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Life, Volume 12, Issue 7

July 2022 - 178 articles

Cover Story: Cardiotoxicity is the most concerning cardiovascular complication in cancer patients, caused mainly by anticancer drugs. The harmful mechanism includes DNA damage, endothelial dysfunction. and oxidative stress. In cancer patients, exercise is safe, well tolerated, associated with improved fitness, and can mitigate the adverse effects of anticancer therapy. Cardiac rehabilitation has a potential to mitigate cardiotoxicity based on the benefits on populations with cancer or with heart diseases, and as the cardiotoxic harm mechanisms coincide with similar mechanisms positively affected by cardiac rehabilitation. As the digital era is here and as these patients require specially tailored programs, a remote, home-based cardio-oncology rehabilitation program may be a solution for this population. View this paper
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Articles (178)

  • Article
  • Open Access
5 Citations
2,237 Views
8 Pages

21 July 2022

Synchronization between heart rate variability (HRV) in the low-frequency (LF) range (0.04–0.15 Hz) and 1-min variations in the components (X, Y, Z)and the total vector (F) of geomagnetic induction (nT) was studied in normotensive (blood pressu...

  • Article
  • Open Access
2 Citations
2,527 Views
15 Pages

Heritability Estimation of Multiple Sclerosis Related Plasma Protein Levels in Sardinian Families with Immunochip Genotyping Data

  • Andrea Nova,
  • Giulia Nicole Baldrighi,
  • Teresa Fazia,
  • Francesca Graziano,
  • Valeria Saddi,
  • Marialuisa Piras,
  • Ashley Beecham,
  • Jacob L. McCauley and
  • Luisa Bernardinelli

21 July 2022

This work aimed at estimating narrow-sense heritability, defined as the proportion of the phenotypic variance explained by the sum of additive genetic effects, via Haseman–Elston regression for a subset of 56 plasma protein levels related to Mu...

  • Article
  • Open Access
27 Citations
4,620 Views
18 Pages

21 July 2022

Dementia is a neurological condition that primarily affects older adults and there is still no cure or therapy available to cure it. The symptoms of dementia can appear as early as 10 years before the beginning of actual diagnosed dementia. Hence, ma...

  • Article
  • Open Access
13 Citations
3,210 Views
10 Pages

21 July 2022

Healthcare systems have been under immense pressure since the beginning of the COVID-19 pandemic; hence, studies on using machine learning (ML) methods for classifying ICU admissions and resource allocation are urgently needed. We investigated whethe...

  • Case Report
  • Open Access
7 Citations
2,269 Views
4 Pages

Clinical and Virological Response to Convalescent Plasma in a Chronic Lymphocytic Leukemia Patient with COVID-19 Pneumonia

  • Giovanni Belcari,
  • Alberto Conti,
  • Alessandro Mazzoni,
  • Maria Lanza,
  • Paola Mazzetti and
  • Daniele Focosi

21 July 2022

The burden of COVID-19 remains unchanged for immunocompromised patients who do not respond to vaccines. Unfortunately, Omicron sublineages are resistant to monoclonal antibodies authorized in Europe so far, and small chemical antivirals have contrain...

  • Article
  • Open Access
11 Citations
3,106 Views
24 Pages

Novel Nanoconjugate of Apamin and Ceftriaxone for Management of Diabetic Wounds

  • Abdullah A. Alamoudi,
  • Awaad S. Alharbi,
  • Ashraf B. Abdel-Naim,
  • Shaimaa M. Badr-Eldin,
  • Zuhier A. Awan,
  • Solomon Z. Okbazghi,
  • Osama A. A. Ahmed,
  • Nabil A. Alhakamy,
  • Usama A. Fahmy and
  • Ahmed Esmat

21 July 2022

Diabetic hyperglycemia delays wound healing, leading to serious consequences. Topical antibiotics can reduce the risk of a wound infection during healing; nevertheless, the microbial fight against antibiotics brings about public health challenges. An...

  • Communication
  • Open Access
4 Citations
2,606 Views
10 Pages

21 July 2022

Plant leaves, which convert light energy into chemical energy, serve as a major food source on Earth. The decrease in crop yield and quality is caused by plant leaf premature senescence. It is important to detect senescence-associated genes. In this...

  • Article
  • Open Access
5 Citations
3,158 Views
12 Pages

Alzheimer’s Disease Risk Variant rs3865444 in the CD33 Gene: A Possible Role in Susceptibility to Multiple Sclerosis

  • Juraj Javor,
  • Mária Bucová,
  • Vladimíra Ďurmanová,
  • Dominika Radošinská,
  • Zuzana Párnická,
  • Daniel Čierny,
  • Egon Kurča,
  • Daniela Čopíková-Cudráková,
  • Karin Gmitterová and
  • Ivana Shawkatová

21 July 2022

Polymorphisms in genes encoding receptors that modulate the activity of microglia and macrophages are attractive candidates for participation in genetic susceptibility to multiple sclerosis (MS). The aims of the study were to (1) investigate the asso...

  • Article
  • Open Access
25 Citations
6,425 Views
15 Pages

Fatty Acid Composition of Milk from Mothers with Normal Weight, Obesity, or Gestational Diabetes

  • Livia Simon Sarkadi,
  • Miaomiao Zhang,
  • Géza Muránszky,
  • Réka Anna Vass,
  • Oksana Matsyura,
  • Eszter Benes and
  • Sandor G. Vari

21 July 2022

Gestation and the neonatal period are crucial periods in infant development. Many components of breast milk, including fatty acids, play an important role in strengthening the immune system. The aim of our research was to evaluate the fatty acid prof...

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Life - ISSN 2075-1729