2,809 Views
12 Pages

Identifying Childhood Risk Factors for Hepatitis B with a Focus on Vertical Transmission

  • Lorenza Forna,
  • Ancuta Lupu,
  • Laura Bozomitu,
  • Gabriela Paduraru,
  • Camelia Cojocariu,
  • Carmen Anton,
  • Irina Girleanu,
  • Cristina Maria Muzica and
  • Anca Trifan

16 September 2024

Background: Despite worldwide vaccination efforts, Hepatitis B virus (HBV) infection remains a significant global health burden, particularly in regions where vertical transmission is prevalent. Given Romania’s history as an endemic area for he...

  • Communication
  • Open Access
2,501 Views
9 Pages

The Impact of Human Papillomavirus Infections on Recurrent Pregnancy Loss: A Review of the Literature

  • Dimitra Dedousi,
  • Anastasios Potiris,
  • Athanasios Zikopoulos,
  • Theodoros Karampitsakos,
  • Spyridon Topis,
  • Charikleia Skentou,
  • Angeliki Gerede,
  • Panagiotis Christopoulos,
  • Athanasios Zachariou and
  • Ekaterini Domali
  • + 2 authors

13 September 2024

Human papillomavirus (HPV) infections are significantly associated with multiple adverse reproductive outcomes such as miscarriages. Pregnant women are more susceptible to an HPV infection and its prevalence increases as pregnancy progresses. In this...

  • Article
  • Open Access
1 Citations
6,525 Views
13 Pages

A Multi-Pathogen Retrospective Study in Patients Hospitalized for Acute Gastroenteritis

  • Antonella Zizza,
  • Marcello Guido,
  • Raffaella Sedile,
  • Marzia Benelli,
  • Milva Nuzzo,
  • Pasquale Paladini,
  • Anacleto Romano and
  • Pierfrancesco Grima

12 September 2024

Acute gastroenteritis (AGE) is a gastrointestinal tract disease often caused by consuming food or water contaminated by bacteria, viruses, or parasites, that can lead to severe symptoms requiring hospitalization. A retrospective study on patients adm...

  • Article
  • Open Access
2,151 Views
12 Pages

Health-Related Quality of Life among Elderly Patients in Urban Bangladesh: A Cross-Sectional Study

  • Joynal Abedin Imran,
  • Amal K. Mitra,
  • Marzana Afrooj Ria,
  • Tumpa Mitra,
  • Jannatul Ferdous Konok,
  • Sadia Akter Shuchi and
  • Pradip Kumar Saha

11 September 2024

Quality of life (QoL) focuses on a person’s ability to live a fulfilling life. It helps in determining successful aging in the elderly population. Because of a scarcity of information regarding predictors of QoL in the elderly population in dev...

  • Article
  • Open Access
2 Citations
2,170 Views
12 Pages

The Use of Kidney Biomarkers, Nephrin and KIM-1, for the Detection of Early Glomerular and Tubular Damage in Patients with Acromegaly: A Case–Control Pilot Study

  • Iulia Stefania Plotuna,
  • Melania Balas,
  • Ioana Golu,
  • Daniela Amzar,
  • Roxana Popescu,
  • Ligia Petrica,
  • Adrian Vlad,
  • Daniel Luches,
  • Daliborca Cristina Vlad and
  • Mihaela Vlad

11 September 2024

Background: Acromegaly is a rare disorder caused by excessive growth hormone (GH) secreted from a pituitary tumor. High levels of GH and insulin growth factor-1 can lead to renal hypertrophy, as well as to diabetes mellitus and hypertension, which ne...

  • Case Report
  • Open Access
1,617 Views
10 Pages

Modified Prophylactic Donor Lymphocyte Infusion (DLI) in an Adult T Cell Lymphoma/Leukemia (ATLL) Patient—Modality of Relapse Prevention

  • Alexandra Ionete,
  • Alexandru Bardas,
  • Zsofia Varady,
  • Madalina Vasilica,
  • Orsolya Szegedi and
  • Daniel Coriu

11 September 2024

Adult T-cell Leukemia/Lymphoma (ATLL) is a rare but aggressive malignancy associated with the human T-cell lymphotropic virus type 1 (HTLV-1). ATLL is a challenging malignancy characterized by its aggressive nature and poor prognosis. Despite advance...

  • Review
  • Open Access
17 Citations
14,254 Views
21 Pages

Empirical Treatments for Male Infertility: A Focus on Lifestyle Modifications and Medicines

  • Aris Kaltsas,
  • Athanasios Zachariou,
  • Fotios Dimitriadis,
  • Michael Chrisofos and
  • Nikolaos Sofikitis

11 September 2024

Background/Objectives: Male infertility is a prevalent issue impacting numerous couples worldwide. This review aims to evaluate the effectiveness of empirical therapies for male infertility, focusing on both lifestyle modifications and medical treatm...

  • Systematic Review
  • Open Access
4 Citations
2,715 Views
13 Pages

Prevalence and Risk Factors of Renal Artery Stenosis in Patients Undergoing Simultaneous Coronary and Renal Artery Angiography: A Systematic Review and Meta-Analysis of 31,689 Patients from 31 Studies

  • Konstantin Schwarz,
  • Ida Straume Bah,
  • Maximilian Will,
  • Chun Shing Kwok,
  • Julia Mascherbauer,
  • Marko Kumric,
  • Josko Bozic and
  • Josip A. Borovac

11 September 2024

Background/Objectives: Renal artery stenosis (RAS) is associated with coronary artery disease (CAD), exacerbation of arterial hypertension, and progression to heart failure, but remains frequently unrecognized in clinical practice. Methods: We conduc...

  • Article
  • Open Access
3 Citations
2,663 Views
28 Pages

10 September 2024

Hydroperoxides (ROOHs) are known as damaging agents capable of mediating mutation, while a role as signaling agents through oxidation of protein sulfhydryls that can alter cancer-related pathways has gained traction. Glutathione peroxidase 2 (GPX2) i...

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Diseases - ISSN 2079-9721