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Biology, Volume 7, Issue 1

2018 March - 21 articles

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Articles (21)

  • Review
  • Open Access
63 Citations
10,560 Views
13 Pages

6 March 2018

It is abundantly clear that the development of gene editing technologies, represents a potentially powerful force for good with regard to human and animal health and addressing the challenges we continue to face in a growing global population. This n...

  • Review
  • Open Access
7,286 Views
19 Pages

26 February 2018

Evolutionary change comes from natural and other forms of selection acting on existing anatomical and physiological variants. While much is known about selection, little is known about the details of how genetic mutation leads to the range of heritab...

  • Article
  • Open Access
16 Citations
8,595 Views
13 Pages

Human Intrinsic Factor Expression for Bioavailable Vitamin B12 Enrichment in Microalgae

  • Serena Lima,
  • Conner L. Webb,
  • Evelyne Deery,
  • Colin Robinson and
  • Julie A. Z. Zedler

19 February 2018

Dietary supplements and functional foods are becoming increasingly popular complements to regular diets. A recurring ingredient is the essential cofactor vitamin B12 (B12). Microalgae are making their way into the dietary supplement and functional fo...

  • Review
  • Open Access
238 Citations
19,366 Views
25 Pages

Microwave-Assisted Extraction for Microalgae: From Biofuels to Biorefinery

  • Rahul Vijay Kapoore,
  • Thomas O. Butler,
  • Jagroop Pandhal and
  • Seetharaman Vaidyanathan

15 February 2018

The commercial reality of bioactive compounds and oil production from microalgal species is constrained by the high cost of production. Downstream processing, which includes harvesting and extraction, can account for 70–80% of the total cost of produ...

  • Article
  • Open Access
12 Citations
7,594 Views
14 Pages

Detection and Enhancement of Ketocarotenoid Accumulation in the Newly Isolated Sarcinoid Green Microalga Chlorosarcinopsis PY02

  • Peelada Cherdchukeattisak,
  • Paul D. Fraser,
  • Saul Purton and
  • Thanyanan Wannathong Brocklehurst

12 February 2018

The sarcinoid alga PY02 is a newly isolated soil alga native to western Thailand. In this study PY02 is described, the carotenoid profile of the green and red forms of the algal cells are compared, and the effect of nitrogen reduction and media volum...

  • Article
  • Open Access
2 Citations
6,501 Views
13 Pages

9 February 2018

Late-onset Alzheimer’s disease (LOAD) and age are significantly correlated such that one-third of Americans beyond 85 years of age are afflicted. We have designed and implemented a pilot study that combines systems biology approaches with traditional...

  • Review
  • Open Access
45 Citations
8,612 Views
24 Pages

Sex Steroid-Mediated Control of Oviductal Function in Cattle

  • Mario Binelli,
  • Angela Maria Gonella-Diaza,
  • Fernando Silveira Mesquita and
  • Claudia Maria Bertan Membrive

2 February 2018

In cattle, the oviduct is a tubular organ that connects the ovary and the uterus. The oviduct lumen stages a dynamic set of cellular and molecular interactions to fulfill the noble role of generating a new individual. Specific anatomical niches along...

  • Article
  • Open Access
122 Citations
15,067 Views
18 Pages

Potential of New Isolates of Dunaliella Salina for Natural β-Carotene Production

  • Yanan Xu,
  • Iskander M. Ibrahim,
  • Chiziezi I. Wosu,
  • Ami Ben-Amotz and
  • Patricia J. Harvey

1 February 2018

The halotolerant microalga Dunaliella salina has been widely studied for natural β-carotene production. This work shows biochemical characterization of three newly isolated Dunaliella salina strains, DF15, DF17, and DF40, compared with D. salina CCAP...

  • Article
  • Open Access
40 Citations
10,130 Views
21 Pages

Comparing Nutrient Removal from Membrane Filtered and Unfiltered Domestic Wastewater Using Chlorella vulgaris

  • Elyssia Mayhead,
  • Alla Silkina,
  • Carole A. Llewellyn and
  • Claudio Fuentes-Grünewald

19 January 2018

The nutrient removal efficiency of Chlorella vulgaris cultivated in domestic wastewater was investigated, along with the potential to use membrane filtration as a pre-treatment tool during the wastewater treatment process. Chlorella vulgaris was batc...

  • Article
  • Open Access
24 Citations
7,817 Views
13 Pages

Intraperitoneal Administration of Oxygen/Ozone to Rats Reduces the Pancreatic Damage Induced by Streptozotocin

  • Dario Siniscalco,
  • Maria Consiglia Trotta,
  • Anna Lisa Brigida,
  • Rosa Maisto,
  • Margherita Luongo,
  • Franca Ferraraccio,
  • Michele D’Amico and
  • Clara Di Filippo

11 January 2018

Background: The rat model of streptozotocin (STZ)-induced pancreatic damage was used to examine whether a systemic oxygen/ozone mixture could be beneficial for the pancreas by reducing the machinery of the local detrimental mediators released by STZ....

  • Article
  • Open Access
5 Citations
5,842 Views
9 Pages

The Kiss Switch Brings Inactive R3C Ligase Ribozyme Back to Life

  • Kana Tanizawa,
  • Sayuri Uchida,
  • Eri Kurihara,
  • Takuya Umehara and
  • Koji Tamura

9 January 2018

R3C ligase ribozyme catalyzes the nucleophilic attack by a 3′-hydroxyl on a 5′-α-phosphorus of triphosphates to form a 3′-5′-phosphodiester bond. In the present study, although the truncation of R3C ribozyme was accompanied by a large reduction in li...

  • Review
  • Open Access
48 Citations
8,288 Views
21 Pages

Effects of Sex Steroids on Fish Leukocytes

  • Elena Chaves-Pozo,
  • Alfonsa García-Ayala and
  • Isabel Cabas

9 January 2018

In vertebrates, in addition to their classically reproductive functions, steroids regulate the immune system. This action is possible mainly due to the presence of steroid receptors in the different immune cell types. Much evidence suggests that the...

  • Article
  • Open Access
53 Citations
10,518 Views
13 Pages

Bacteriophage ΦSA012 Has a Broad Host Range against Staphylococcus aureus and Effective Lytic Capacity in a Mouse Mastitis Model

  • Hidetomo Iwano,
  • Yusuke Inoue,
  • Takuji Takasago,
  • Hironori Kobayashi,
  • Takaaki Furusawa,
  • Kotomi Taniguchi,
  • Jumpei Fujiki,
  • Hiroshi Yokota,
  • Masaru Usui and
  • Yutaka Tamura
  • + 3 authors

9 January 2018

Bovine mastitis is an inflammation of the mammary gland caused by bacterial infection in dairy cattle. It is the most costly disease in the dairy industry because of the high use of antibiotics. Staphylococcus aureus is one of the major causative age...

  • Article
  • Open Access
1 Citations
6,779 Views
16 Pages

Interaction Analysis of Longevity Interventions Using Survival Curves

  • Stefan Nowak,
  • Johannes Neidhart,
  • Ivan G. Szendro,
  • Jonas Rzezonka,
  • Rahul Marathe and
  • Joachim Krug

6 January 2018

A long-standing problem in ageing research is to understand how different factors contributing to longevity should be expected to act in combination under the assumption that they are independent. Standard interaction analysis compares the extension...

  • Review
  • Open Access
7 Citations
7,237 Views
16 Pages

Family A and B DNA Polymerases in Cancer: Opportunities for Therapeutic Interventions

  • Vinit Shanbhag,
  • Shrikesh Sachdev,
  • Jacqueline A. Flores,
  • Mukund J. Modak and
  • Kamalendra Singh

2 January 2018

DNA polymerases are essential for genome replication, DNA repair and translesion DNA synthesis (TLS). Broadly, these enzymes belong to two groups: replicative and non-replicative DNA polymerases. A considerable body of data suggests that both groups...

  • Article
  • Open Access
15 Citations
7,615 Views
16 Pages

Harvesting Environmental Microalgal Blooms for Remediation and Resource Recovery: A Laboratory Scale Investigation with Economic and Microbial Community Impact Assessment

  • Jagroop Pandhal,
  • Wai L. Choon,
  • Rahul V. Kapoore,
  • David A. Russo,
  • James Hanotu,
  • I. A. Grant Wilson,
  • Pratik Desai,
  • Malcolm Bailey,
  • William J. Zimmerman and
  • Andrew S. Ferguson

29 December 2017

A laboratory based microflotation rig termed efficient FLOtation of Algae Technology (eFLOAT) was used to optimise parameters for harvesting microalgal biomass from eutrophic water systems. This was performed for the dual objectives of remediation (n...

  • Review
  • Open Access
41 Citations
11,291 Views
10 Pages

Incomplete Penetrance and Variable Expressivity: Hallmarks in Channelopathies Associated with Sudden Cardiac Death

  • Monica Coll,
  • Alexandra Pérez-Serra,
  • Jesus Mates,
  • Bernat Del Olmo,
  • Marta Puigmulé,
  • Anna Fernandez-Falgueras,
  • Anna Iglesias,
  • Ferran Picó,
  • Laura Lopez and
  • Oscar Campuzano
  • + 1 author

26 December 2017

Sudden cardiac death is defined as an unexpected decease of cardiac origin. In individuals under 35 years old, most of these deaths are due to familial arrhythmogenic syndromes of genetic origin, also known as channelopathies. These familial cardiac...

  • Article
  • Open Access
74 Citations
12,034 Views
15 Pages

Media Screening for Obtaining Haematococcus pluvialis Red Motile Macrozooids Rich in Astaxanthin and Fatty Acids

  • Thomas O. Butler,
  • Gordon J. McDougall,
  • Raymond Campbell,
  • Michele S. Stanley and
  • John G. Day

26 December 2017

Astaxanthin from Haematococcus pluvialis is commercially produced in a two-stage process, involving green vegetative (macrozooid) and red aplanospore stages. This approach has been scaled up to an industrial process but constraints limit its commerci...

  • Feature Paper
  • Article
  • Open Access
11 Citations
7,679 Views
15 Pages

23 December 2017

It is often assumed, but not established, that the major neurodegenerative diseases, such as Parkinson’s disease, are not just age-dependent (their incidence changes with time) but actually aging-dependent (their incidence is coupled to the process t...

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Biology - ISSN 2079-7737