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Viruses, Volume 11, Issue 12

December 2019 - 85 articles

Cover Story: To investigate the role of viral capsid residues in transmission by a plant-feeding nematode, we need mutants able to infect plants systemically. We report on our progression from a grapevine fanleaf virus mutant impaired in encapsidation and movement to the identification of a new transmission determinant composed of region R4 and Arg301 of the coat protein. It lies in close proximity to a charged cavity, likely constituting the binding pocket (LBP) of the virus in the nematode’s mouthpart.View this paper.
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Articles (85)

  • Review
  • Open Access
21 Citations
6,055 Views
27 Pages

17 December 2019

The Alphaherpesvirinae include the neurotropic pathogens herpes simplex virus and varicella zoster virus of humans and pseudorabies virus of swine. These viruses establish lifelong latency in the nuclei of peripheral ganglia, but utilize the peripher...

  • Article
  • Open Access
16 Citations
3,825 Views
17 Pages

Homburgvirus LP-018 Has a Unique Ability to Infect Phage-Resistant Listeria monocytogenes

  • Yaxiong Song,
  • Tracey L. Peters,
  • Daniel W. Bryan,
  • Lauren K. Hudson and
  • Thomas G. Denes

17 December 2019

Listeria phage LP-018 is the only phage from a diverse collection of 120 phages able to form plaques on a phage-resistant Listeria monocytogenes strain lacking rhamnose in its cell wall teichoic acids. The aim of this study was to characterize phage...

  • Article
  • Open Access
31 Citations
3,973 Views
14 Pages

IFI16 Inhibits Porcine Reproductive and Respiratory Syndrome Virus 2 Replication in a MAVS-Dependent Manner in MARC-145 Cells

  • Xiaobo Chang,
  • Xibao Shi,
  • Xiaozhuan Zhang,
  • Li Wang,
  • Xuewu Li,
  • Aiping Wang,
  • Ruiguang Deng,
  • Enmin Zhou and
  • Gaiping Zhang

16 December 2019

Porcine reproductive and respiratory syndrome virus (PRRSV) is a single-stranded positive-sense RNA virus, and the current strategies for controlling PRRSV are limited. Interferon gamma-inducible protein 16 (IFI16) has been reported to have a broader...

  • Review
  • Open Access
9 Citations
4,726 Views
16 Pages

16 December 2019

Viral lymphomagenesis induced by infection with oncogenic viruses, such as Kaposi’s sarcoma associated herpesvirus (KSHV), Epstein–Barr virus (EBV) and human T-cell leukemia virus (HTLV-1), represents a group of aggressive malignancies wi...

  • Brief Report
  • Open Access
12 Citations
3,438 Views
14 Pages

16 December 2019

No effective therapy to eliminate the HIV latently infected cell reservoir has been developed. One approach, “shock and kill”, employs agents that activate HIV, subsequently killing the activated infected cells and/or virus. Shock and kil...

  • Article
  • Open Access
13 Citations
4,471 Views
20 Pages

Genomic and Proteomic Characterization of Bacteriophage BH1 Spontaneously Released from Probiotic Lactobacillus rhamnosus Pen

  • Piotr Jarocki,
  • Elwira Komoń-Janczara,
  • Marcin Podleśny,
  • Oleksandr Kholiavskyi,
  • Monika Pytka and
  • Monika Kordowska-Wiater

16 December 2019

Lactobacillus rhamnosus Pen is a human endogenous strain used for the production of probiotic formula, which is effective in the prevention of antibiotic-associated diarrhoea. Our study showed that this probiotic strain releases bacteriophage BH1 wit...

  • Article
  • Open Access
19 Citations
8,408 Views
18 Pages

Zika Virus Surveillance at the Human–Animal Interface in West-Central Brazil, 2017–2018

  • Alex Pauvolid-Corrêa,
  • Helver Gonçalves Dias,
  • Laura Marina Siqueira Maia,
  • Grasiela Porfírio,
  • Thais Oliveira Morgado,
  • Gilberto Sabino-Santos,
  • Paula Helena Santa Rita,
  • Wanessa Teixeira Gomes Barreto,
  • Gabriel Carvalho de Macedo and
  • Jaire Marinho Torres
  • + 61 authors

16 December 2019

Zika virus (ZIKV) was first discovered in 1947 in Uganda but was not considered a public health threat until 2007 when it found to be the source of epidemic activity in Asia. Epidemic activity spread to Brazil in 2014 and continued to spread througho...

  • Article
  • Open Access
23 Citations
6,371 Views
24 Pages

14 December 2019

Host proteins that are central to infection of potyviruses (genus Potyvirus; family Potyviridae) include the eukaryotic translation initiation factors eIF4E and eIF(iso)4E. The potyviral genome-linked protein (VPg) and the helper component proteinase...

  • Article
  • Open Access
20 Citations
7,240 Views
18 Pages

Ecology of West Nile Virus in the Danube Delta, Romania: Phylogeography, Xenosurveillance and Mosquito Host-Feeding Patterns

  • Alexandru Tomazatos,
  • Stephanie Jansen,
  • Stefan Pfister,
  • Edina Török,
  • Iulia Maranda,
  • Cintia Horváth,
  • Lujza Keresztes,
  • Marina Spînu,
  • Egbert Tannich and
  • Hanna Jöst
  • + 3 authors

14 December 2019

The ecology of West Nile virus (WNV) in the Danube Delta Biosphere Reserve (Romania) was investigated by combining studies on the virus genetics, phylogeography, xenosurveillance and host-feeding patterns of mosquitoes. Between 2014 and 2016, 655,667...

  • Article
  • Open Access
24 Citations
5,839 Views
25 Pages

Modelling Vector Transmission and Epidemiology of Co-Infecting Plant Viruses

  • Linda J. S. Allen,
  • Vrushali A. Bokil,
  • Nik J. Cunniffe,
  • Frédéric M. Hamelin,
  • Frank M. Hilker and
  • Michael J. Jeger

13 December 2019

Co-infection of plant hosts by two or more viruses is common in agricultural crops and natural plant communities. A variety of models have been used to investigate the dynamics of co-infection which track only the disease status of infected and co-in...

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Viruses - ISSN 1999-4915