Journal of Personalized Medicine, Volume 13, Issue 10
October 2023 - 99 articles
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Cover Story: Patients with systemic sclerosis (SSc) are at risk of diaphragmatic dysfunction because of multiple factors. This study aimed to evaluate diaphragmatic function by assessing ultrasonic parameters—mobility, thickness, and thickening fraction, with regard to interstitial lung disease (SSc-ILD)—and to investigate associations between ultrasonic parameters and the Modified Medical Research Council (mMRC) dyspnea scale, lung function, modified Rodnan skin score (mRSS), and esophageal diameters upon HRCT. Patients with SSc-ILD had lower diaphragmatic mobility in deep breathing than patients without ILD. The results demonstrated negative correlations between diaphragmatic mobility and the mMRC scale, mRSS, esophageal diameters, and a positive correlation with lung function. View this paper