Mar. Drugs, Volume 18, Issue 4 (April 2020) – 51 articles
Cover Story (view full-size image): Phylum Cnidaria, the oldest extant venomous lineage, is distinguished from other venomous phyla in that venom production often occurs throughout the entire organism. In this review, we examine how the functional role of tissues and the ecological context influence the temporal and spatial expression of toxins. Understanding the nuances of venom production has been made possible by recent advances in analytical technologies that allow us to map the spatial distribution of toxins. Furthermore, cnidarians are unique in that the ecological role of toxins can be assigned using tissue function, thereby, circumventing some of the challenges related to pharmacological screening. View this paper.
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