Next Article in Journal
The Effect of Toll-Like Receptor 4 in the Aqueous Humor of Endotoxin-Induced Uveitis
Previous Article in Journal
Neuroprotective Effects of Pre-Treament with l-Carnitine and Acetyl-l-Carnitine on Ischemic Injury In Vivo and In Vitro
Previous Article in Special Issue
Fabrication, Modeling and Characterization of Multi-Crosslinked Methacrylate Copolymeric Nanoparticles for Oral Drug Delivery
Article Menu

Export Article

Open AccessReview
Int. J. Mol. Sci. 2012, 13(2), 2091-2109;

Antioxidant-Induced Stress

Escuela Superior de Medicina del IPN, Posgrado e Investigacion, Plan de San Luis y Salvador Diaz Miron S/N, Colonia Casco de Santo Tomas, Mexico, DF. 11340, Mexico
Kross-Link Laboratories, Bellmore, NY 11710, USA
Author to whom correspondence should be addressed.
Received: 19 December 2011 / Revised: 30 January 2012 / Accepted: 13 February 2012 / Published: 16 February 2012
(This article belongs to the Special Issue Bioactive Nanoparticles (special issue))
Full-Text   |   PDF [357 KB, uploaded 19 June 2014]   |  


Antioxidants are among the most popular health-protecting products, sold worldwide without prescription. Indeed, there are many reports showing the benefits of antioxidants but only a few questioning the possible harmful effects of these “drugs”. The normal balance between antioxidants and free radicals in the body is offset when either of these forces prevails. The available evidence on the harmful effects of antioxidants is analyzed in this review. In summary, a hypothesis is presented that “antioxidant-induced stress” results when antioxidants overwhelm the body’s free radicals. View Full-Text
Keywords: antioxidant; oxidative stress; harmful effects antioxidant; oxidative stress; harmful effects

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Villanueva, C.; Kross, R.D. Antioxidant-Induced Stress. Int. J. Mol. Sci. 2012, 13, 2091-2109.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top