Journal of Functional Biomaterials, Volume 14, Issue 10
October 2023 - 48 articles
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Cover Story: A site-specific, controlled-release system is necessary to address the challenge of hearing loss by facilitating drug delivery to the cochlea. The design should be tailored to the anatomical dimensions of the human, possess geometrical features for drug encapsulation and release, and be safe. With the use of the high-precision two-photon polymerization 3D printing technique, shape and size fidelity as well as reproducibility can be achieved. Cochlear implants of 2.4 mm with internal pores of 20 μm and 60 μm are reliably fabricated in this study. Moreover, an analysis of their constituting material post-fabrication shows a robust degree of polymerization and cytocompatibility with murine macrophages, underscoring the safety of the implants. (Cover illustration created with the use of BioRender.com). View this paper 
