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Journal of Personalized Medicine, Volume 14, Issue 3

March 2024 - 110 articles

Cover Story: Sepsis is one of the most common causes of morbidity and mortality worldwide. Despite the remarkable advances in modern medicine throughout the last century, the mortality rates associated with sepsis have remained significantly elevated, both in high- and low-income countries. The main difficulty in the diagnosis and treatment of septic patients is the tremendous heterogeneity of this condition. The vast heterogeneity that characterizes sepsis ranges from its clinical presentation to the biological aspects of the disease. Evidence-based medicine approaches sepsis as a homogenous syndrome and does not consider the individual discrepancies between septic patients. This approach may contribute to the poor outcomes of such patients. In recent years, personalized medicine has gained significant interest. View this paper
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Articles (110)

  • Article
  • Open Access
1,439 Views
14 Pages

Functional Status Correlates of Change and Stability in Appraisal after Spine Surgery: Earlier versus Later Effects

  • Carolyn E. Schwartz,
  • Katrina Borowiec,
  • Bruce D. Rapkin and
  • Joel A. Finkelstein

21 March 2024

Spine surgery generally yields a notable improvement in patients’ health state, and there is variability in measured patient outcomes after spine surgery. The present work aimed to describe for clinicians how appraisal underlies their patients&...

  • Article
  • Open Access
12 Citations
2,527 Views
23 Pages

Concatenated Modified LeNet Approach for Classifying Pneumonia Images

  • Dhayanithi Jaganathan,
  • Sathiyabhama Balsubramaniam,
  • Vidhushavarshini Sureshkumar and
  • Seshathiri Dhanasekaran

21 March 2024

Pneumonia remains a critical health concern worldwide, necessitating efficient diagnostic tools to enhance patient care. This research proposes a concatenated modified LeNet classifier to classify pneumonia images accurately. The model leverages deep...

  • Review
  • Open Access
7 Citations
10,368 Views
18 Pages

Prophylactic Antibiotics before Gynecologic Surgery: A Comprehensive Review of Guidelines

  • Stamatios Petousis,
  • Panagiota Angelou,
  • Aristarchos Almperis,
  • Antonio Simone Laganà,
  • Gerasimos Titilas,
  • Chrysoula Margioula-Siarkou and
  • Konstantinos Dinas

21 March 2024

Surgical site infections (SSIs) refer to infections in the incision, organ, or postoperative space. As common healthcare-associated infections, SSIs correlate with prolonged hospital stay, additional procedures, ICU stay, and higher mortality rates....

  • Review
  • Open Access
3 Citations
4,067 Views
14 Pages

Oxygen–Ozone Therapy of Musculoskeletal Neck Pain: A Review

  • Jiri Jandura,
  • Milan Vajda,
  • Michal Cech and
  • Pavel Ryska

21 March 2024

Minimally invasive oxygen–ozone (O2-O3) therapy utilizing the biochemical effects of O2-O3 mixture is commonly used in the treatment of musculoskeletal pain. The literature dealing with O2-O3 therapy of spinal pain focuses mainly on the lumbosa...

  • Article
  • Open Access
2,578 Views
12 Pages

Clinical Variables and Peripheral Biomarkers Associated with Substance-Induced Psychotic Disorder: Differences Related to Alcohol, Cannabis, and Psychostimulant Abuse

  • Martina Di Paolo,
  • Antonia Calabrese,
  • Guido Nosari,
  • Valentina Ciappolino,
  • Luisa Cirella,
  • Alice Caldiroli,
  • Enrico Capuzzi,
  • Massimo Clerici and
  • Massimiliano Buoli

21 March 2024

Background: The present retrospective observational study aims to identify differences in clinical features and peripheral biomarkers among patients affected by substance-induced psychotic disorder (SIPD) according to the primary substance of abuse....

  • Article
  • Open Access
1 Citations
1,753 Views
14 Pages

Assessment of a New Medical Device (PirifixTM) for Positioning and Maintaining the Upper Dental Arch during Le Fort I Osteotomy

  • Pierre-Etienne Serree,
  • Eugénie Bertin,
  • Camille Coussens,
  • Eleonore Brumpt,
  • Jean-François Devoti and
  • Aurélien Louvrier

20 March 2024

Introduction: Several medical devices (MDs) are used to assist surgeons in positioning the upper dental arch (UDA) during Le Fort I osteotomies (LFIOs). Some only allow holding, others only positioning. This study aimed to assess the accuracy of a ne...

  • Article
  • Open Access
1 Citations
3,486 Views
13 Pages

20 March 2024

The African continent has the highest prevalence of hypertension globally, with South Africa reporting the highest prevalence in Southern Africa. While the influence of genetic variability in the pathogenesis of hypertension is well described interna...

  • Review
  • Open Access
3 Citations
2,584 Views
24 Pages

Exploring Costimulatory Blockade-Based Immunologic Strategies in Transplantation: Are They a Promising Immunomodulatory Approach for Organ and Vascularized Composite Allotransplantation?

  • Andreea Grosu-Bularda,
  • Florin-Vlad Hodea,
  • Dragos Zamfirescu,
  • Alexandru Stoian,
  • Răzvan Nicolae Teodoreanu,
  • Ioan Lascăr and
  • Cristian Sorin Hariga

20 March 2024

The field of transplantation, including the specialized area of vascularized composite allotransplantation (VCA), has been transformed since the first hand transplant in 1998. The major challenge in VCA comes from the need for life-long immunosuppres...

  • Article
  • Open Access
2 Citations
2,384 Views
15 Pages

Characterization of Plastic Scintillator Detector for In Vivo Dosimetry in Gynecologic Brachytherapy

  • Antonio Herreros,
  • José Pérez-Calatayud,
  • Facundo Ballester,
  • Rosa Abellana,
  • Joana Neves,
  • Joana Melo,
  • Luis Moutinho,
  • Jordi Tarrats-Rosell,
  • Sergi Serrano-Rueda and
  • Luca Tagliaferri
  • + 2 authors

20 March 2024

(1) Background: High dose gradients and manual steps in brachytherapy treatment procedures can lead to dose errors which make the use of in vivo dosimetry (IVD) highly recommended for verifying brachytherapy treatments. A new procedure was presented...

  • Article
  • Open Access
2 Citations
2,004 Views
11 Pages

Influence of Pelvic Floor Disorders on Sleep Quality in Women

  • Rocío Adriana Peinado-Molina,
  • Sergio Martínez-Vázquez,
  • Antonio Hernández-Martínez and
  • Juan Miguel Martínez-Galiano

20 March 2024

Pelvic floor disorders, the impact of their symptoms, and their association with sleep quality and sleep disorders is a little studied area. The aim of this study was to determine if an association exists between pelvic floor disorders in women and s...

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J. Pers. Med. - ISSN 2075-4426Creative Common CC BY license