Current Oncology, Volume 19, Issue 2

The use of systemic therapy before surgery (“neoadjuvant therapy”) is the standard of care for the treatment of locally advanced and nonoperable breast cancer. The advantages of neoadjuvant therapy include improved rates of breast-conserving surgery,...

Epidemiologic observations in two fields of study lead to the same conclusion: namely, that a proportion of breast cancers will go away without medical or surgical intervention[...].

In 2011, Current Oncology launched a new standing section, Knowledge Translation, to improve cancer control in Canada ¹[...].

Although orthodox medicine trains general medical practitioners to comprehensively treat the whole patient and to refer to specialists only when patients present ailments exceeding the knowledge and skills of the practitioner, specialists continually...

Background: Of all mastectomy patients, 90% will use an external prosthesis where the standard of care uses a stock prosthesis that is purchased “off the shelf.” Our objectives were to determine patient demand for and perceived value of a custom brea...

Background: In 2006, the federal government committed funding of $250 million over 5 years for the Canadian Partnership Against Cancer Corporation to begin implementation of the Canadian Strategy for Cancer Control (cscc). The Partnership was establi...

Lung cancer is one of the most commonly diagnosed malignancies and the leading cause of cancer-related mortality in Canada. The heterogeneity of nsclc and the importance of linking new targeted agents to the appropriate disease subtype require an ind...

This article provides an overview of recent advances in chemotherapy that may be used for the treatment of patients with locally advanced or metastatic breast cancer (mbc). Key phase ii and iii trial data for eribulin mesylate, ixabepilone, and nab-p...

Background: Of all mastectomy patients, 90% will use an external prosthesis where the standard of care uses a stock prosthesis that is purchased “off the shelf.” Our objectives were to determine patient demand for and perceived value of a custom brea...

Context: The delineation of populations of cancer patients with complex symptoms can inform the planning and delivery of supportive care services. Objectives: We explored the physical, psychosocial, and practical concerns experienced by patients atte...

Background: The palliation of dysphagia in metastatic esophageal cancer remains a challenge, and the optimal approach for this difficult clinical scenario is not clear. We therefore sought to define and determine the efficacy of various treatment opt...

Background: Non-small-cell lung cancer (NSCLC) tumours with activating mutations of the epidermal growth factor receptor (EFGR) tyrosine kinase are highly sensitized to the effects of oral tyrosine kinase inhibitors such as gefitinib and erlotinib, s...

Background: This phase II clinical trial examined the activity of a metronomic dosing schedule of docetaxel and capecitabine chemotherapy in patients with advanced breast cancer. Patients also received daily oral celecoxib in an effort to improve out...

Background: Nearly 15% of DNA tests for BRCA1/2 results in the identification of an unclassified variant (UV). In DNA diagnostic laboratories in The Netherlands, a 4-group classification system (class I to IV) is in use (Bell et al.). Aim of this stu...