- Editorial
7 Citations
2,533 Views
5 Pages
Breast cancer (BC) is the most prevalent form of cancer among women worldwide, accounting for over 2 million diagnoses annually [...]
- 3.4Impact Factor
- 4.9CiteScore
- 22 daysTime to First Decision
Current Oncology, Volume 31, Issue 1
January 2024 - 43 articles
Cover Story: Ovarian cancer, for which effective screening is lacking, is the most lethal gynecologic malignancy. Major hurdles in combating the disease include inevitable recurrence and eventual chemotherapeutic resistance. While platinum-based therapy and PARP inhibitors remain the mainstay of initial treatment, novel therapeutic agents aimed at targeting mechanisms of resistance have emerged, offering new opportunities for treatment in the recurrent setting. This review addresses these novel therapeutics and the evolving treatment landscape of ovarian cancer. View this paper
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Articles (43)
- Article
5 Citations
2,589 Views
10 Pages
Primary Mucosal Melanoma: Clinical Experience from a Single Italian Center
- Rosa Falcone,
- Sofia Verkhovskaia,
- Francesca Romana Di Pietro,
- Giulia Poti,
- Tonia Samela,
- Maria Luigia Carbone,
- Maria Francesca Morelli,
- Albina Rita Zappalà,
- Zorika Christiana di Rocco and
- Roberto Morese
- + 4 authors
(1) Background: Mucosal melanoma (MM) is a rare tumor, accounting for about 1% of all diagnosed melanomas. The etiology and pathogenesis of this tumor are unknown. It is characterized by an aggressive phenotype with poor prognosis and a low response...
- Case Report
1 Citations
2,807 Views
9 Pages
Primary Diffuse Leptomeningeal Melanomatosis in a Child with Extracranial Metastasis: Case Report
- Shubin W. Shahab,
- Prabhumallikarjun Patil,
- Jason R. Fangusaro,
- Brooke Patteson,
- Adam Goldman-Yassen,
- Bree R. Eaton,
- William Boydston,
- Matthew Schniederjan and
- Dolly Aguilera
Primary meningeal melanomatosis is an extremely rare tumor with very few documented responses to treatment. A 3-year-old male with a complex past medical history, including prematurity and shunted hydrocephalus, was diagnosed with primary meningeal m...
- Systematic Review
9 Citations
2,860 Views
13 Pages
A Systematic Review of Adjuvant Chemotherapy in Localized Dedifferentiated Chondrosarcoma
- Shinji Tsukamoto,
- Andreas F. Mavrogenis,
- Yuji Nitta,
- Alberto Righi,
- Tomoya Masunaga,
- Kanya Honoki,
- Hiromasa Fujii,
- Akira Kido,
- Yuu Tanaka and
- Yasuhito Tanaka
- + 1 author
Dedifferentiated chondrosarcoma (DDCS) is a high-grade subtype of chondrosarcoma with the bimorphic histological appearance of a conventional chondrosarcoma component with abrupt transition to a high-grade, non-cartilaginous sarcoma. DDCS can be radi...
- Case Report
2 Citations
2,470 Views
8 Pages
Combination of Osimertinib and Olaparib Therapy to Treat Non-Small Cell Lung Cancer and High-Grade Serous Ovarian Carcinoma: A Case Report
- Jane Lin,
- Stephen Welch,
- Michael Sanatani and
- Sherif Ramadan
We present the case of a 75-year-old female with simultaneous EGFR-mutated stage IV lung cancer and advanced BRCA2-mutated ovarian cancer, treated with a unique regimen. In this case report, the patient was treated with alternating months of osimerti...
- Article
2 Citations
2,530 Views
11 Pages
Comparative Analysis of Subclassification Systems in Patients with Intermediate-Stage Hepatocellular Carcinoma (Barcelona Clinic Liver Classification B) Receiving Systemic Therapy
- Luca Ielasi,
- Bernardo Stefanini,
- Fabio Conti,
- Matteo Tonnini,
- Raffaella Tortora,
- Giulia Magini,
- Rodolfo Sacco,
- Tiziana Pressiani,
- Franco Trevisani and
- Francesco Giuseppe Foschi
- + 3 authors
Background: Intermediate-stage hepatocellular carcinoma (BCLC B HCC) occurs in a heterogeneous group of patients and can be addressed with a wide spectrum of treatments. Consequently, survival significantly varies among patients. In recent years, sev...
- Article
3 Citations
2,265 Views
12 Pages
Artemis as Predictive Biomarker of Responsiveness to Preoperative Chemoradiotherapy in Patients with Locally Advanced Rectal Cancer
- Hai Liu,
- Runying Huang,
- Jingjing Shan,
- Xuyun Xie,
- Chongwei Wang,
- Peng Hu and
- Xiaonan Sun
The aim of this study was to identify Artemis as a predictive biomarker for guiding preoperative chemoradiotherapy in locally advanced rectal cancer. The resection specimens were collected from 50 patients with rectal cancer who underwent preoperativ...
- Article
1 Citations
2,643 Views
14 Pages
Comparison of 68Ga-DOTATATE Positron Emmited Tomography/Computed Tomography and Gadoxetic Acid-Enhanced Magnetic Resonance Imaging for the Detection of Liver Metastases from Well-Differentiated Neuroendocrine Tumors
- Moran Drucker Iarovich,
- Ricarda Hinzpeter,
- Brian Michael Moloney,
- Katrina Hueniken,
- Patrick Veit-Haibach,
- Claudia Ortega and
- Ur Metser
This study aimed to compare the detection of neuroendocrine tumor liver metastases (NLMs) in hepatobiliary-specific contrast-enhanced MRI (pMR) versus 68Ga-DOTATATE PET/CT (DT-PET). This retrospective study cohort included 30 patients with well-diffe...
- Article
5 Citations
3,215 Views
10 Pages
Cavity Shave Margins in Breast Conservative Surgery a Strategy to Reduce Positive Margins and Surgical Time
- Gianluca Vanni,
- Marco Pellicciaro,
- Giulia Renelli,
- Marco Materazzo,
- Amir Sadri,
- Valentina Enrica Marsella,
- Federico Tacconi,
- Sebastiano Angelo Bastone,
- Benedetto Longo and
- Giordana Di Mauro
- + 3 authors
Background: Resection of additional tissue circumferentially around the cavity left by lumpectomy (cavity shave) was suggested to reduce rates of positive margins and re-excision. Methods: A single center retrospective study which analyzed margins st...
- Article
2 Citations
4,251 Views
10 Pages
Impact of a Best Practices Program in Patients with Relapsed/Refractory Multiple Myeloma Receiving Selinexor
- Lucio N. Gordan,
- David Ray,
- Stephen C. Ijioma,
- George Dranitsaris,
- Amanda Warner,
- Trevor Heritage,
- Matthew Fink,
- David Wenk,
- Paul Chadwick and
- Natasha Khrystolubova
- + 1 author
Best practice (BP) in cancer care consists of a multifaceted approach comprising individualized treatment plans, evidence-based medicine, the optimal use of supportive care and patient education. We investigated the impact of a BP program in patients...
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Curr. Oncol. - ISSN 1718-7729