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Entropy, Volume 23, Issue 1

January 2021 - 128 articles

Cover Story: Permeation through a potassium channel is quickly terminated after it opens via selectivity filter inactivation. This process is essential to functioning potassium channels, including bacterial KcsA. We compared the behavior of the wild-type KcsA channel and its mutants using molecular dynamic simulations, identifying residues with distinct properties. By analyzing causal links between rearrangements of these residues and permeating ions, we unraveled a network that acts as a self-organized system in regulating the ion permeation. Changes in one part of the network can lead to an adaptation in other regions, and the network can dynamically switch to an inactive state. View this paper.
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Articles (128)

  • Article
  • Open Access
4 Citations
3,458 Views
19 Pages

Variationally Inferred Sampling through a Refined Bound

  • Víctor Gallego and
  • David Ríos Insua

19 January 2021

In this work, a framework to boost the efficiency of Bayesian inference in probabilistic models is introduced by embedding a Markov chain sampler within a variational posterior approximation. We call this framework “refined variational approxim...

  • Review
  • Open Access
2 Citations
4,035 Views
25 Pages

19 January 2021

We study dynamics and thermodynamics of ion transport in narrow, water-filled channels, considered as effective 1D Coulomb systems. The long range nature of the inter-ion interactions comes about due to the dielectric constants mismatch between the w...

  • Article
  • Open Access
33 Citations
5,203 Views
28 Pages

19 January 2021

Meta-learning, or “learning to learn”, refers to techniques that infer an inductive bias from data corresponding to multiple related tasks with the goal of improving the sample efficiency for new, previously unobserved, tasks. A key perfo...

  • Article
  • Open Access
4,077 Views
19 Pages

19 January 2021

Recently, there has been a resurgence of formal language theory in deep learning research. However, most research focused on the more practical problems of attempting to represent symbolic knowledge by machine learning. In contrast, there has been li...

  • Article
  • Open Access
19 Citations
4,241 Views
18 Pages

19 January 2021

In the fault monitoring of rotating machinery, the vibration signal of the bearing and gear in a complex operating environment has poor stationarity and high noise. How to accurately and efficiently identify various fault categories is a major challe...

  • Article
  • Open Access
26 Citations
4,235 Views
12 Pages

18 January 2021

Automatic sleep staging with only one channel is a challenging problem in sleep-related research. In this paper, a simple and efficient method named PPG-based multi-class automatic sleep staging (PMSS) is proposed using only a photoplethysmography (P...

  • Feature Paper
  • Review
  • Open Access
13 Citations
7,828 Views
27 Pages

Probabilistic Models with Deep Neural Networks

  • Andrés R. Masegosa,
  • Rafael Cabañas,
  • Helge Langseth,
  • Thomas D. Nielsen and
  • Antonio Salmerón

18 January 2021

Recent advances in statistical inference have significantly expanded the toolbox of probabilistic modeling. Historically, probabilistic modeling has been constrained to very restricted model classes, where exact or approximate probabilistic inference...

  • Article
  • Open Access
17 Citations
4,802 Views
38 Pages

18 January 2021

The possibilities of applying the pure Lagrangian vortex methods of computational fluid dynamics to viscous incompressible flow simulations are considered in relation to various problem formulations. The modification of vortex methods—the Visco...

  • Article
  • Open Access
252 Citations
16,000 Views
13 Pages

Automatic ECG Classification Using Continuous Wavelet Transform and Convolutional Neural Network

  • Tao Wang,
  • Changhua Lu,
  • Yining Sun,
  • Mei Yang,
  • Chun Liu and
  • Chunsheng Ou

18 January 2021

Early detection of arrhythmia and effective treatment can prevent deaths caused by cardiovascular disease (CVD). In clinical practice, the diagnosis is made by checking the electrocardiogram (ECG) beat-by-beat, but this is usually time-consuming and...

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Entropy - ISSN 1099-4300