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International Journal of Molecular Sciences, Volume 13, Issue 2

February 2012 - 80 articles

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Articles (80)

  • Review
  • Open Access
80 Citations
11,553 Views
19 Pages

Impaired Iron Status in Aging Research

  • Jinze Xu,
  • Zhenhua Jia,
  • Mitchell D. Knutson and
  • Christiaan Leeuwenburgh

22 February 2012

Aging is associated with disturbances in iron metabolism and storage. During the last decade, remarkable progress has been made toward understanding their cellular and molecular mechanisms in aging and age-associated diseases using both cultured cell...

  • Article
  • Open Access
12 Citations
7,310 Views
18 Pages

22 February 2012

Kinase insert domain receptor (KDR) inhibitors have been proved to be very effective anticancer agents. Molecular docking, 3D-QSAR methods, CoMFA and CoMSIA were performed on pyrrolo[3,2-d]pyrimidine derivatives as non-ATP competitive KDR inhibitors...

  • Article
  • Open Access
41 Citations
10,026 Views
20 Pages

Characterization of Different Functionalized Lipidic Nanocapsules as Potential Drug Carriers

  • Paola Sánchez-Moreno,
  • Juan Luis Ortega-Vinuesa,
  • Antonio Martín-Rodríguez,
  • Houría Boulaiz,
  • Juan Antonio Marchal-Corrales and
  • José Manuel Peula-García

22 February 2012

Lipid nanocapsules (LNC) based on a core-shell structure consisting of an oil-filled core with a surrounding polymer layer are known to be promising vehicles for the delivery of hydrophobic drugs in the new therapeutic strategies in anti-cancer treat...

  • Article
  • Open Access
5 Citations
8,502 Views
14 Pages

DNA Barcodes of Asian Houbara Bustard (Chlamydotis undulata macqueenii)

  • Ibrahim A. Arif,
  • Haseeb A. Khan,
  • Joseph B. Williams,
  • Mohammad Shobrak and
  • Waad I. Arif

22 February 2012

Populations of Houbara Bustards have dramatically declined in recent years. Captive breeding and reintroduction programs have had limited success in reviving population numbers and thus new technological solutions involving molecular methods are esse...

  • Article
  • Open Access
39 Citations
10,522 Views
20 Pages

Enhancing Osteoconduction of PLLA-Based Nanocomposite Scaffolds for Bone Regeneration Using Different Biomimetic Signals to MSCs

  • Gabriela Ciapetti,
  • Donatella Granchi,
  • Valentina Devescovi,
  • Serena R. Baglio,
  • Elisa Leonardi,
  • Desirèe Martini,
  • Maria Jesus Jurado,
  • Beatriz Olalde,
  • Ilaria Armentano and
  • Josè M. Kenny
  • + 3 authors

22 February 2012

In bone engineering, the adhesion, proliferation and differentiation of mesenchymal stromal cells rely on signaling from chemico-physical structure of the substrate, therefore prompting the design of mimetic “extracellular matrix”-like scaffolds. In...

  • Article
  • Open Access
19 Citations
7,237 Views
13 Pages

22 February 2012

Circular dichroism (CD) and deconvolution were used to study the structural integrity of a “plugged” and an “open” FhuA transmembrane channel protein in the presence of varied concentrations of tetrahydrofuran (THF), ethanol (EtOH) and chloroform/met...

  • Article
  • Open Access
108 Citations
14,595 Views
9 Pages

Antioxidant Activity of Mulberry Fruit Extracts

  • Muhammad Arfan,
  • Rasool Khan,
  • Anna Rybarczyk and
  • Ryszard Amarowicz

22 February 2012

Phenolic compounds were extracted from the fruits of Morus nigra and Morus alba using methanol and acetone. The sugar-free extracts (SFEs) were prepared using Amberlite XAD-16 column chromatography. All of the SFEs exhibited antioxidant potential as...

  • Article
  • Open Access
107 Citations
12,779 Views
20 Pages

22 February 2012

Lipoxygenases (LOXs) are non-haem iron-containing dioxygenases that catalyse oxygenation of polyunsaturated fatty acids and lipids to initiate the formation of a group of biologically active compounds called oxylipins. Plant oxylipins play important...

  • Article
  • Open Access
6 Citations
6,529 Views
14 Pages

Spectroscopic Parameter and Molecular Constant Investigations on Low-Lying States of BeF Radical

  • Zun Lue Zhu,
  • Qing Peng Song,
  • Su Hua Kou,
  • Jian Hua Lang and
  • Jin Feng Sun

22 February 2012

The potential energy curves (PECs) of X2Σ+, A2Πr and B2Σ+ states of BeF radical have been investigated using the complete active space self-consistent-field (CASSCF) method, followed by the highly accurate valence internally contracted multireference...

  • Communication
  • Open Access
4 Citations
6,574 Views
6 Pages

Isolation and Characterization of New Microsatellite Markers for the Invasive Softshell Clam, Mya arenaria (L.) (Bivalvia: Myidae)

  • Ana-Maria Krapal,
  • Oana Paula Popa,
  • Elena Iulia Iorgu,
  • Marieta Costache and
  • Luis Ovidiu Popa

22 February 2012

The invasive softshell clam (Mya arenaria Linnaeus, 1758) is native to the northwestern region of the Atlantic Ocean. This species has been introduced in the northeast Pacific and along the European coasts, due to intense naval transports and aquacul...

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Int. J. Mol. Sci. - ISSN 1422-0067