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Genes, Volume 11, Issue 10

October 2020 - 124 articles

Cover Story: Adaptation to changing environment is a growing challenge in the era of the “Anthropocene”, and populations capable of rapid adaptation to novel selection pressures are more likely to survive. The Caspian whipsnake (Dolichophis caspius) is a large-bodied, non-venomous colubrid and inhabits dry steppe and Mediterranean habitats, from Eastern Europe around the Caspian and Black Sea to the north-western edge of its distribution in Hungary. Applying ddRAD sequencing we investigated genetic diversity and adaptive evolution to local habitat types and identified 751 selected genotypes correlated with seven key climatic variables. We found that isothermality may have an important role in the distribution and adaptation of Caspian whipsnakes. View this paper
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Articles (124)

  • Article
  • Open Access
15 Citations
7,878 Views
18 Pages

GJB2 and GJB6 Genetic Variant Curation in an Argentinean Non-Syndromic Hearing-Impaired Cohort

  • Paula Buonfiglio,
  • Carlos D. Bruque,
  • Leonela Luce,
  • Florencia Giliberto,
  • Vanesa Lotersztein,
  • Sebastián Menazzi,
  • Bibiana Paoli,
  • Ana Belén Elgoyhen and
  • Viviana Dalamón

21 October 2020

Genetic variants in GJB2 and GJB6 genes are the most frequent causes of hereditary hearing loss among several deaf populations worldwide. Molecular diagnosis enables proper genetic counseling and medical prognosis to patients. In this study, we prese...

  • Article
  • Open Access
22 Citations
5,456 Views
20 Pages

21 October 2020

The genus Lactobacillus includes species that may inhabit different anatomical locations in the human body, but the greatest percentage of its species are inhabitants of the gut. Lactobacilli are well known for their probiotic characteristics, althou...

  • Article
  • Open Access
2 Citations
3,644 Views
20 Pages

Identification of Novel Interspersed DNA Repetitive Elements in the Trypanosoma cruzi Genome Associated with the 3′UTRs of Surface Multigenic Families

  • Simone Guedes Calderano,
  • Milton Yutaka Nishiyama Junior,
  • Marjorie Marini,
  • Nathan de Oliveira Nunes,
  • Marcelo da Silva Reis,
  • José Salvatore Leister Patané,
  • José Franco da Silveira,
  • Julia Pinheiro Chagas da Cunha and
  • Maria Carolina Elias

21 October 2020

Trypanosoma cruzi is the etiological agent of Chagas disease, which affects millions of people in Latin America. No transcriptional control of gene expression has been demonstrated in this organism, and 50% of its genome consists of repetitive elemen...

  • Article
  • Open Access
4 Citations
3,422 Views
17 Pages

20 October 2020

Ceriporiopsis subvermispora is a white-rot fungus with a high specificity towards lignin mineralization when colonizing dead wood or lignocellulosic compounds. Its lignocellulose degrading system is formed by cellulose hydrolytic enzymes, manganese p...

  • Article
  • Open Access
24 Citations
4,060 Views
39 Pages

20 October 2020

In China, the production for duck meat is second only to that of chicken, and the demand for duck meat is also increasing. However, there is still unclear on the internal mechanism of regulating skeletal muscle growth and development in duck. This st...

  • Article
  • Open Access
11 Citations
3,846 Views
25 Pages

Genome-Wide Transcriptome Profiling Provides Insight on Cholesterol and Lithocholate Degradation Mechanisms in Nocardioides simplex VKM Ac-2033D

  • Victoria Y. Shtratnikova,
  • Mikhail I. Schelkunov,
  • Victoria V. Fokina,
  • Eugeny Y. Bragin,
  • Tatyana G. Lobastova,
  • Andrey A. Shutov,
  • Alexey V. Kazantsev and
  • Marina V. Donova

20 October 2020

Steroid microbial degradation plays a significant ecological role for biomass decomposition and removal/detoxification of steroid pollutants. In this study, the initial steps of cholesterol degradation and lithocholate bioconversion by a strain with...

  • Article
  • Open Access
10 Citations
3,728 Views
17 Pages

bta-miR-23a Regulates the Myogenic Differentiation of Fetal Bovine Skeletal Muscle-Derived Progenitor Cells by Targeting MDFIC Gene

  • Xin Hu,
  • Yishen Xing,
  • Ling Ren,
  • Yahui Wang,
  • Qian Li,
  • Qiyuan Yang,
  • Min Du,
  • Lingyang Xu,
  • Luc Willems and
  • Junya Li
  • + 1 author

20 October 2020

miR-23a, a member of the miR-23a/24-2/27a cluster, has been demonstrated to play pivotal roles in many cellular activities. However, the mechanisms of how bta-miR-23a controls the myogenic differentiation (MD) of PDGFRα− bovine progenitor...

  • Article
  • Open Access
1 Citations
6,450 Views
13 Pages

Genome-Wide Co-Expression Distributions as a Metric to Prioritize Genes of Functional Importance

  • Pâmela A. Alexandre,
  • Nicholas J. Hudson,
  • Sigrid A. Lehnert,
  • Marina R. S. Fortes,
  • Marina Naval-Sánchez,
  • Loan T. Nguyen,
  • Laercio R. Porto-Neto and
  • Antonio Reverter

20 October 2020

Genome-wide gene expression analysis are routinely used to gain a systems-level understanding of complex processes, including network connectivity. Network connectivity tends to be built on a small subset of extremely high co-expression signals that...

  • Article
  • Open Access
4 Citations
4,291 Views
19 Pages

19 October 2020

Domestication of a new crop requires identification and improvement of desirable characteristics Field cress (Lepidium campestre) is being domesticated as a new oilseed crop, particularly for northern temperate regions.. In the present study, an F2 m...

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Genes - ISSN 2073-4425