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  • Hematology Reports is published by MDPI from Volume 14 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.

Hematology Reports, Volume 13, Issue 4

November 2021 - 4 articles

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Articles (4)

  • Article
  • Open Access
8 Citations
1,705 Views
5 Pages
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Impact of Pharmacokinetics to Reduce Bleeding in a Cohort of Patients with Severe Hemophilia A in a Personalized Comprehensive Management Program

  • Samuel Sarmiento Doncel,
  • Gina Alejandra Diaz Mosquera,
  • Javier Mauricio Cortes,
  • Nelson Ramirez Plazas,
  • Francisco Javier Meza and
  • Carol Agudelo Rico
Hematol. Rep.2021, 13(4), 8904;https://doi.org/10.4081/hr.2021.8904

26 November 2021

In recent decades, hemophilia A treatment has been focused on body weight, without taking pharmacokinetic parameters into account. Previous research has shown that the individual pharmacokinetic response is more effective in predicting the required d...

Full Article
  • Case Report
  • Open Access
2 Citations
1,396 Views
2 Pages
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Therapeutic Innovation for Multi-Resistant Candidemics: Synergy of Isavuconazole and Caspofungin Association

  • Andrea Duminuco,
  • Elisa Mauro,
  • Giuseppe A. M. Palumbo,
  • Bruno Garibaldi,
  • Marina Parisi,
  • Francesco Di Raimondo,
  • Cinzia Maugeri and
  • Calogero Vetro
Hematol. Rep.2021, 13(4), 9329;https://doi.org/10.4081/hr.2021.9329

26 November 2021

Fungal infections occurring in immunocompromised patients after immuno-chemotherapy treatment, are often difficult to eradicate and capable of even being fatal. Systemic mycoses affecting severely immunocompromised patients often manifest acutely wit...

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  • Article
  • Open Access
4 Citations
1,630 Views
5 Pages
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Lysine-Specific Histone Demethylase 1 Inhibition Enhances Robust Fetal Hemoglobin Induction in Human β0-Thalassemia/Hemoglobin E Rrythroid Cells

  • Woratree Kaewsakulthong,
  • Phitchapa Pongpaksupasin,
  • Tiwaporn Nualkaew,
  • Suradej Hongeng,
  • Suthat Fucharoen,
  • Natee Jearawiriyapaisarn and
  • Orapan Sripichai
Hematol. Rep.2021, 13(4), 9215;https://doi.org/10.4081/hr.2021.9215

26 November 2021

Induction of fetal hemoglobin (HbF) ameliorates the clinical severity of β-thalassemias. Histone methyltransferase LSD1 enzyme removes methyl groups from the activating chromatin mark histone 3 lysine 4 at silenced genes, including the γ-globin genes...

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  • Review
  • Open Access
5 Citations
1,626 Views
6 Pages
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Direct Oral Anticoagulants: A Review for the Non-Specialist

  • Thilina Gunawardena
Hematol. Rep.2021, 13(4), 9239;https://doi.org/10.4081/hr.2021.9239

26 November 2021

Thrombin inhibitors and direct factor Xa inhibitors represent a major breakthrough in the field of anticoagulation pharmacotherapy. These novel agents have replaced warfarin as the oral anticoagulant of choice in certain indications, as they possess...

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