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Journal of Clinical Medicine, Volume 12, Issue 9

May-1 2023 - 303 articles

Cover Story: Head and neck (HN) squamous cell carcinomas (SCCs) originate from the epithelial cells of the mucosal linings of the upper aerodigestive tract, which includes the oral cavity, the pharynx, the larynx, and the sinonasal cavities. Human papilloma virus (HPV) is another independent risk factor for oropharyngeal SCC, but it is only a minor contributor to oral cavity SCC (OSCC). Betel quid chewing is also an established risk factor in southeast Asian countries. However, OSCC, and especially oral tongue cancer, incidence has been reported to be increasing in several countries, suggesting risk factors that have not been identified yet. This review summarizes the established risk factors for oral cavity squamous cell carcinomas and examines other undemonstrated risk factors for HNSCC. View this paper
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Articles (303)

  • Case Report
  • Open Access
6 Citations
2,646 Views
9 Pages

Zygomatic Implant Insertion in MRONJ: A Case Report with a Follow-Up of 3 Years

  • Funda Goker,
  • Emma Grecchi,
  • Massimo Del Fabbro,
  • Salvatore Longoni,
  • Luigi Vito Stefanelli and
  • Francesco Grecchi

The oral rehabilitation of MRONJ patients represents a challenging situation. Conventional dental implant insertion is not indicated because of the risk of creating a new necrotic area. This case study describes the oral rehabilitation of a 78-year-o...

  • Review
  • Open Access
41 Citations
11,905 Views
16 Pages

Application and Progress of Artificial Intelligence in Fetal Ultrasound

  • Sushan Xiao,
  • Junmin Zhang,
  • Ye Zhu,
  • Zisang Zhang,
  • Haiyan Cao,
  • Mingxing Xie and
  • Li Zhang

Prenatal ultrasonography is the most crucial imaging modality during pregnancy. However, problems such as high fetal mobility, excessive maternal abdominal wall thickness, and inter-observer variability limit the development of traditional ultrasound...

  • Article
  • Open Access
9 Citations
3,364 Views
16 Pages

Assessment and Monitoring of the Quality of Clinical Pathways in Patients with Depressive Disorders: Results from a Multiregional Italian Investigation on Mental Health Care Quality (the QUADIM Project)

  • Matteo Monzio Compagnoni,
  • Giulia Caggiu,
  • Liliana Allevi,
  • Angelo Barbato,
  • Flavia Carle,
  • Barbara D’Avanzo,
  • Teresa Di Fiandra,
  • Lucia Ferrara,
  • Andrea Gaddini and
  • Cristina Giordani
  • + 6 authors

Ensuring adequate quality of care to patients with severe mental disorders remains a challenge. The implementation of clinical indicators aimed at assessing the quality of health care pathways delivered is crucial for the improvement of mental health...

  • Article
  • Open Access
12 Citations
4,102 Views
13 Pages

Gender Differences in Neuromuscular Control during the Preparation Phase of Single-Leg Landing Task in Badminton

  • Zhe Hu,
  • Yanan Zhang,
  • Tengfei Dong,
  • Maolin Dong,
  • Sukwon Kim and
  • Youngsuk Kim

Background: Studies on the biomechanical mechanisms of an anterior cruciate ligament (ACL) injury have been extensively studied, but studies on the neuromuscular control-related risk factors for an ACL injury in specific maneuvers have not been repor...

  • Article
  • Open Access
5 Citations
4,701 Views
9 Pages

This study’s aim was to investigate the association between optic disc morphology and the occurrence of paracentral scotoma in eyes with open-angle glaucoma (OAG) and myopia. Two-hundred and eleven myopic eyes with OAG were classified into thre...

  • Article
  • Open Access
2,422 Views
10 Pages

The Clinical Significance of Serum Free Light Chains in Bladder Cancer

  • Monika Gudowska-Sawczuk,
  • Jacek Kudelski,
  • Michał Olkowicz,
  • Grzegorz Młynarczyk,
  • Piotr Chłosta and
  • Barbara Mroczko

This research aimed to assess the clinical usefulness of serum kappa (κ) and lambda (λ) free light chains (FLCs) in patients with bladder cancer (BC). One hundred samples were collected and analysed from healthy volunteers (C) and bladde...

  • Article
  • Open Access
1 Citations
2,482 Views
11 Pages

Does Tobacco Smoking Affect the Postoperative Outcome of MIS Lumbar Decompression Surgery?

  • Morsi Khashan,
  • Dror Ofir,
  • Uri Hochberg,
  • Haggai Schermann,
  • Gilad J. Regev,
  • Zvi Lidar and
  • Khalil Salame

Background: Tobacco smoking is a major cause of morbidity and mortality worldwide. Several authors reported a significant negative impact of smoking on the outcome of spinal surgeries. However, comparative studies on the effect of smoking on the outc...

  • Brief Report
  • Open Access
3 Citations
3,416 Views
7 Pages

Removal of Sub-Internal Limiting Membrane Hemorrhage Secondary to Retinal Arterial Macroaneurysm Rupture: Internal Limiting Membrane Non-Peeling Technique

  • Akari Kimura,
  • Hisanori Imai,
  • Yukako Iwane,
  • Maya Kishimoto,
  • Yasuyuki Sotani,
  • Hiroko Yamada,
  • Wataru Matsumiya,
  • Akiko Miki,
  • Sentaro Kusuhara and
  • Makoto Nakamura

The appropriate surgical technique to improve the closure rate of perioperative full-thickness macular hole (FTMH) secondary to submacular hemorrhage (SMH) with sub-internal limiting membrane (ILM) hemorrhage caused by retinal arterial macroaneurysm...

  • Article
  • Open Access
4 Citations
3,358 Views
12 Pages

Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) Is a Biomarker Associated with Left Ventricular Hypertrophy in the Elderly, Specifically in Women

  • Rafał Nikodem Wlazeł,
  • Agnieszka Guligowska,
  • Zuzanna Chrząstek,
  • Tomasz Kostka,
  • Anna Jegier and
  • Iwona Szadkowska

Left ventricular hypertrophy (LVH) may result in the development of heart failure, which is widespread among people of advanced age. The pathophysiology of LVH is complex and its biochemical pathways are not fully understood in this group. Elevated s...

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J. Clin. Med. - ISSN 2077-0383