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Membranes, Volume 16, Issue 10

2026 October - 44 articles

Cover Story: The isolation of extracellular vesicles (EVs) from complex biological fluids remains challenging. In this study, a magnetic solid phase was developed using silica-coated nanoparticles functionalized with a mixture of five VHH–eGFP constructs. The magnetic material was characterized to evaluate its structural and surface properties. The solid phase was used for the immunoaffinity isolation of EVs from human plasma. The EV-enriched preparations were characterized by several analytical techniques. Nanoparticle tracking analysis revealed a median particle diameter of 124 nm. Flow cytometry detected the EV-associated markers CD9, CD63, and CD81. These findings support the use of the developed magnetic solid phase for the immunoaffinity isolation of EVs. View this paper
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Articles (44)

  • Article
  • Open Access
182 Views
25 Pages

21 October 2026

Membrane fouling limits the sustainable application of polymeric membranes in wastewater treatment and water reuse. Strong adsorption of biomacromolecules and microorganisms can cause irreversible fouling, reducing membrane permeability and operation...

(This article belongs to the Section Membrane Applications for Water Treatment)
  • Article
  • Open Access
231 Views
35 Pages

21 October 2026

Water-in-oil (W/O) emulsion treatment is challenging because efficient membrane separation requires simultaneous control of oil transport, water rejection, interfacial interactions, and fouling resistance. However, the coupled effects of operating pr...

(This article belongs to the Special Issue Advanced Pressure-Driven Membranes for Real/Complex Water Matrices: From Materials Design to Process Optimization)
  • Review
  • Open Access
150 Views
26 Pages

Electromembrane Extraction for Metal and Metalloid Analysis: Species-Dependent Transport, Coordinated Method Design, and Evidence-Based Translation

  • Yi Zheng,
  • Yan Xing,
  • Fen Wang,
  • Hongliang Wang and ,
  • Fengqing Han,
  • Cong Li,
  • Ying Ren,
  • Guanglin Wang,
  • Bin Lin and
  • Shuang Zhou
  • + 5 authors+ 0 author

20 October 2026

Electromembrane extraction (EME) applies an electric field and a supported liquid membrane to transfer charged analytes into a small acceptor phase. For metal and metalloid analysis, the field contribution is coupled to aqueous speciation, interfacia...

(This article belongs to the Special Issue Functionalized Membranes: New Trends in Preparation and Advanced Applications)
  • Review
  • Open Access
454 Views
37 Pages

Towards Intelligent Membrane Systems: A Critical Analysis of Digital Twin–ML Integration for Real–Time Process Optimization, Fouling Management, and Autonomous Design

  • Olawumi O. Sadare,
  • Samuel P. Alonge,
  • Azeez G. Akinyemi,
  • Abass A. Adesina and ,
  • Shukrah Adesola-Olabiyi and
  • Lanrewaju I. Fajimi
  • + 1 author+ 0 author

20 October 2026

Membrane separation is central to potable water production, wastewater reclamation, desalination, gas separation, and decarbonization, yet its economics remain constrained by fouling and by a gap between process data and timely operating decisions. D...

(This article belongs to the Special Issue Machine Learning-Enabled Digital Twins for Membrane Process Optimisation)
  • Article
  • Open Access
298 Views
19 Pages

Molecularly Imprinted PDMS/MIL@MITpBD Mixed Matrix Membranes for β-Damascone Separation

  • Pei He,
  • Tao Zhang,
  • Xinru Zhang,
  • Shiyun Tang and ,
  • Jinghui Wang and
  • Yonghong Wang
  • + 1 author+ 0 author

19 October 2026

β-damascone (β-DC) has low content in nature and poor thermal stability, so conventional separation methods suffer from low separation efficiency. Pervaporation membrane separation has garnered significant interest owing to its green and en...

(This article belongs to the Special Issue Design and Functionalization of Separation Membranes for Advanced Applications)
  • Article
  • Open Access
248 Views
21 Pages

Low-Cost 3D-Printed Kaolin–Rice-Husk Microporous Membranes for Microplastic Removal: A Comparative Study with a Commercial Ceramic Membrane

  • Gulzat Demeuova,
  • Aliya Satayeva,
  • Zhanserik Shadiyar,
  • Alzhan Baimenov and ,
  • Elizabeth Arkhangelsky,
  • Zhuldyz Baimenova and
  • Arailym Kamal
  • + 2 authors+ 0 author

19 October 2026

Microplastics (MPs) are pervasive emerging contaminants in freshwater and drinking-water systems, and conventional treatment processes may achieve insufficient removal of smaller MP fractions. Membrane filtration provides an effective barrier to MPs;...

(This article belongs to the Special Issue Membrane Processes for Microplastic and Nanoplastic Removal)
  • Article
  • Open Access
117 Views
14 Pages

19 October 2026

This study evaluates the effect of the reduction degree of graphene oxide on the cyclization of polyacrylonitrile (PAN) in composite PAN/GO membranes prepared by phase inversion. All composite membranes contained the same amount of graphene-based add...

(This article belongs to the Section Membrane Applications for Other Areas)
  • Article
  • Open Access
258 Views
23 Pages

Bilayer Polycaprolactone (Mitomycin C)/Poly(L-Lactic Acid)/Gelatine (Dimethyloxalylglycine) Nanofibres for Diabetic Wound Repair

  • Renxi Zhu,
  • Qiang Wang,
  • Zhiwei Chen,
  • Feng Chen and ,
  • Congcong Yang,
  • Jianping Tao,
  • Lunjie Zhao,
  • Yukui Gao,
  • Jingwei Zhang and
  • Dan Li
  • + 7 authors+ 2 authors

16 October 2026

Background: Diabetic skin wounds arise from chronic hyperglycaemia, peripheral neuropathy, microvascular dysfunction, and compromised immunity. Chronic ulcers are further complicated by infection and local ischaemia–hypoxia, which collectively...

(This article belongs to the Special Issue Advances in Biomembrane Structure, Dynamics, and Function)
  • Review
  • Open Access
517 Views
24 Pages

16 October 2026

The blood–brain barrier (BBB) is a highly selective membrane that restricts the delivery of therapeutics into the brain. In this review, we consider a number of computational techniques that can be used to assess BBB transport and central nervo...

(This article belongs to the Special Issue Simulation and Artificial Intelligence Method Development for Complex Membrane Transport)
  • Article
  • Open Access
313 Views
13 Pages

14 October 2026

Patients with chronic kidney disease (CKD) face a substantial cardiovascular burden, with altered erythrocyte membrane fatty acids (FAs) representing potential markers of adverse outcomes. However, comprehensive evaluations according to varying level...

  • Article
  • Open Access
237 Views
15 Pages

14 October 2026

S-palmitoylation is a reversible lipid modification that can alter protein localization, stability, interactions and signaling, but detection of a modified cysteine does not establish its functional importance. Post-translational Modification-Palmoyl...

  • Review
  • Open Access
517 Views
33 Pages

Beyond Permeability Prediction: Machine Learning for Gas-Separation Membranes from Data Curation to Experimentally Validated Discovery

  • Zhengda Lin,
  • Bingjie Yan,
  • Xinhao Sun,
  • Zhe Fu and ,
  • Xingwei Du and
  • Jun Zhang
  • + 1 author+ 0 author

13 October 2026

Machine learning (ML) is transforming gas-separation membrane research, yet high retrospective accuracy does not necessarily translate into experimentally viable or process-relevant materials. This review reframes the field around the evidence chain...

(This article belongs to the Special Issue Next-Generation Gas Separation Membranes: Reticular Chemistry, Functional Fillers, and Scalable Fabrication)
  • Article
  • Open Access
436 Views
24 Pages

Identifiability Limits of Forward-Osmosis Membrane Transport from Water and Reverse-Solute Flux Observations

  • Maurizio Viviani,
  • Nicola Bragazzi,
  • Simonetta Papa,
  • Luca Giacomelli and
  • Roberto Eggenhöffner

13 October 2026

Forward osmosis (FO) membrane performance is commonly described through water flux Jw, reverse-solute flux Js, and the specific reverse-solute ratio RJ = Js/Jw. These observables provide a low-dimensional projection of a coupled transport system wher...

(This article belongs to the Special Issue Advances in Osmotic Membrane Process Modulation: Innovative Multiphysics Approaches)
  • Article
  • Open Access
480 Views
14 Pages

Characterization of In Vitro Performance and Hemocompatibility of a Novel Hemofilter for Continuous Kidney Replacement Therapy

  • Adam M. Zawada,
  • Lukas Theis,
  • Robert Nitschel,
  • Karlee Emal and ,
  • Robert Pohlmeier,
  • Skyler Boyington and
  • Ansgar Erlenkoetter
  • + 2 authors+ 0 author

12 October 2026

Performance and hemocompatibility are the main focus areas in the development of new hemofilters for continuous kidney replacement therapy. The novel multiFlux hemofilter features a polysulfone membrane with increased hydrophilicity to improve perfor...

(This article belongs to the Special Issue Recent Advances in Polymeric Membranes—Preparation and Applications (2nd Edition))
  • Article
  • Open Access
523 Views
13 Pages

Graphene Oxide (GO)/Polyamide Thin-Film Nanocomposite Membranes for Enhanced Pervaporation Desalination: Role of GO in Microstructural Modification and Water Transport

  • Yi Chen,
  • Yuxuan Li,
  • Yaoli Guo,
  • Xiaolong Xie and ,
  • Pengwei Huang,
  • Weini Chen and
  • Shengchao Zhao
  • + 2 authors+ 0 author

11 October 2026

Pervaporation (PV) desalination offers a viable route for high-salinity wastewater treatment, yet its broader implementation is constrained by limited membrane permeability. In this study, graphene oxide (GO)/polyamide (PA) thin-film nanocomposite (T...

(This article belongs to the Special Issue Membrane Materials and Technologies for Sustainable Water Treatment)
  • Article
  • Open Access
261 Views
24 Pages

10 October 2026

As coal mining intensity increases, the concentration of fine suspended solids (<10 μm) in mine water continues to rise. These particles carry a highly negative surface charge and interact synergistically with emulsified oil, making them diffic...

(This article belongs to the Section Membrane Applications for Water Treatment)
  • Article
  • Open Access
292 Views
25 Pages

Reactive Molecular Dynamics Simulations of Proton Transport in PFSA Membranes: Hydration–Temperature Mechanism Crossover and Cold-Start Implications

  • Haibin Lu,
  • Wanhua Qi,
  • Mingzhao Lai,
  • Hui Ye and ,
  • Taosif Iqbal,
  • Changchen Xie and
  • Yaoli Xu
  • + 2 authors+ 0 author

9 October 2026

Proton transport through perfluorosulfonic acid (PFSA) membranes sets the ohmic resistance of proton exchange membrane fuel cells and is most constrained during cold start, when reduced hydration coincides with sub-ambient temperatures, yet the condi...

(This article belongs to the Section Membrane Applications for Energy)
  • Review
  • Open Access
435 Views
23 Pages

Treatment of Azo Dye Wastewater by Anaerobic Membrane Bioreactors: A Review on Process Performance and Mitigation Strategies

  • Jia-Ning Chen,
  • Pengcheng Liu,
  • Hao Wu,
  • Xiang Li and ,
  • Zhe Kong,
  • Xueying Zhang and
  • Yong Hu
  • + 2 authors+ 0 author

7 October 2026

Membrane fouling and biological toxicity are two main bottlenecks in treating azo dye wastewater using anaerobic membrane bioreactors (AnMBRs). This review examines how azo dye molecular structure affects AnMBR performance and membrane fouling. It di...

(This article belongs to the Special Issue Membrane-Based Technologies for Nutrient Recovery: Materials, Mechanisms, and Integrated Processes)
  • Article
  • Open Access
499 Views
20 Pages

Low-Cost Ceramic Membrane with Concentrated Pore Size Distribution for Flue Gas Moisture Recovery

  • Tao Li,
  • Zheng Zhang,
  • Tengfei Li,
  • Jiguang Huang and ,
  • Heng Zhang and
  • Haiping Chen
  • + 1 author+ 0 author

4 October 2026

Transport membrane condenser with ceramic membrane has been proven to be effective in recovering water from industrial flue gas. A concentrated pore size distribution of the ceramic membrane assures high recovery performance and water quality. In thi...

(This article belongs to the Special Issue Ceramic Membranes in Harsh Gas Environments: Exploring the Potential for Practical Applications)
  • Review
  • Open Access
499 Views
22 Pages

3 October 2026

The development of novel hemodialysis membranes aims not only to enhance dialysis efficiency but also to improve hemocompatibility, an important determinant of treatment safety and tolerability. This narrative review provides a comprehensive overview...

  • Review
  • Open Access
460 Views
41 Pages

Membrane-Based Solar-Powered Brackish Water Treatment for Pastoral Livestock Watering in Arid Kazakhstan: A Techno-Economic Decision Framework

  • Timur Sh. Ustabaev,
  • Gulzhan S. Alimbetova,
  • Bakhtiyar Zh. Ismailov,
  • Berik M. Zhaksybek and ,
  • Ivan V. Basmanov,
  • Anar Z. Batynova and
  • Marzhan S. Kalmakhanova
  • + 2 authors+ 0 author

2 October 2026

Access to safe water at pastoral watering points constrains livestock productivity across Kazakhstan’s extensive pasturelands, many of which remain underused because of inadequate water infrastructure. This review presents a decision framework...

(This article belongs to the Special Issue Advanced Multifunctional Membranes for Sustainable Water–Energy–Resource Nexus)
  • Article
  • Open Access
809 Views
20 Pages

2 October 2026

Plasmid DNA (pDNA) is a key raw material for advanced therapeutic modalities, including gene therapy, mRNA production, and DNA vaccination, requiring efficient and scalable downstream processing strategies. Increasing demand places stringent requirem...

(This article belongs to the Section Membrane Applications for Other Areas)
  • Article
  • Open Access
1 Citations
499 Views
21 Pages

30 September 2026

Feed spacers can promote membrane-side transport in flat-sheet ultrafiltration channels, but the accompanying hydraulic resistance increases pumping demand. This study combined pure-water pressure-drop measurements with transient three-dimensional AN...

(This article belongs to the Section Membrane Applications for Water Treatment)
  • Article
  • Open Access
542 Views
18 Pages

30 September 2026

Reverse osmosis (RO) digital twins require predictive models whose accuracy remains credible as plant operating conditions change. We evaluated the readiness of predictive models for a full-scale, two-stage RO plant using operational spreadsheets and...

(This article belongs to the Section Membrane Applications for Water Treatment)
  • Article
  • Open Access
711 Views
17 Pages

VHH-Functionalized Silica-Coated Magnetic Nanoparticles for Immunoaffinity Isolation of Extracellular Vesicles

  • Jovana Terzić,
  • Lidija Filipović,
  • Ninoslav Mitić,
  • Sanja Stevanović and ,
  • Ario de Marco and
  • Milica Popović
  • + 1 author+ 0 author

29 September 2026

Extracellular vesicles (EVs) are membrane-enclosed nanoparticles involved in intercellular communication and numerous physiological and pathological processes. Their molecular cargo reflects the state of the cell of origin, making EVs promising sourc...

(This article belongs to the Section Biological Membranes)
  • Article
  • Open Access
454 Views
21 Pages

29 September 2026

The cathode catalyst layer (CL) is a key component governing the performance of proton exchange membrane fuel cells (PEMFCs), yet the trade-off between oxygen transport and electrochemical activity in conventional uniform CLs remains a critical limit...

  • Article
  • Open Access
407 Views
25 Pages

29 September 2026

Membrane fouling limits pressure-driven filtration by increasing hydraulic resistance and cleaning demand. Here, an external lead zirconate titanate actuator (PZT) was coupled to a passive polytetrafluoroethylene (PTFE) microfiltration membrane to ex...

(This article belongs to the Topic Separation Techniques and Circular Economy)
  • Article
  • Open Access
385 Views
31 Pages

28 September 2026

The rapid growth of lithium-ion battery (LIB) manufacturing has increased the generation of wastewater containing lithium and transition metals, creating a need for selective recovery processes with minimal chemical use. This study evaluated membrane...

(This article belongs to the Special Issue Membrane Materials and Technologies for Sustainable Water Treatment)
  • Article
  • Open Access
393 Views
15 Pages

28 September 2026

We characterized the structural determinants of phospholamban (PLB) and sarcolipin (SLN) self-assembly, using experimental and computational assays. PLB and SLN are transmembrane peptides that regulate contractility via phosphorylation-dependent regu...

(This article belongs to the Special Issue Biomolecular Interactions with Cell and Model Membranes: Integrating Biophysical Experiments and Computational Simulations)
  • Article
  • Open Access
331 Views
22 Pages

Rapid Screening and Analysis of Putative Bioactive Candidates in Zhizhu Decoction Using Membrane-Based Affinity Ultrafiltration-Mass Spectrometry

  • Shujun Wang,
  • Renai Fu,
  • Xiaowen Hua,
  • Yongbing Xu and ,
  • Yingying Zhang and
  • Mingquan Guo
  • + 1 author+ 0 author

27 September 2026

The Zhizhu Decoction (ZZD), as a classic traditional Chinese medicine prescription, has long served as an effective treatment for obesity. However, rapid analysis of its putative bioactive components and their mechanisms of action remains a challengi...

(This article belongs to the Section Biological Membranes)
  • Article
  • Open Access
613 Views
15 Pages

27 September 2026

Scaled-down ultrafiltration systems are frequently needed at various stages of protein biologics product and process development. In this paper, an economical and easy-to-use scaled-down tangential flow filtration (TFF) system that is suitable for co...

(This article belongs to the Special Issue Applications of Membrane Filtration and Separation)
  • Article
  • Open Access
1 Citations
486 Views
32 Pages

26 September 2026

Carbon dioxide (CO2) emissions are a major driver of global climate change, creating an urgent need for efficient carbon capture technologies. Gas–liquid membrane contactors (GLMCs) offer high interfacial area and operational flexibility, but m...

(This article belongs to the Section Membrane Applications for Gas Separation)
  • Article
  • Open Access
306 Views
21 Pages

NanoConfinementChat: A Domain-Specific Large Language Model for Mechanistic Interpretation of Nanoconfined Water and Ion Transport in Membrane Nanochannels

  • Shuhan Liu,
  • Yao He,
  • Youyang Liu,
  • Ziyi Yan and ,
  • Xinyu Zhang,
  • Yuxin Xiao,
  • Zhen Li and
  • Ning Wei
  • + 3 authors+ 0 author

26 September 2026

Nanoconfined water and ion transport determines permeability and selectivity in membrane nanochannels, yet the relevant mechanisms are dispersed across material systems, molecular simulations, and theoretical studies, hindering systematic mechanism-o...

(This article belongs to the Section Membrane Applications for Water Treatment)
  • Article
  • Open Access
337 Views
25 Pages

25 September 2026

High clean-water throughput does not necessarily translate into rapid fermentation-broth filtration. We hypothesized that a macroporous upstream layer combined with an asymmetric polyethersulfone (PES) membrane could unite rapid filtration at low bro...

(This article belongs to the Special Issue Advances in Bioinspired Membranes for Biomedical Applications)
  • Article
  • Open Access
254 Views
11 Pages

25 September 2026

Ultrafiltration membranes are widely used in wastewater reuse systems, but membrane fouling caused by effluent organic matter (EfOM) remains a major limitation. In this study, electrocatalytic oxidation (EO) was applied as a pretreatment strategy to...

(This article belongs to the Special Issue Membrane Fouling and Antifouling Strategies for Water and Wastewater Treatment)
  • Article
  • Open Access
305 Views
19 Pages

Multicomponent Modification of Polyethylene-Based Films for Enhanced Hydrophobicity and Balanced Gas Transport and Water Vapor Barrier Properties

  • Lijing Duan,
  • Shuaiqi Fang,
  • Leying Sun,
  • Yawen Wang and ,
  • Haobo Xiu,
  • Huabin Wang,
  • Abin Chen,
  • Baoxiu Wang,
  • Shiqiang Song and
  • Zhenlin Jiang
  • + 5 authors+ 0 author

25 September 2026

Hydrophobic gas-permeable polyethylene films with balanced water vapor resistance and gas transport properties are desirable for membrane applications; however, achieving an effective balance between moisture barrier performance and gas permeability...

  • Article
  • Open Access
437 Views
31 Pages

Biomimetic ADME Profiling of Multifunctional Biphenylalkoxyamine-Related Histamine H3 Receptor Ligands with Anti-Alzheimer Potential

  • Stefan Simić,
  • Dorota Łażewska,
  • Predrag Kalaba,
  • Judith Wackerlig-Damle and
  • Thierry Langer

25 September 2026

Multifunctional histamine H3 receptor (H3R) ligands with cholinesterase inhibitory activity are being explored as potential Alzheimer’s disease therapeutics, but their interactions with biological membranes and associated ADME properties requir...

(This article belongs to the Special Issue Drug Permeability Across Biological and Biomimetic Membranes: From Simple Models to Combination Therapy and Digital Twins in Precision Medicine)
  • Article
  • Open Access
401 Views
19 Pages

Mitigation of Delamination Between Bilayer Membranes with Low Affinity to Enable Roll-to-Roll Fabrication

  • Minwoo Jung,
  • Eesh M. Kulshrestha,
  • Isabel C. Escobar and
  • Tequila A. L. Harris

25 September 2026

Single-layer membranes, despite their ease of fabrication and performance, often face material characteristic limitations that are employed for membrane fabrication, such as polymer fouling propensity and low mechanical strength. To mitigate such mat...

(This article belongs to the Collection Polymeric Membranes: Science, Materials and Applications)
  • Article
  • Open Access
400 Views
31 Pages

24 September 2026

Even though vacuum membrane distillation (VMD) for low-temperature desalination is an innovative technology, industrial applications remain limited by the concentration and thermal polarization, and conventional passive spacers mitigate these issues...

  • Article
  • Open Access
400 Views
19 Pages

24 September 2026

We investigate the dynamics of two-dimensional multicomponent vesicles in confined Poiseuille flow, focusing on the interplay among membrane composition, mechanical heterogeneity, and hydrodynamic confinement. The membrane composition is described by...

(This article belongs to the Special Issue Advances in Biomembrane Structure, Dynamics, and Function)
  • Review
  • Open Access
396 Views
20 Pages

Membrane-Enabled Dialysate Regeneration for Wearable and Miniaturized Artificial Kidney Systems: Transport Requirements, Hybrid Architectures, and Translational Constraints

  • Yiqin Gan,
  • Jingying Zhou,
  • Chiwa Ao-Ieong,
  • Shouping Zhu and ,
  • Yihan Wang,
  • Chen Yun,
  • Xiaofan He,
  • Lianghong Yin,
  • Wenjie Ye and
  • Xianggeng Chi
  • + 6 authors+ 1 author

24 September 2026

Low-volume dialysate recirculation couples the primary dialysis membrane to the regeneration circuit in wearable and miniaturized artificial kidneys. This narrative review examines membranes as blood–dialysate barriers, fractionation devices, a...

  • Article
  • Open Access
452 Views
25 Pages

23 September 2026

Agricultural drainage water is a saline return flow whose reuse is constrained in intensively cultivated basins such as the Harran Plain in southeastern Türkiye. This exploratory, descriptive bench study examined microfiltration (MF) pretreatmen...

(This article belongs to the Section Membrane Applications for Water Treatment)
  • Communication
  • Open Access
685 Views
10 Pages

23 September 2026

Using membranes with recombination catalyst layers in PEM water electrolyzers effectively reduces the formation of explosive gas mixtures. Slot die coating is an established method for producing such functional layer systems. This work demonstrates t...

(This article belongs to the Special Issue Advanced Membranes for Hydrogen Energy Systems: Fuel Cells and Electrolyzers)
  • Article
  • Open Access
384 Views
16 Pages

22 September 2026

Plantago asiatica L. (P. asiatica) is traditionally used to treat diarrhoea in veterinary medicine, but its molecular basis remains unclear. In rodent models, the water extract and active fractions reduced intestinal fluid accumulation without signif...

(This article belongs to the Special Issue Computational and Mechanistic Insights into Cell Membrane-Targeted Drug Delivery)
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Membranes - ISSN 2077-0375