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Diseases, Volume 11, Issue 4

December 2023 - 61 articles

Cover Story: A meta-analysis was conducted to find out if probiotics are effective in adults with gastroenteritis. In the systematic review, the probiotics were effective in the treatment and/or prevention of chronic inflammatory bowel disease, including ulcerative colitis and Crohn’s disease. However, the meta-analysis did not demonstrate any significant protective effects of the probiotics. The studies found that either the short-term or long-term administration of probiotics is safe. View this paper
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Articles (61)

  • Article
  • Open Access
14 Citations
7,963 Views
14 Pages

Correlation of HbA1c Level with Lipid Profile in Type 2 Diabetes Mellitus Patients Visiting a Primary Healthcare Center in Jeddah City, Saudi Arabia: A Retrospective Cross-Sectional Study

  • Abdulaziz Yahya Sharahili,
  • Shabir Ahmad Mir,
  • Sahar ALDosari,
  • Md Dilshad Manzar,
  • Bader Alshehri,
  • Ayoub Al Othaim,
  • Fayez Alghofaili,
  • Yahya Madkhali,
  • Kamal Shaker Albenasy and
  • Jazi S. Alotaibi

31 October 2023

Introduction: Type 2 diabetes mellitus (T2DM) patients are at high risk of dyslipidemia, which in turn is associated with macrovascular diseases, such as heart diseases and stroke, and microvascular diseases, such as neuropathy and nephropathy. There...

  • Review
  • Open Access
4 Citations
4,178 Views
21 Pages

Trends in Nanoparticles for Leishmania Treatment: A Bibliometric and Network Analysis

  • Gabriel Mazón-Ortiz,
  • Galo Cerda-Mejía,
  • Eberto Gutiérrez Morales,
  • Karel Diéguez-Santana,
  • Juan M. Ruso and
  • Humberto González-Díaz

28 October 2023

Leishmaniasis is a neglected tropical illness with a wide variety of clinical signs ranging from visceral to cutaneous symptoms, resulting in millions of new cases and thousands of fatalities reported annually. This article provides a bibliometric an...

  • Systematic Review
  • Open Access
7 Citations
6,792 Views
13 Pages

The Effectiveness and Safety of Long-Term Macrolide Therapy for COPD in Stable Status: A Systematic Review and Meta-Analysis

  • Kazunori Nakamura,
  • Yukio Fujita,
  • Hao Chen,
  • Kohei Somekawa,
  • Fumihiro Kashizaki,
  • Harumi Koizumi,
  • Kenichi Takahashi,
  • Nobuyuki Horita,
  • Yu Hara and
  • Shigeo Muro
  • + 1 author

27 October 2023

Background: Chronic obstructive pulmonary disease (COPD) is a prevalent condition with fewer treatments available as the severity increases. Previous systematic reviews have demonstrated the benefits of long-term macrolide use. However, the therapeut...

  • Article
  • Open Access
3,153 Views
10 Pages

The Association between Non-Invasive Ventilation and the Rate of Ventilator-Associated Pneumonia

  • Hollie Saunders,
  • Subekshya Khadka,
  • Rabi Shrestha,
  • Arvind Balavenkataraman,
  • Alexander Hochwald,
  • Colleen Ball and
  • Scott A. Helgeson

27 October 2023

Ventilator-associated pneumonia (VAP) has significant effects on patient outcomes, including prolonging the duration of both mechanical ventilation and stay in the intensive care unit (ICU). The aim of this study was to assess the association between...

  • Article
  • Open Access
14 Citations
4,056 Views
14 Pages

Activity of Bacteriophage D29 Loaded on Nanoliposomes against Macrophages Infected with Mycobacterium tuberculosis

  • Ana P. B. Silva,
  • Cesar Augusto Roque-Borda,
  • Christian S. Carnero Canales,
  • Laura Maria Duran Gleriani Primo,
  • Isabel C. Silva,
  • Camila M. Ribeiro,
  • Marlus Chorilli,
  • Patrícia Bento da Silva,
  • Joás L. Silva and
  • Fernando Rogério Pavan

26 October 2023

The search for new antimicrobial agents is a continuous struggle, mainly because more and more cases of resistant strains are being reported. Mycobacterium tuberculosis (MTB) is the main microorganism responsible for millions of deaths worldwide. The...

  • Article
  • Open Access
2 Citations
2,404 Views
14 Pages

Preoperative Balloon-Occluded Transcatheter Arterial Chemoembolization Followed by Surgical Resection: Pathological Evaluation of Necrosis

  • Jihoon Kim,
  • Dong Il Gwon,
  • Yonghun Kim,
  • Gun Ha Kim,
  • Seong Ho Kim,
  • Hee Ho Chu,
  • Jin Hyoung Kim,
  • Ji Hoon Shin,
  • Gi-Young Ko and
  • Hyun-Ki Yoon

24 October 2023

This study investigates the clinical and pathological outcomes of preoperative balloon-occluded transcatheter arterial chemoembolization (B-TACE) in patients with single hepatocellular carcinoma (HCC). The data are from 25 consecutive patients who un...

  • Review
  • Open Access
23 Citations
10,858 Views
22 Pages

Progress and Perspectives in Colon Cancer Pathology, Diagnosis, and Treatments

  • Noor Alrushaid,
  • Firdos Alam Khan,
  • Ebtesam Al-Suhaimi and
  • Abdelhamid Elaissari

24 October 2023

Worldwide, colon cancer is the third most frequent malignancy and the second most common cause of death. Although it can strike anybody at any age, colon cancer mostly affects the elderly. Small, non-cancerous cell clusters inside the colon, commonly...

  • Article
  • Open Access
2 Citations
2,298 Views
11 Pages

Examining the Effects of Dasatinib, Sorafenib, and Nilotinib on Vascular Smooth Muscle Cells: Insights into Proliferation, Migration, and Gene Expression Dynamics

  • Khalid Alhazzani,
  • Abdullah Almangour,
  • Abdulaziz Alsalem,
  • Mohammed Alqinyah,
  • Abdullah S. Alhamed,
  • Hussain N. Alhamami and
  • Ahmed Z. Alanazi

23 October 2023

Background: Dasatinib, nilotinib, and sorafenib are clinically proven tyrosine kinase inhibitors (TKIs) used for the treatment of leukemia and hepatocellular carcinoma. However, there is a growing concern regarding cardiotoxicity associated with thei...

  • Systematic Review
  • Open Access
6 Citations
3,137 Views
16 Pages

23 October 2023

The objective of this systematic review and meta-analysis was to assess and contrast the efficacy and safety of combining erlotinib and bevacizumab with erlotinib alone in the treatment of patients with advanced non-small cell lung cancer (NSCLC). Th...

  • Article
  • Open Access
1 Citations
2,960 Views
14 Pages

Lipoprotein(a) and Low-Molecular-Weight Apo(a) Phenotype as Determinants of New Cardiovascular Events in Patients with Premature Coronary Heart Disease

  • Olga I. Afanasieva,
  • Alexandra V. Tyurina,
  • Marat V. Ezhov,
  • Oxana A. Razova,
  • Elena A. Klesareva and
  • Sergei N. Pokrovsky

18 October 2023

Background. Lipoprotein(a) (Lp(a)) is a genetic risk factor of atherosclerotic cardiovascular diseases (ASCVDs). Proprotein convertase subtilisin/kexin type 9 (PCSK9) is related to vascular inflammation and detected in atherosclerotic plaques. A temp...

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Diseases - ISSN 2079-9721