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Brain Sciences, Volume 12, Issue 10

October 2022 - 156 articles

Cover Story: Many people with Alzheimer’s disease (AD) manifest a lack of motivation, i.e., apathy. A pathophysiological model of AD-related apathy proposed that this symptom may be a consequence of alterations in neural circuits involved in decision making and reward, encompassing primarily frontal, subcortical and brainstem areas. Previous studies have shown that apathy in AD may be primarily explained by functional alterations across salience and fronto-parietal networks, as well as by white matter damage, rather than an excess of grey matter neurodegeneration. In this study, we compared measures of both macro- and micro-structural white matter integrity between groups of patients with AD and healthy controls to support the hypothesis that structural disconnection may drive a lack of motivation. View this paper
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Articles (156)

  • Article
  • Open Access
6 Citations
3,342 Views
14 Pages

Effect of Blood Transfusion on Cerebral Hemodynamics and Vascular Topology Described by Computational Fluid Dynamics in Sickle Cell Disease Patients

  • Russell P. Sawyer,
  • Sirjana Pun,
  • Kristine A. Karkoska,
  • Cherita A. Clendinen,
  • Michael R. DeBaun,
  • Ephraim Gutmark,
  • Riccardo Barrile and
  • Hyacinth I. Hyacinth

18 October 2022

The main objective of this study was to demonstrate that computational fluid dynamics (CFD) modeling can be used to study the contribution of covert and overt vascular architecture to the risk for cerebrovascular disease in sickle cell disease (SCD)...

  • Article
  • Open Access
1 Citations
3,918 Views
14 Pages

17 October 2022

Number–color synesthesia is a condition in which synesthetes perceive numbers with concurrent experience of specific, corresponding colors. It has been proposed that synesthetic association exists primarily between representations of Arabic dig...

  • Article
  • Open Access
7 Citations
3,596 Views
14 Pages

Inter-Individual Variability in Motor Output Is Driven by Recruitment Gain in the Corticospinal Tract Rather Than Motor Threshold

  • Arkaprovo Sarkar,
  • Alish Dipani,
  • Giorgio Leodori,
  • Traian Popa,
  • Panagiotis Kassavetis,
  • Mark Hallett and
  • Nivethida Thirugnanasambandam

17 October 2022

Variability in the response of individuals to various non-invasive brain stimulation protocols is a major problem that limits their potential for clinical applications. Baseline motor-evoked potential (MEP) amplitude is the key predictor of an indivi...

  • Article
  • Open Access
10 Citations
5,637 Views
11 Pages

Phase Lag Index of Resting-State EEG for Identification of Mild Cognitive Impairment Patients with Type 2 Diabetes

  • Yuxing Kuang,
  • Ziyi Wu,
  • Rui Xia,
  • Xingjie Li,
  • Jun Liu,
  • Yalan Dai,
  • Dan Wang and
  • Shangjie Chen

17 October 2022

Mild cognitive impairment (MCI) is one of the important comorbidities of type 2 diabetes mellitus (T2DM). It is critical to find appropriate methods for early diagnosis and objective assessment of mild cognitive impairment patients with type 2 diabet...

  • Article
  • Open Access
14 Citations
3,905 Views
26 Pages

Interoception in Old Age

  • Gili Ulus and
  • Daniela Aisenberg-Shafran

17 October 2022

Emotion regulation in old age was found to be more efficient; seniors seem to focus less on the negative aspects of experiences. Here, we ask, do older individuals regulate their emotions more efficiently or are they numb to the physiological changes...

  • Article
  • Open Access
4 Citations
2,080 Views
8 Pages

Increased Proximal Wall Shear Stress of Basilar Artery Plaques Associated with Ruptured Fibrous Cap

  • Ruiyun Huang,
  • Hongbing Chen,
  • Chenghao Li,
  • Chaowei Lie,
  • Zhihua Qiu and
  • Yongjun Jiang

17 October 2022

Plaque rupture of the basilar artery is one of the leading causes of posterior circulation stroke. The present study aimed to investigate the role of fluid dynamics in the ruptured fibrous cap of basilar artery plaques. Patients with basilar artery p...

  • Article
  • Open Access
3 Citations
3,455 Views
11 Pages

Adherence and Reactogenicity to Vaccines against SARS-COV-2 in 285 Patients with Neuropathy: A Multicentric Study

  • Salvatore Iacono,
  • Vincenzo Di Stefano,
  • Paolo Alonge,
  • Claudia Vinciguerra,
  • Giammarco Milella,
  • Francesca Caputo,
  • Piergiorgio Lasorella,
  • Gabriele Neto,
  • Antonia Pignolo and
  • Angelo Torrente
  • + 8 authors

16 October 2022

Background: The safety of the new vaccines against SARS-CoV-2 have already been shown, although data on patients with polyneuropathy are still lacking. The aim of this study is to evaluate the adherence to SARS-CoV-2 vaccination, as well as the react...

  • Article
  • Open Access
1 Citations
3,107 Views
15 Pages

15 October 2022

The brain is susceptible to perturbations of redox balance, affecting neurogenesis and increasing the risks of psychiatric disorders. Thioredoxin-interacting protein (TXNIP) is an endogenous inhibitor of the thioredoxin antioxidant system. Its deleti...

  • Article
  • Open Access
13 Citations
4,109 Views
17 Pages

15 October 2022

Brain decoding is to predict the external stimulus information from the collected brain response activities, and visual information is one of the most important sources of external stimulus information. Decoding functional magnetic resonance imaging...

  • Article
  • Open Access
5 Citations
2,641 Views
11 Pages

The Efficacy and Tolerability of Electroconvulsive Therapy in Psychiatric Patients with Arachnoid Cysts: A Retrospective Chart Study

  • Ying Lu,
  • Yu Tian,
  • Yu Gan,
  • Yixiao Fu,
  • Qibin Chen,
  • Lei Zou,
  • Bangshu Zhao,
  • Yu Yan,
  • Shudong Liu and
  • Xiaolu Chen
  • + 1 author

15 October 2022

Electroconvulsive therapy (ECT) is an effective therapy for many psychiatric illnesses. However, intracranial occupying lesions are a relative contraindication to ECT. Arachnoid cysts are benign, congenital, and space-occupying lesions. Our study aim...

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Brain Sci. - ISSN 2076-3425