You are currently viewing a new version of our website. To view the old version click .

Viruses, Volume 17, Issue 4

April 2025 - 136 articles

Cover Story: Persistent infection with HPV causes nearly 5% of all cancers worldwide, including cervical and oropharyngeal cancers. Compared to HPV− head and neck squamous-cell carcinomas (HNSCCs), HPV+ HNSCCs exhibit a significantly improved treatment response; however, the established treatment regimens were largely developed for HPV− disease. Effectively de-escalating therapy and optimizing treatment protocols to minimize toxicity for both HPV+ and HPV− tumors has seen varying success, in part due to the heterogeneity of cellular subpopulations. To address this by means of an exploration of the underlying biology, we analyzed published single-cell RNA sequencing data of HPV+ and HPV− HNSCCs to distinguish epithelial tumor cell populations as a function of HPV status. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (136)

  • Article
  • Open Access
2,000 Views
16 Pages

Genetic Profiles of Ten African Swine Fever Virus Strains from Outbreaks in Select Provinces of Luzon, Visayas, and Mindanao, Philippines, Between 2021 and 2023

  • Andrew D. Montecillo,
  • Zyne K. Baybay,
  • Jimwel Bryan Christopher Ferrer,
  • Wreahlen Cariaso,
  • Airish Pantua,
  • John Paulo Jose,
  • Rachel Madera,
  • Jishu Shi,
  • Karla Cristine Doysabas and
  • Alan Dargantes
  • + 5 authors

21 April 2025

An African Swine Fever (ASF) outbreak was first recorded in the Philippines in July 2019. Since then, the disease has spread across provinces in Luzon, Visayas, and Mindanao, causing severe economic consequences for the country’s swine industry...

  • Review
  • Open Access
1 Citations
996 Views
16 Pages

19 April 2025

Orf virus (ORFV) is the type species of Parapoxvirus of the Poxviridae family that induces cutaneous pustular skin lesions in sheep and goats, and causes zoonotic infections in humans. Pattern recognition receptors (PRRs) sense pathogen-associated mo...

  • Article
  • Open Access
1 Citations
1,127 Views
19 Pages

Pathogen Profile of Children Hospitalised with Viral Respiratory Infections in Galati County, Romania

  • Elena-Roxana Matache (Vasilache),
  • Gabriela Gurau,
  • Cosmin-Raducu Raileanu,
  • Anamaria Zaharescu,
  • Gabriel Valeriu Popa,
  • Nicoleta-Maricica Maftei,
  • Camelia Busila,
  • Madalina Nicoleta Matei and
  • Dana Tutunaru

19 April 2025

Respiratory infections are the most common infectious diseases among children, representing a cause of death and generating a significant number of hospitalisations. The aim of the study was to analyse the epidemiological and clinical characteristics...

  • Article
  • Open Access
1 Citations
1,206 Views
15 Pages

Short-Read and Long-Read Whole Genome Sequencing for SARS-CoV-2 Variants Identification

  • Mengfei Peng,
  • Morgan L. Davis,
  • Meghan L. Bentz,
  • Alex Burgin,
  • Mark Burroughs,
  • Jasmine Padilla,
  • Sarah Nobles,
  • Yvette Unoarumhi and
  • Kevin Tang

18 April 2025

Genomic surveillance of SARS-CoV-2 is crucial for detecting emerging variants and informing public health responses. Various sequencing technologies are used for whole genome sequencing of SARS-CoV-2. This cross-platform benchmark study applied estab...

  • Article
  • Open Access
1 Citations
1,430 Views
13 Pages

Detection of Avian Influenza Virus in Pigeons

  • Ning Cui,
  • Peipei Wang,
  • Qinghua Huang,
  • Zihao Yuan,
  • Shuai Su,
  • Chuantian Xu and
  • Lihong Qi

18 April 2025

Pigeons (Columba livia) are usually kept as free-ranging or racing birds, and they have direct contact with livestock, poultry, and humans. Therefore, they may have an important role in the ecology of influenza virus among various species. In the pre...

  • Article
  • Open Access
680 Views
15 Pages

18 April 2025

Human Immunodeficiency Virus (HIV) Type-1 has been studied heavily for decades, yet one area that is still poorly understood is the virus’ ability to cause cell–cell fusion. In HIV, the fusion process is mediated by viral surface glycopro...

  • Article
  • Open Access
996 Views
13 Pages

Complete Genome Sequencing of the Divergent Guiana Dolphin Morbillivirus (GDMV), Brazil

  • Kátia Regina Groch,
  • Sueli Akemi Taniwaki Miyagi,
  • Josué Díaz-Delgado,
  • Elitieri B. Santos-Neto,
  • José Lailson-Brito,
  • Paulo Eduardo Brandão and
  • José Luiz Catão-Dias

18 April 2025

Cetacean morbillivirus (CeMV) is a major threat to cetaceans worldwide, causing individual deaths and outbreaks of mass mortality. Based on partial sequences of the viral phosphoprotein, CeMV is subclassified into seven strains and two distinct linea...

  • Review
  • Open Access
2 Citations
1,681 Views
20 Pages

Advances in the Drug Development and Quality Evaluation Principles of Oncolytic Herpes Simplex Virus

  • Basma Eid Abdullah Ghorab,
  • Tongtan Liu,
  • Min Ying,
  • Ping Wang,
  • Meirong Qin,
  • Jiayong Xing,
  • Huadong Wang and
  • Fuqiang Xu

18 April 2025

Oncolytic herpes simplex virus (oHSV) represents a promising therapeutic approach to treating cancers by virtue of its selective replication in and lysis of tumor cells, with stimulation of host antitumor immunity. At present, four OV drugs have been...

  • Article
  • Open Access
916 Views
23 Pages

17 April 2025

Pseudorabies virus (PRV) is a pathogen that causes severe neurological dysfunction in the host, leading to extensive neuronal damage and inflammation. Despite extensive research on the neuropathogenesis of α-herpesvirus infections, many scienti...

  • Article
  • Open Access
1 Citations
979 Views
19 Pages

17 April 2025

Virus-like particles are a well-established platform for vaccines, although the molecular mechanisms that underlie the extraordinary potency of many virus-like particles in eliciting strong antibody responses remain incompletely understood. Here, we...

of 14

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Viruses - ISSN 1999-4915Creative Common CC BY license