Polymers, Volume 10, Issue 6 (June 2018) – 126 articles
Cover Story (view full-size image): Dendritic polyglycerol sulfate (dPGS) is a polyanionic polymer originally investigated as a substitute for heparin. As dPGS showed much less anticoagulant activity, but high anti-inflammatory activity and the ability to target inflamed tissue, it has since been examined for the treatment of inflammatory conditions and related diseases, including rheumatoid and osteoarthritis as well as neurological disorders. Additionally, it showed promising results as a carrier for anticancer drugs, as well as for the treatment of virus infections. Radio- and dye-labeled analogs were used to track dPGS. Our review summarizes the potential applications of dPGS for the imaging, diagnosis and treatment of different diseases. View this paper.
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