Antioxidants, Volume 7, Issue 8 (August 2018) – 14 articles
Cover Story (view full-size image): The cytokine IL-1β, depending on the context, can contribute to neural injury as well as participate in neuroprotection/repair. We describe data demonstrating the ability of IL-1β to protect neural cells in vitro against reactive oxygen species, initiated by the addition of tert-butyl hydroperoxide (t-BOOH), involves an increase in the production/release of astrocyte glutathione (depicted in schema; created with BioRender). These protective effects were not strictly an in vitro phenomenon as we found that endogenous IL1-β signaling protects against 3-nitropropionic acid-mediated oxidative stress in vivo. View Paper here.
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