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Pharmaceuticals, Volume 9, Issue 1

March 2016 - 16 articles

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Articles (16)

  • Meeting Report
  • Open Access
1 Citations
10,810 Views
56 Pages

11th National Meeting of Organic Chemistry and 4th Meeting of Therapeutic Chemistry

  • Maria Emília Sousa,
  • Maria João Araújo,
  • Maria Luísa Do Vale,
  • Paula B. Andrade,
  • Paula Branco,
  • Paula Gomes,
  • Rui Moreira,
  • Teresa M.V.D. Pinho e Melo and
  • Victor Freitas

For the first time under the auspices of Sociedade Portuguesa de Química, the competences of two important fields of Chemistry are brought together into a single event, the 11st National Organic Chemistry Meeting and the the 4th National Medicinal Ch...

  • Article
  • Open Access
32 Citations
6,632 Views
16 Pages

Activity of Gallium Meso- and Protoporphyrin IX against Biofilms of Multidrug-Resistant Acinetobacter baumannii Isolates

  • David Chang,
  • Rebecca A. Garcia,
  • Kevin S. Akers,
  • Katrin Mende,
  • Clinton K. Murray,
  • Joseph C. Wenke and
  • Carlos J. Sanchez

Acinetobacter baumannii is a challenging pathogen due to antimicrobial resistance and biofilm development. The role of iron in bacterial physiology has prompted the evaluation of iron-modulation as an antimicrobial strategy. The non-reducible iron an...

  • Meeting Report
  • Open Access
2 Citations
8,248 Views
27 Pages

The first International Electronic Conference on Medicinal Chemistry, organized and sponsored by MDPI AG, publisher, and the Journal Pharmaceuticals, took place in November 2015 on the SciForum website. More than 200 authors from 18 countries partici...

  • Review
  • Open Access
49 Citations
15,808 Views
35 Pages

Potential Use of Antimicrobial Peptides as Vaginal Spermicides/Microbicides

  • Nongnuj Tanphaichitr,
  • Nopparat Srakaew,
  • Rhea Alonzi,
  • Wongsakorn Kiattiburut,
  • Kessiri Kongmanas,
  • Ruina Zhi,
  • Weihua Li,
  • Mark Baker,
  • Guanshun Wang and
  • Duane Hickling

The concurrent increases in global population and sexually transmitted infection (STI) demand a search for agents with dual spermicidal and microbicidal properties for topical vaginal application. Previous attempts to develop the surfactant spermicid...

  • Short Note
  • Open Access
8 Citations
7,063 Views
7 Pages

Treatment of patients with acute myeloid leukemia (AML) who do not wish to accept blood product transfusion, including Jehovah’s Witnesses, is extremely challenging. The use of conventional chemotherapy for induction of complete remission (CR) result...

  • Commentary
  • Open Access
5 Citations
4,428 Views
3 Pages

25 February 2016

This brief commentary aims to focus on the urgency of further clinical research on phytotherapy in dentistry, and, noteworthy, to propose, for the first time, to the best of our knowledge, the term “odontonutraceuticals” to identify those phytochemic...

  • Review
  • Open Access
38 Citations
8,988 Views
26 Pages

Targeting Cell Survival Proteins for Cancer Cell Death

  • Manoj K. Pandey,
  • Sahdeo Prasad,
  • Amit Kumar Tyagi,
  • Lokesh Deb,
  • Jiamin Huang,
  • Deepkamal N. Karelia,
  • Shantu G. Amin and
  • Bharat B. Aggarwal

25 February 2016

Escaping from cell death is one of the adaptations that enable cancer cells to stave off anticancer therapies. The key players in avoiding apoptosis are collectively known as survival proteins. Survival proteins comprise the Bcl-2, inhibitor of apopt...

  • Review
  • Open Access
68 Citations
13,453 Views
42 Pages

Cognitive Dysfunction in Major Depressive Disorder. A Translational Review in Animal Models of the Disease

  • Flavie Darcet,
  • Alain M. Gardier,
  • Raphael Gaillard,
  • Denis J. David and
  • Jean-Philippe Guilloux

17 February 2016

Major Depressive Disorder (MDD) is the most common psychiatric disease, affecting millions of people worldwide. In addition to the well-defined depressive symptoms, patients suffering from MDD consistently complain about cognitive disturbances, signi...

  • Article
  • Open Access
14 Citations
6,172 Views
9 Pages

6 February 2016

Propofol is a widely used general anaesthetic with muscle relaxant properties. Similarly as propofol, the new general anaesthetic AZD3043 targets the GABAA receptor for its anaesthetic effects, but the interaction with nicotinic acetylcholine recepto...

  • Article
  • Open Access
26 Citations
9,253 Views
13 Pages

Biomolecules and Natural Medicine Preparations: Analysis of New Sources of Bioactive Compounds from Ribes and Rubus spp. Buds

  • Dario Donno,
  • Maria Gabriella Mellano,
  • Alessandro Kim Cerutti and
  • Gabriele Loris Beccaro

5 February 2016

It is well known that plants are important sources for the preparation of natural remedies as they contain many biologically active compounds. In particular, polyphenols, terpenic compounds, organic acids, and vitamins are the most widely occurring g...

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Pharmaceuticals - ISSN 1424-8247