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Applied Sciences, Volume 10, Issue 18

September-2 2020 - 483 articles

Cover Story: The capability of emodin to prevent the interaction between the coronavirus’s spike protein and its human target receptor was proven 10 years ago, though the underpinning molecular mechanisms were not clearly described. This lack of knowledge prevents the rational use of emodin and related compounds to develop molecules that efficiently prevent viral infection. Our study provided a mechanistic rationale and the plausible mechanism of action of emodin is described as an interaction at the protein–protein interface that destabilizes the viral protein–target receptor complex. This knowledge-based foothold could provide a solid basis for the potential development of efficient antiviral cognate compounds. View this paper
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Articles (483)

  • Article
  • Open Access
5 Citations
4,240 Views
14 Pages

22 September 2020

At present, there is no clear understanding of the influence of differences in soil mineral composition, particle size grading, and hydraulic paths on the shear strength of unsaturated soil, and the related strength models are not applicable. The she...

  • Article
  • Open Access
16 Citations
4,494 Views
17 Pages

A New Architectural Approach to Monitoring and Controlling AM Processes

  • Muhammad Adnan,
  • Yan Lu,
  • Albert Jones,
  • Fan-Tien Cheng and
  • Ho Yeung

22 September 2020

The abilities to both monitor and control additive manufacturing (AM) processes in real-time are necessary before the routine production of quality AM parts will be possible. Currently, neither ability exist! The major reason is that AM processes are...

  • Article
  • Open Access
3 Citations
4,004 Views
19 Pages

Precoded Generalized Spatial Modulation for Downlink MIMO Transmissions in Beyond 5G Networks

  • João Pedro Pavia,
  • Vasco Velez,
  • Bernardo Brogueira,
  • Nuno Souto and
  • Américo Correia

22 September 2020

The design of multiple input multiple output (MIMO) schemes capable of achieving both high spectral and energy efficiency constitutes a challenge for next-generation wireless networks. MIMO schemes based on generalized spatial modulations (GSM) have...

  • Article
  • Open Access
8 Citations
3,538 Views
28 Pages

Measuring Quality of Service in a Robotized Comprehensive Geriatric Assessment Scenario

  • Adrián Romero-Garcés,
  • Jesús Martínez-Cruz,
  • Juan F. Inglés-Romero,
  • Cristina Vicente-Chicote,
  • Rebeca Marfil and
  • Antonio Bandera

22 September 2020

Comprehensive Geriatric Assessment (CGA) is an integrated clinical process to evaluate frail elderly people in order to create therapy plans that improve their quality and quantity of life. The whole process includes the completion of standardized qu...

  • Article
  • Open Access
12 Citations
10,839 Views
21 Pages

22 September 2020

The noise prediction using machine learning is a special study that has recently received increased attention. This is particularly true in workplaces with noise pollution, which increases noise exposure for general laborers. This study attempts to a...

  • Article
  • Open Access
10 Citations
7,542 Views
16 Pages

22 September 2020

Touchless interaction with electronic devices using gestures is gaining popularity and along with speech-based communication offers their users natural and intuitive control methods. Now, these interaction modes go beyond the entertainment industry a...

  • Article
  • Open Access
23 Citations
4,550 Views
15 Pages

Microseismic Signal Denoising and Separation Based on Fully Convolutional Encoder–Decoder Network

  • Hang Zhang,
  • Chunchi Ma,
  • Veronica Pazzi,
  • Yulin Zou and
  • Nicola Casagli

22 September 2020

Denoising methods are a highly desired component of signal processing, and they can separate the signal of interest from noise to improve the subsequent signal analyses. In this paper, an advanced denoising method based on a fully convolutional encod...

  • Article
  • Open Access
25 Citations
6,924 Views
22 Pages

22 September 2020

During the operation of open-pit mining, the loading position of a haulage truck often changes, bringing a new challenge concerning how to plan an optimal truck transportation path considering the terrain factors. This paper proposes a path planning...

  • Article
  • Open Access
18 Citations
3,602 Views
18 Pages

22 September 2020

Underground coal mining-induced ground subsidence (or major ground vertical settlement) is a major concern to the mining industry, government and people affected. Based on the probability integral method, this paper presents a new ground subsidence p...

  • Article
  • Open Access
4 Citations
2,721 Views
15 Pages

22 September 2020

An image recognition technique is proposed for determining optimal neck levels for standard metal gauges, in the process of validating pipe provers. A camera-level follow-up control system was designed to achieve automated tracking of fluid levels by...

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Appl. Sci. - ISSN 2076-3417