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Diagnostics, Volume 13, Issue 3

2023 February-1 - 246 articles

Cover Story: Dried blood spots (DBSs) are a low-cost, non-invasive and convenient alternative to serum/plasma for serological and molecular testing. They can be easily obtained without the necessary equipment for venipuncture or the qualified healthcare personnel. Their use can be beneficial in low- and middle-income countries where it is difficult to obtain and test serum due to the lack of resources, and also in high-income countries to improve sampling by reaching patients not linked to the healthcare system. This manuscript evaluates the utility of DBSs to investigate mumps, measles and rubella IgG. In particular, our work summarizes the effect of hematocrit and different storage conditions (−20 °C, 4 °C and room temperature) for 4 months to perform serological diagnosis using an automated chemiluminescent immunoassay. View this paper
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Articles (246)

  • Interesting Images
  • Open Access
2 Citations
3,780 Views
5 Pages

In patients with thyroid nodules, if the cervical lymph nodes gradually enlarge, a histological confirmation is required to rule out malignancy. Here is a case of benign intranodal thyroid tissue with cystic changes resembling lymph node metastasis o...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
76 Citations
9,828 Views
16 Pages

A Medical Image Segmentation Method Based on Improved UNet 3+ Network

  • Yang Xu,
  • Shike Hou,
  • Xiangyu Wang,
  • Duo Li and
  • Lu Lu

In recent years, segmentation details and computing efficiency have become more important in medical image segmentation for clinical applications. In deep learning, UNet based on a convolutional neural network is one of the most commonly used models....

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Article
  • Open Access
6 Citations
4,952 Views
24 Pages

A Novel Automatic Audiometric System Design Based on Machine Learning Methods Using the Brain’s Electrical Activity Signals

  • Mustafa Küçükakarsu,
  • Ahmet Reşit Kavsaoğlu,
  • Fayadh Alenezi,
  • Adi Alhudhaif,
  • Raghad Alwadie and
  • Kemal Polat

This study uses machine learning to perform the hearing test (audiometry) processes autonomously with EEG signals. Sounds with different amplitudes and wavelengths given to the person tested in standard hearing tests are assigned randomly with the in...

(This article belongs to the Special Issue Application of Deep Learning in the Diagnosis of Brain Diseases)
  • Article
  • Open Access
6 Citations
4,075 Views
21 Pages

The virus responsible for COVID-19 is mutating day by day with more infectious characteristics. With the limited healthcare resources and overburdened medical practitioners, it is almost impossible to contain this virus. The automatic identification...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Review
  • Open Access
101 Citations
10,715 Views
27 Pages

Modern Methods of Diagnostics and Treatment of Neurodegenerative Diseases and Depression

  • Natalia Shusharina,
  • Denis Yukhnenko,
  • Stepan Botman,
  • Viktor Sapunov,
  • Vladimir Savinov,
  • Gleb Kamyshov,
  • Dmitry Sayapin and
  • Igor Voznyuk

This paper discusses the promising areas of research into machine learning applications for the prevention and correction of neurodegenerative and depressive disorders. These two groups of disorders are among the leading causes of decline in the qual...

(This article belongs to the Special Issue Medical Diagnostic Systems Based on Advancing Artificial Intelligence Concepts)
  • Case Report
  • Open Access
3 Citations
3,018 Views
6 Pages

Hyperammonemia can lead to encephalopathy and may be accompanied by a diagnostic dilemma. Imaging as well as biochemical analyses are the cornerstone for identifying possible underlying causes such as severe liver disease or urea cycle defect. We rep...

(This article belongs to the Special Issue Advances and Novelties in Hepatobiliary and Pancreatic Imaging 2.0)
  • Article
  • Open Access
5 Citations
8,419 Views
10 Pages

Changes in Artery Diameters and Fetal Growth in Cases of Isolated Single Umbilical Artery

  • Elena Contro,
  • Laura Larcher,
  • Jacopo Lenzi,
  • Marina Valeriani,
  • Antonio Farina and
  • Eric Jauniaux

Background—There are conflicting data in the international literature on the risks of abnormal fetal growth in fetuses presenting an isolated single umbilical artery (SUA), and the pathophysiology of this complication is poorly understood. Obje...

(This article belongs to the Special Issue Editorial Board Members' Collection Series: Advances in Gynecology and Obstetrics)
  • Article
  • Open Access
3 Citations
3,700 Views
11 Pages

The Use of 99mTc-Mononuclear Leukocyte Scintigraphy for Necrotizing External Otitis Diagnosis

  • Sergio Augusto Lopes de Souza,
  • Roberta Silveira Santos Laurindo,
  • Gabriel Gutfilen-Schlesinger,
  • Felippe Felix,
  • José Luiz de Medeiros Amarante Junior and
  • Bianca Gutfilen

Background: Necrotizing external otitis (NEO) is a severe infectious disease in the external acoustic meatus (EAM) and mastoid that may extend to the cranial base. Due to the lack of a gold standard examination technique, the diagnosis is often diffi...

(This article belongs to the Section Biomedical Optics)
  • Article
  • Open Access
5 Citations
2,570 Views
10 Pages

[18F]FDG PET-MR in the Evaluation and Follow-Up of Incidental Bone Ischemic Lesions in a Mono-Center Cohort of Pediatric Patients Affected by Hodgkin’s Lymphoma

  • Chiara Giraudo,
  • Elisa Carraro,
  • Elena Cavallaro,
  • Monica Zuliani,
  • Liliya Spampinato Gotsyak,
  • Davide Massano,
  • Antonella Modugno,
  • Lara Mussolin,
  • Alessandra Biffi and
  • Pietro Zucchetta
  • + 2 authors

Hodgkin’s lymphoma (HL) is one of the neoplasms with the best prognosis in children, adolescents and young adults, but sufferers are burdened by the possibility of developing adverse effects such as Bone Ischemic Lesions (BILs) which are lesion...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
4 Citations
2,771 Views
12 Pages

APOBEC3B Is Co-Expressed with PKCα/NF-κB in Oral and Oropharyngeal Squamous Cell Carcinomas

  • Galinos Fanourakis,
  • Efthymios Kyrodimos,
  • Vasileios Papanikolaou,
  • Aristeidis Chrysovergis,
  • Georgia Kafiri,
  • Nikolaos Papanikolaou,
  • Mihalis Verykokakis,
  • Konstantinos Tosios and
  • Heleni Vastardis

The enzymatic activity of APOBEC3B (A3B) has been implicated as a prime source of mutagenesis in head and neck squamous cell carcinoma (HNSCC). The expression of Protein Kinase C α (PKCα) and Nuclear Factor-κΒ p65 (NF-κ&B...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
14 Citations
4,149 Views
13 Pages

Tumor Lung Visualization and Localization through Virtual Reality and Thermal Feedback Interface

  • Samir Benbelkacem,
  • Nadia Zenati-Henda,
  • Nabil Zerrouki,
  • Adel Oulefki,
  • Sos Agaian,
  • Mostefa Masmoudi,
  • Ahmed Bentaleb and
  • Alex Liew

The World Health Organization estimates that there were around 10 million deaths due to cancer in 2020, and lung cancer was the most common type of cancer, with over 2.2 million new cases and 1.8 million deaths. While there have been advances in the...

(This article belongs to the Special Issue Leading Diagnosis on Chest Imaging)
  • Review
  • Open Access
15 Citations
3,979 Views
13 Pages

The Use of Endoscopic Ultrasonography in Inflammatory Bowel Disease: A Review of the Literature

  • Răzvan-Cristian Statie,
  • Dan Nicolae Florescu,
  • Dan-Ionuț Gheonea,
  • Bogdan Silviu Ungureanu,
  • Sevastița Iordache,
  • Ion Rogoveanu and
  • Tudorel Ciurea

The diagnosis of inflammatory bowel disease (IBD) can sometimes be challenging. By corroborating clinical, imaging and histological data, the two main entities of IBD, ulcerative colitis and Crohn’s disease (CD), can be differentiated in most c...

(This article belongs to the Special Issue Advances in Endoscopic Ultrasound)
  • Review
  • Open Access
28 Citations
5,153 Views
12 Pages

Potential Role of PSMA-Targeted PET in Thyroid Malignant Disease: A Systematic Review

  • Alessio Rizzo,
  • Manuela Racca,
  • Sara Dall’Armellina,
  • Roberto C. Delgado Bolton,
  • Domenico Albano,
  • Francesco Dondi,
  • Francesco Bertagna,
  • Salvatore Annunziata and
  • Giorgio Treglia

Background: Recently, several studies introduced the potential use of positron emission tomography/computed tomography (PET/CT) with prostate-specific membrane antigen (PSMA)-targeting radiopharmaceuticals in radioiodine-refractory thyroid cancer (TC...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
1 Citations
2,886 Views
12 Pages

PET/CT of the Spleen with Gallium-Oxine-Labeled, Heat-Damaged Red Blood Cells: Clinical Experience and Technical Aspects

  • Robert Drescher,
  • Philipp Seifert,
  • Sebastian Gröber,
  • Julia Greiser,
  • Christian Kühnel,
  • Falk Gühne and
  • Martin Freesmeyer

Several scintigraphic techniques have been supplemented or replaced by PET/CT methods because of their superior sensitivity, high resolution, and absolute activity quantification capability. The purpose of this project was the development of a PET tr...

(This article belongs to the Special Issue The Impact of PET/CT Imaging in Oncology)
  • Interesting Images
  • Open Access
5 Citations
3,517 Views
5 Pages

Acute Esophageal Necrosis in Acute Pancreatitis—Report of a Case and Endoscopic and Clinical Perspective

  • Monica Grigore,
  • Iulia Enache,
  • Mirela Chirvase,
  • Andrada Loredana Popescu,
  • Florentina Ionita-Radu,
  • Mariana Jinga and
  • Sandica Bucurica

Esophageal stroke, also known as acute esophageal necrosis or Gurvits syndrome, is an entity that has gained more and more recognition in the last two decades. It is also named “black esophagus” because of striking black discoloration of...

(This article belongs to the Special Issue Diagnosis and Prognosis of Gastrointestinal Diseases)
  • Review
  • Open Access
19 Citations
27,078 Views
14 Pages

Diffuse idiopathic skeletal hyperostosis (DISH) is a systemic condition characterized by new bone formation and enthesopathies of the axial and peripheral skeleton. The pathogenesis of DISH is not well understood, and it is currently considered a non...

(This article belongs to the Special Issue Diagnostic Imaging of Spinal Disorders)
  • Article
  • Open Access
57 Citations
7,407 Views
19 Pages

An Ensemble Model for the Diagnosis of Brain Tumors through MRIs

  • Ehsan Ghafourian,
  • Farshad Samadifam,
  • Heidar Fadavian,
  • Peren Jerfi Canatalay,
  • AmirReza Tajally and
  • Sittiporn Channumsin

Automatic brain tumor detection in MR Images is one of the basic applications of machine vision in medical image processing, which, despite much research, still needs further development. Using multiple machine learning techniques as an ensemble syst...

(This article belongs to the Special Issue Diagnosis of Brain Tumors)
  • Article
  • Open Access
10 Citations
4,774 Views
19 Pages

Evaluation and Analysis of Absence of Homozygosity (AOH) Using Chromosome Analysis by Medium Coverage Whole Genome Sequencing (CMA-seq) in Prenatal Diagnosis

  • Yan Lü,
  • Yulin Jiang,
  • Xiya Zhou,
  • Na Hao,
  • Guizhen Lü,
  • Xiangxue Guo,
  • Ruidong Guo,
  • Wenjie Liu,
  • Chenlu Xu and
  • Qingwei Qi
  • + 5 authors

Objective: Absence of homozygosity (AOH) is a genetic characteristic known to cause human diseases mainly through autosomal recessive or imprinting mechanisms. The importance and necessity of accurate AOH detection has become more clinically signific...

(This article belongs to the Special Issue Prenatal Diagnosis: Current Trends and Future Directions)
  • Review
  • Open Access
28 Citations
5,405 Views
16 Pages

SARS-CoV-2 Omicron (B.1.1.529) Variant: A Challenge with COVID-19

  • Zeinab Mohseni Afshar,
  • Ali Tavakoli Pirzaman,
  • Bardia Karim,
  • Shiva Rahimipour Anaraki,
  • Rezvan Hosseinzadeh,
  • Elaheh Sanjari Pireivatlou,
  • Arefeh Babazadeh,
  • Dariush Hosseinzadeh,
  • Seyed Rouhollah Miri and
  • Soheil Ebrahimpour
  • + 3 authors

Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, there have been multiple peaks of the SARS-CoV-2 (severe acute respiratory syndrome coronavirus virus 2) infection, mainly due to the emergence of new variants, each with a new...

(This article belongs to the Special Issue Monitoring and Detection for SARS-CoV-2 and Its Variants)
  • Article
  • Open Access
3 Citations
2,951 Views
12 Pages

Evaluation of the Efficacy of BBIBP-CorV Inactivated Vaccine Combined with BNT62b2 mRNA Booster Vaccine

  • Éva Rákóczi,
  • Gusztáv Magócs,
  • Sára Kovács,
  • Béla Nagy,
  • Gabriella Szűcs and
  • Zoltán Szekanecz

Objectives: In this prospective study, SARS-CoV−2 spike protein specific total immunoglobulin (Ig) levels were analyzed before and after BNT162 b2 mRNA booster vaccination in individuals previously administered with two doses of BBIBP-CorV vacc...

(This article belongs to the Section Diagnostic Microbiology and Infectious Disease)
  • Article
  • Open Access
25 Citations
6,980 Views
28 Pages

DTLCx: An Improved ResNet Architecture to Classify Normal and Conventional Pneumonia Cases from COVID-19 Instances with Grad-CAM-Based Superimposed Visualization Utilizing Chest X-ray Images

  • Md. Khabir Uddin Ahamed,
  • Md Manowarul Islam,
  • Md. Ashraf Uddin,
  • Arnisha Akhter,
  • Uzzal Kumar Acharjee,
  • Bikash Kumar Paul and
  • Mohammad Ali Moni

COVID-19 is a severe respiratory contagious disease that has now spread all over the world. COVID-19 has terribly impacted public health, daily lives and the global economy. Although some developed countries have advanced well in detecting and bearin...

(This article belongs to the Special Issue Chest X-ray Detection and Classification of Chest Abnormalities)
  • Article
  • Open Access
11 Citations
5,929 Views
13 Pages

Validation of a Deep Learning Model for Detecting Chest Pathologies from Digital Chest Radiographs

  • Pranav Ajmera,
  • Prashant Onkar,
  • Sanjay Desai,
  • Richa Pant,
  • Jitesh Seth,
  • Tanveer Gupte,
  • Viraj Kulkarni,
  • Amit Kharat,
  • Nandini Passi and
  • V. M. Kulkarni
  • + 1 author

Purpose: Manual interpretation of chest radiographs is a challenging task and is prone to errors. An automated system capable of categorizing chest radiographs based on the pathologies identified could aid in the timely and efficient diagnosis of che...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Systematic Review
  • Open Access
31 Citations
8,609 Views
28 Pages

Virtual Versus Light Microscopy Usage among Students: A Systematic Review and Meta-Analytic Evidence in Medical Education

  • Sabyasachi Maity,
  • Samal Nauhria,
  • Narendra Nayak,
  • Shreya Nauhria,
  • Tamara Coffin,
  • Jadzia Wray,
  • Sepehr Haerianardakani,
  • Ramsagar Sah,
  • Andrew Spruce and
  • Anil V. Parwani
  • + 7 authors

Background: The usage of whole-slide images has recently been gaining a foothold in medical education, training, and diagnosis. Objectives: The first objective of the current study was to compare academic performance on virtual microscopy (VM) and li...

(This article belongs to the Special Issue Digital Pathology: Records of Successful Implementations)
  • Article
  • Open Access
6 Citations
3,956 Views
11 Pages

The Role of Nasal Cytology and Serum Atopic Biomarkers in Paediatric Rhinitis

  • Giulia Dodi,
  • Paola Di Filippo,
  • Francesca Ciarelli,
  • Annamaria Porreca,
  • Fiorella Cazzato,
  • Lorena Matonti,
  • Sabrina Di Pillo,
  • Giampiero Neri,
  • Francesco Chiarelli and
  • Marina Attanasi

A Nasal Provocation Test allows the differentiation of allergic and non-allergic rhinitis, but it is difficult and expensive. Therefore, nasal cytology is taking hold as an alternative. We carried out a cross-sectional study, including 29 patients wi...

(This article belongs to the Section Clinical Laboratory Medicine)
  • Review
  • Open Access
18 Citations
5,426 Views
20 Pages

Cardiac Magnetic Resonance Imaging in Appraising Myocardial Strain and Biomechanics: A Current Overview

  • Alexandru Zlibut,
  • Cosmin Cojocaru,
  • Sebastian Onciul and
  • Lucia Agoston-Coldea

Subclinical alterations in myocardial structure and function occur early during the natural disease course. In contrast, clinically overt signs and symptoms occur during late phases, being associated with worse outcomes. Identification of such subcli...

(This article belongs to the Special Issue Advances in Cardiovascular Magnetic Resonance)
  • Article
  • Open Access
10 Citations
3,847 Views
12 Pages

Surface electromyography (EMG) allows reliable detection of muscle activity in all nine intrinsic and extrinsic ear muscles during facial muscle movements. The ear muscles are affected by synkinetic EMG activity in patients with postparalytic facial...

(This article belongs to the Special Issue Machine Learning in Signal and Image Analysis for Biomedical Application)
  • Article
  • Open Access
6 Citations
3,631 Views
14 Pages

The Additive Value of Radiomics Features Extracted from Baseline MR Images to the Barcelona Clinic Liver Cancer (BCLC) Staging System in Predicting Transplant-Free Survival in Patients with Hepatocellular Carcinoma: A Single-Center Retrospective Analysis

  • Mohammad Mirza-Aghazadeh-Attari,
  • Bharath Ambale Venkatesh,
  • Mounes Aliyari Ghasabeh,
  • Alireza Mohseni,
  • Seyedeh Panid Madani,
  • Ali Borhani,
  • Haneyeh Shahbazian,
  • Golnoosh Ansari and
  • Ihab R. Kamel

Background: To study the additive value of radiomics features to the BCLC staging system in clustering HCC patients. Methods: A total of 266 patients with HCC were included in this retrospective study. All patients had undergone baseline MR imaging,...

(This article belongs to the Special Issue Biomarkers in Diagnosis and Management of Hepatocellular Carcinoma)
  • Article
  • Open Access
113 Citations
12,697 Views
15 Pages

Medical Images Segmentation for Lung Cancer Diagnosis Based on Deep Learning Architectures

  • Yahia Said,
  • Ahmed A. Alsheikhy,
  • Tawfeeq Shawly and
  • Husam Lahza

Lung cancer presents one of the leading causes of mortalities for people around the world. Lung image analysis and segmentation are one of the primary steps used for early diagnosis of cancer. Handcrafted medical imaging segmentation presents a very...

(This article belongs to the Special Issue Cardiothoracic Imaging: Diagnostics and Modern Techniques)
  • Review
  • Open Access
22 Citations
10,253 Views
19 Pages

The prevalence of pancreatic cysts has been rising due to the widespread use of cross-sectional imaging (CT scan and MRI) of the abdomen. While most pancreatic cysts are benign and do not require treatment or surveillance, a significant minority are...

(This article belongs to the Special Issue Diagnosis and Management of Pancreatic Cysts)
  • Interesting Images
  • Open Access
2 Citations
3,954 Views
4 Pages

Delayed Aortic Valve Perforation Caused by Blunt Trauma

  • Kazuya Tateishi,
  • Chantal Y. Asselin,
  • Elie M. Elmann and
  • Joseph De Gregorio

Traumatic aortic regurgitation (AR) is a rare complication of blunt chest trauma. We described the case of a 35-year-old male who presented to our hospital with shortness of breath 7 years after sustaining blunt chest trauma associated with a motorcy...

(This article belongs to the Special Issue Thoracic Aortic Disease: From Bench to Bedside)
  • Article
  • Open Access
18 Citations
5,254 Views
15 Pages

Local-Ternary-Pattern-Based Associated Histogram Equalization Technique for Cervical Cancer Detection

  • Saravanan Srinivasan,
  • Aravind Britto Karuppanan Raju,
  • Sandeep Kumar Mathivanan,
  • Prabhu Jayagopal,
  • Jyothi Chinna Babu and
  • Aditya Kumar Sahu

Every year, cervical cancer is a leading cause of mortality in women all over the world. This cancer can be cured if it is detected early and patients are treated promptly. This study proposes a new strategy for the detection of cervical cancer using...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Article
  • Open Access
5 Citations
2,421 Views
9 Pages

The Association between Admission Serum Phosphorus and Preoperative Deep Venous Thrombosis in Geriatric Hip Fracture: A Retrospective Study

  • Dong-Xing Lu,
  • Kun Zhang,
  • Teng Ma,
  • Ming Li,
  • Zhong Li,
  • Yi-Bo Xu,
  • Chao-Feng Wang,
  • Cheng Ren and
  • Bin-Fei Zhang

Objective: This study aimed to evaluate the association between serum phosphorus level and preoperative deep vein thrombosis (DVT) in geriatric hip fractures. Methods: Older adults with hip fractures were screened between January 2015 and September 2...

(This article belongs to the Section Clinical Laboratory Medicine)
  • Article
  • Open Access
6 Citations
3,838 Views
11 Pages

Objective: To evaluate the stiffness of the sciatic nerve by shear wave elastography (SWE) and to determine whether SWE can be used to predict diabetic foot ulcer (DFU) in a patient with diabetic peripheral neuropathy (DPN). Methods: Sixteen patients...

(This article belongs to the Special Issue Ultrasound Imaging in Medicine 2023)
  • Article
  • Open Access
1 Citations
2,488 Views
13 Pages

Physiotherapists commonly use mobilizations for treating patients with thoracic spine pain (TSP). There is evidence to suggest that spinal mobilizations can decrease pain. Different doses of mobilization treatment are applied, however there is a pauc...

(This article belongs to the Section Point-of-Care Diagnostics and Devices)
  • Communication
  • Open Access
3 Citations
9,346 Views
8 Pages

Overlap of Suspicious and Non-Suspicious Features in the Ultrasound Evaluations of Leiomyosarcoma: A Single-Center Experience

  • Francesca Arezzo,
  • Gennaro Cormio,
  • Carmela Putino,
  • Nicola Di Lillo,
  • Erica Silvestris,
  • Anila Kardhashi,
  • Ambrogio Cazzolla,
  • Claudio Lombardi,
  • Michele Mongelli and
  • Vera Loizzi
  • + 1 author

Leiomyosarcoma (LMS) is a rare type of mesenchymal tumor. Suspecting LMS before surgery is crucial for proper patient management. Ultrasound is the primary method for assessing myometrial lesions. The overlapping of clinical, laboratory, as well as u...

(This article belongs to the Special Issue Imaging of Gynecological Disease 2.0)
  • Interesting Images
  • Open Access
2 Citations
6,851 Views
3 Pages

Diagnosis of Uric Acid-Based Urine Sedimentation in the Bladder Using Dual-Energy CT

  • Christian Booz,
  • Ibrahim Yel,
  • Julian L. Wichmann,
  • Simon S. Martin,
  • Vitali Koch,
  • Leon D. Gruenewald,
  • Leona S. Alizadeh,
  • Thomas J. Vogl and
  • Tommaso D’Angelo

Urine sedimentation in the bladder can occur in various circumstances and can lead to urinary obstruction/stasis with associated pain. It is usually diagnosed with an ultrasound; however, CT is also used to assess the amount and to further check for...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Review
  • Open Access
46 Citations
13,904 Views
12 Pages

Brain Tumor at Diagnosis: From Cognition and Behavior to Quality of Life

  • Daniela Pia Rosaria Chieffo,
  • Federica Lino,
  • Daniele Ferrarese,
  • Daniela Belella,
  • Giuseppe Maria Della Pepa and
  • Francesco Doglietto

Background: The present narrative review aims to discuss cognitive–emotional–behavioral symptoms in adults with brain tumors at the time of diagnosis. Methods: The PubMed database was searched considering glioma, pituitary adenoma, and me...

(This article belongs to the Special Issue Diagnosis of Brain Tumors)
  • Article
  • Open Access
6 Citations
2,661 Views
14 Pages

Several studies have demonstrated the difficulties in distinguishing malignant lesions of the breast from benign lesions owing to overlapping morphological features on ultrasound. Consequently, we aimed to develop a nomogram based on shear wave elast...

(This article belongs to the Special Issue Advanced Ultrasound Technologies for Diagnosis)
  • Interesting Images
  • Open Access
7 Citations
11,884 Views
2 Pages

Placenta Previa et Percreta: A Potentially Life-Threatening Condition

  • Cornelia Bachmann,
  • Harald Abele and
  • Markus Hoopmann

Placenta percreta occurs in about 5% of placenta accreta spectrum (PAS) and causes high maternal and fetal peripartum morbidity/mortality. A 34-year-old multiparous 4G2P (1xcesarean section (CS)) was admitted to hospital at the 34th week of gestation...

(This article belongs to the Special Issue Interesting Images in Obstetrics and Gynecology)
  • Review
  • Open Access
28 Citations
8,046 Views
14 Pages

A Review on Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of Pancreatic Lesions

  • Fred G. Karaisz,
  • Osama O. Elkelany,
  • Benjamin Davies,
  • Gerard Lozanski and
  • Somashekar G. Krishna

The morbidity associated with pancreatectomies limits surgical options for high-risk patients with pancreatic neoplasms that warrant resection. Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) offers a minimally invasive and potentially...

(This article belongs to the Special Issue Diagnosis and Management of Pancreatic Cysts)
  • Review
  • Open Access
16 Citations
4,130 Views
10 Pages

In this paper, authors introduce the basic prerequisite for rational, targeted, and above all, child-oriented diagnosis of fractures and dislocations in children and adolescents is in-depth prior knowledge of the special features of trauma in the gro...

(This article belongs to the Special Issue Diagnosis and Management in Trauma Surgery)
  • Review
  • Open Access
21 Citations
5,896 Views
15 Pages

Optic Nerve Ultrasound Evaluation in Children: A Review

  • Giulia Abbinante,
  • Livio Vitiello,
  • Alessia Coppola,
  • Giulio Salerno,
  • Vincenzo Gagliardi and
  • Alfonso Pellegrino

Managing patients with neurocritical illness requires monitoring and treating elevated intracranial pressure (ICP), especially in cases in children. In terms of precise and real-time measurements, invasive ICP measurements are presently the gold stan...

(This article belongs to the Special Issue Editorial Board Members’ Collection Series—Advances in Ultrasound)
  • Article
  • Open Access
81 Citations
9,082 Views
16 Pages

Performance Analysis of Deep Learning Algorithms in Diagnosis of Malaria Disease

  • K. Hemachandran,
  • Areej Alasiry,
  • Mehrez Marzougui,
  • Shahid Mohammad Ganie,
  • Anil Audumbar Pise,
  • M. Turki-Hadj Alouane and
  • Channabasava Chola

Malaria is predominant in many subtropical nations with little health-monitoring infrastructure. To forecast malaria and condense the disease’s impact on the population, time series prediction models are necessary. The conventional technique of...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Systematic Review
  • Open Access
11 Citations
3,958 Views
19 Pages

Artificial intelligence (AI) has been steadily developing in the medical field in the past few years, and AI-based applications have advanced cancer diagnosis. Breast cancer has a massive amount of data in oncology. There has been a high level of res...

(This article belongs to the Special Issue AI and Medical Imaging in Breast Disease)
  • Article
  • Open Access
10 Citations
2,766 Views
11 Pages

Diagnostic Value of DECT-Based Collagen Mapping for Assessing the Distal Tibiofibular Syndesmosis in Patients with Acute Trauma

  • Leon David Gruenewald,
  • Daniel H. Leitner,
  • Vitali Koch,
  • Simon S. Martin,
  • Ibrahim Yel,
  • Scherwin Mahmoudi,
  • Simon Bernatz,
  • Katrin Eichler,
  • Tatjana Gruber-Rouh and
  • Christian Booz
  • + 3 authors

Background: Injury to the distal tibiofibular syndesmosis (DTFS) is common in patients with trauma to the ankle, but diagnostic accuracy of conventional X-ray and CT is insufficient. A novel dual energy CT (DECT) post-processing algorithm enables col...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
19 Citations
6,173 Views
18 Pages

Evaluation of Blood Biomarkers and Parameters for the Prediction of Stroke Survivors’ Functional Outcome upon Discharge Utilizing Explainable Machine Learning

  • Aimilios Gkantzios,
  • Christos Kokkotis,
  • Dimitrios Tsiptsios,
  • Serafeim Moustakidis,
  • Elena Gkartzonika,
  • Theodoros Avramidis,
  • Nikolaos Aggelousis and
  • Konstantinos Vadikolias

Despite therapeutic advancements, stroke remains a leading cause of death and long-term disability. The quality of current stroke prognostic models varies considerably, whereas prediction models of post-stroke disability and mortality are restricted...

(This article belongs to the Special Issue Medical Diagnostic Systems Based on Advancing Artificial Intelligence Concepts)
  • Article
  • Open Access
7 Citations
5,109 Views
16 Pages

Misdiagnosis of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) can occur when different case definitions are used by clinicians (relative misdiagnosis) or when failing the genuine diagnosis of another disease (misdiagnosis in a strict se...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
6 Citations
2,470 Views
11 Pages

Effects of Acidic Challenge on Demineralized Root Surface Treated with Silver Diamine Fluoride and Potassium Iodide

  • Alexandru Iovan,
  • Marcelin Benchea,
  • Simona Stoleriu,
  • Ionuț Tărăboanță,
  • Nicanor Cimpoeșu,
  • Irina Nica and
  • Sorin Andrian

Background: The aim of the study was to assess the protective effect of applying potassium iodide (KI) over silver diamine fluoride (SDF) on demineralized root dentin in the case of a sustained acidogenic attack. Methods: Forty caries-free third mola...

(This article belongs to the Special Issue Diagnosis and Treatment of Periodontal Diseases in 2022)
  • Article
  • Open Access
4 Citations
7,680 Views
11 Pages

Comparing Outcomes of Single-Incision Laparoscopic Herniorrhaphy in Newborns and Infants

  • Tsung-Jung Tsai,
  • Ching-Min Lin,
  • I Nok Cheang,
  • Yao-Jen Hsu,
  • Chin-Hun Wei,
  • Tai-Wai Chin,
  • Chin-Yen Wu,
  • Wen-Yuan Chang and
  • Yu-Wei Fu

Background: As surgical techniques progress, laparoscopic herniorrhaphy is now performed more often in premature babies. The aim of this study was to analyze the outcomes of newborns and infants who underwent single-incision laparoscopic herniorrhaph...

(This article belongs to the Section Biomedical Optics)
  • Article
  • Open Access
1 Citations
3,130 Views
12 Pages

High Plasma Levels of Neopterin Are Associated with Increased Mortality among Children with Severe Malaria in Benin

  • Samuel Odarkwei Blankson,
  • Lauriane Rietmeyer,
  • Patrick Tettey,
  • Liliane Dikroh,
  • Bernard Tornyigah,
  • Rafiou Adamou,
  • Azizath Moussiliou,
  • Caroline Padounou,
  • Annick Amoussou and
  • Rachida Tahar
  • + 5 authors

Among the barriers to accessing adequate treatment and high-level monitoring for malaria febrile patients is the lack of effective prognostic markers. Neopterin, which is a marker of monocyte/macrophage activation, was found have increased during sev...

(This article belongs to the Special Issue Diagnosis and Management of Malaria)

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Diagnostics - ISSN 2075-4418