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Viruses, Volume 9, Issue 10

October 2017 - 47 articles

Cover Story: Viruses use silencing suppressor proteins to combat or avoid a plant’s intrinsic RNA silencing defense mechanism. In the family Luteoviridae, members of the genera Polerovirus and Enamovirus have a strong suppressor of local and systemic RNA silencing, named P0. Members of the genus Luteovirus, however, lack the corresponding ORF 0. We show that, in the absence of P0, luteoviruses have evolved a P4 movement protein that also displays strong systemic silencing suppression activity by inhibiting the accumulation of small RNAs. View this paper
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Articles (47)

  • Article
  • Open Access
10 Citations
5,321 Views
12 Pages

16 October 2017

Bivalent vaccines based on live attenuated viruses expressing a heterologous protein are an attractive strategy to address co-infections with various pathogens in the field. Considering the excellent efficacy and safety of the lapinized live attenuat...

  • Article
  • Open Access
12 Citations
6,016 Views
15 Pages

Random Network Models to Predict the Long-Term Impact of HPV Vaccination on Genital Warts

  • Javier Díez-Domingo,
  • Víctor Sánchez-Alonso,
  • Rafael-J. Villanueva,
  • Luis Acedo,
  • José-Antonio Moraño and
  • Javier Villanueva-Oller

16 October 2017

The Human papillomaviruses (HPV) vaccine induces a herd immunity effect in genital warts when a large number of the population is vaccinated. This aspect should be taken into account when devising new vaccine strategies, like vaccination at older age...

  • Article
  • Open Access
24 Citations
8,706 Views
12 Pages

Seed Transmission of Beet Curly Top Virus and Beet Curly Top Iran Virus in a Local Cultivar of Petunia in Iran

  • Ameneh Anabestani,
  • Seyed Ali Akbar Behjatnia,
  • Keramat Izadpanah,
  • Saeid Tabein and
  • Gian Paolo Accotto

16 October 2017

Beet curly top virus (BCTV) and beet curly top Iran virus (BCTIV) are known as the causal agents of curly top disease in beet and several other dicotyledonous plants in Iran. These viruses are transmitted by Circulifer species, and until now, there h...

  • Article
  • Open Access
61 Citations
7,814 Views
18 Pages

MicroRNA and mRNA Dysregulation in Astrocytes Infected with Zika Virus

  • Robert A. Kozak,
  • Anna Majer,
  • Mia J. Biondi,
  • Sarah J. Medina,
  • Lee W. Goneau,
  • Babu V. Sajesh,
  • Jessy A. Slota,
  • Vanessa Zubach,
  • Alberto Severini and
  • David Safronetz
  • + 5 authors

14 October 2017

The Zika virus (ZIKV) epidemic is an ongoing public health concern. ZIKV is a flavivirus reported to be associated with microcephaly, and recent work in animal models demonstrates the ability of the virus to cross the placenta and affect fetal brain...

  • Article
  • Open Access
7 Citations
5,828 Views
11 Pages

A Next-Generation Sequencing Approach Uncovers Viral Transcripts Incorporated in Poxvirus Virions

  • Marica Grossegesse,
  • Joerg Doellinger,
  • Berit Haldemann,
  • Lars Schaade and
  • Andreas Nitsche

13 October 2017

Transcripts are known to be incorporated in particles of DNA viruses belonging to the families of Herpesviridae and Mimiviridae, but the presence of transcripts in other DNA viruses, such as poxviruses, has not been analyzed yet. Therefore, we first...

  • Article
  • Open Access
10 Citations
5,758 Views
9 Pages

The Evolutionary History and Spatiotemporal Dynamics of the NC Lineage of Citrus Tristeza Virus

  • María José Benítez-Galeano,
  • Matías Castells and
  • Rodney Colina

12 October 2017

Citrus tristeza virus (CTV) is a major pathogen affecting citrus trees worldwide. However, few studies have focused on CTV’s evolutionary history and geographic behavior. CTV is locally dispersed by an aphid vector and long distance dispersion due to...

  • Article
  • Open Access
15 Citations
6,896 Views
15 Pages

Expression Profiles of Ligands for Activating Natural Killer Cell Receptors on HIV Infected and Uninfected CD4+ T Cells

  • Alexandra Tremblay-McLean,
  • Julie Bruneau,
  • Bertrand Lebouché,
  • Irene Lisovsky,
  • Rujun Song and
  • Nicole F. Bernard

12 October 2017

Natural Killer (NK) cell responses to HIV-infected CD4 T cells (iCD4) depend on the integration of signals received through inhibitory (iNKR) and activating NK receptors (aNKR). iCD4 activate NK cells to inhibit HIV replication. HIV infection-depende...

  • Review
  • Open Access
53 Citations
12,154 Views
18 Pages

Why Human Papillomavirus Acute Infections Matter

  • Samuel Alizon,
  • Carmen Lía Murall and
  • Ignacio G. Bravo

10 October 2017

Most infections by human papillomaviruses (HPVs) are `acute’, that is non-persistent. Yet, for HPVs, as for many other oncoviruses, there is a striking gap between our detailed understanding of chronic infections and our limited data on the early sta...

  • Article
  • Open Access
30 Citations
8,101 Views
16 Pages

The Luteovirus P4 Movement Protein Is a Suppressor of Systemic RNA Silencing

  • Adriana F. Fusaro,
  • Deborah A. Barton,
  • Kenlee Nakasugi,
  • Craig Jackson,
  • Melanie L. Kalischuk,
  • Lawrence M. Kawchuk,
  • Maite F. S. Vaslin,
  • Regis L. Correa and
  • Peter M. Waterhouse

10 October 2017

The plant viral family Luteoviridae is divided into three genera: Luteovirus, Polerovirus and Enamovirus. Without assistance from another virus, members of the family are confined to the cells of the host plant’s vascular system. The first open readi...

  • Review
  • Open Access
93 Citations
11,112 Views
19 Pages

Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins

  • Shun Chen,
  • Zhen Wu,
  • Mingshu Wang and
  • Anchun Cheng

7 October 2017

Flaviviridae-caused diseases are a critical, emerging public health problem worldwide. Flaviviridae infections usually cause severe, acute or chronic diseases, such as liver damage and liver cancer resulting from a hepatitis C virus (HCV) infection a...

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Viruses - ISSN 1999-4915