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Marine Drugs, Volume 20, Issue 3

March 2022 - 63 articles

Cover Story: Species misidentification in sponge natural products is an acknowledged problem. In this case study, we report isomalabaricane triterpenes, isolated from four demosponge genera: Jaspis, Geodia, Stelletta and Rhabdastrella from 44 articles (1981–2022). Overall, 65.9% of the studies published an incorrect species name: previously identified Jaspis and Stelletta species were certainly Rhabdastrella globostellata. We conclude that isomalabaricane triterpenes were isolated from only two Rhabdastrella species and possibly one Geodia species. This study highlights the importance of vouchers to revisit chemotaxonomy issues and ensure reproducibility of studies. A common protocol of good practice in sponge natural product studies is suggested. View this paper
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Articles (63)

  • Review
  • Open Access
49 Citations
7,419 Views
18 Pages

Exploring Marine as a Rich Source of Bioactive Peptides: Challenges and Opportunities from Marine Pharmacology

  • Ishtiaq Ahmed,
  • Muhammad Asgher,
  • Farooq Sher,
  • Syed Makhdoom Hussain,
  • Nadia Nazish,
  • Navneet Joshi,
  • Ashutosh Sharma,
  • Roberto Parra-Saldívar,
  • Muhammad Bilal and
  • Hafiz M. N. Iqbal

13 March 2022

This review highlights the underexplored potential and promises of marine bioactive peptides (MBPs) with unique structural, physicochemical, and biological activities to fight against the current and future human pathologies. A particular focus is gi...

  • Article
  • Open Access
20 Citations
4,493 Views
17 Pages

12 March 2022

This work studied the potential biotechnological applications of a naviculoid diatom (IMA053) and a green microalga (Tetraselmis marina IMA043) isolated from the North Adriatic Sea. Water, methanol, and dichloromethane (DCM) extracts were prepared fr...

  • Review
  • Open Access
73 Citations
11,375 Views
22 Pages

Astaxanthin from Crustaceans and Their Byproducts: A Bioactive Metabolite Candidate for Therapeutic Application

  • Vida Šimat,
  • Nikheel Bhojraj Rathod,
  • Martina Čagalj,
  • Imen Hamed and
  • Ivana Generalić Mekinić

12 March 2022

In recent years, the food, pharma, and cosmetic industries have shown considerable interest in bioactive molecules of marine origin that show high potential for application as nutraceuticals and therapeutic agents. Astaxanthin, a lipid-soluble and or...

  • Article
  • Open Access
1 Citations
4,177 Views
11 Pages

Evaluation of the Preservation and Digestion of Seal Meat Processed with Heating and Antioxidant Seal Meat Hydrolysates

  • Yi Zhang,
  • Lea Spitzer,
  • Xin Rui,
  • Susana C. M. Fernandes,
  • Romy Vaugeois and
  • Benjamin K. Simpson

10 March 2022

Seal meat is of high nutritive value but is not highly exploited for human food due to ethical issues, undesirable flavors, and loss of nutrients during the processing/cooking step. In this work, commercially available processed seal meat was treated...

  • Article
  • Open Access
9 Citations
3,996 Views
14 Pages

10 March 2022

Wound healing is a highly orchestrated process involving many cell types, such as keratinocytes, fibroblasts and endothelial cells. This study aimed to evaluate the potential application of synthetic peptides derived from tilapia piscidin (TP)2, TP2-...

  • Article
  • Open Access
5 Citations
3,302 Views
14 Pages

10 March 2022

Through activity-guided fractionation, a new triterpene (asperflagin, 1) was isolated as a PPAR-γ agonist from the jellyfish-derived fungus Aspergillus flavus. Asperflagin displayed selective and moderate transactivation effects on PPAR-γ...

  • Review
  • Open Access
43 Citations
8,637 Views
17 Pages

10 March 2022

The high-valued utilization of Ulva (previously known as Enteromorpha) bioresources has drawn increasing attention due to the periodic blooms of world-wide green tide. The polysaccharide is the main functional component of Ulva and exhibits various p...

  • Article
  • Open Access
10 Citations
4,186 Views
18 Pages

9 March 2022

Hematopoietic damage is a serious side effect of cytotoxic drugs, and agents promoting hematopoiesis are quite important for decreasing the death rate in cancer patients. In our previous work, we prepared the simulated digestive product of fucoidan f...

  • Article
  • Open Access
11 Citations
5,457 Views
18 Pages

9 March 2022

The α7 nicotinic acetylcholine receptor (nAChR) is widely distributed in the central and peripheral nervous systems and is closely related to a variety of nervous system diseases and inflammatory responses. The α7 nAChR subtype plays a vi...

  • Review
  • Open Access
32 Citations
6,671 Views
25 Pages

8 March 2022

Harmful algal blooms pose a challenge regarding food safety due to their erratic nature and forming circumstances which are yet to be disclosed. The best strategy to protect human consumers is through legislation and monitoring strategies. Global war...

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Mar. Drugs - ISSN 1660-3397Creative Common CC BY license