Topic Editors

Department of Chemistry, University Khyber Pakhtunkhwa, Swabi 490500, Pakistan
Dr. Mujeeb Ur Rehman
L.E.J. Nanotechnology Center, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan

Preparation and Antibacterial Properties of Metal Nanoparticles

Abstract submission deadline
closed (30 November 2023)
Manuscript submission deadline
closed (20 February 2024)
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33983

Topic Information

Dear Colleagues,

Earlier metallic nanoparticles (NPs) have been reported for several medical applications. Developments in modern medicine have increased the usage of metallic NPs for medical purposes due to their broad spectrum of biological properties such as anti-fungal, antibacterial, antioxidant, antiviral, analgesic, muscle relaxant, antiangiogenic, and anti-inflammatory activity. In this issue, metal nanoparticles will be presented broadly as prevailing nanomaterials for the eradication of bacteria and/or bacterial infections. The current finding gives an indication that metal-based nanoparticles are very effective in supporting antibacterial potential. Chemically and laser-ablated gold, silver, copper, and iron nanoparticles possess promising antibacterial activity. Metallic nanoparticles (NPs) showed good performance, chemically, physically, and catalytically. This issue will deal with details of the preparation, characterization, and antibacterial activities of different metallic nanoparticles (gold, silver, iron, copper, etc.).

We are pleased to invite all researchers and research teams that are interested in the field of preparation and the antibacterial properties of metal nanoparticles to contribute to this Topic with their manuscript(s). Full original research papers, short communications, and reviews regarding this topic are all welcome.

Dr. Abdur Rauf
Dr. Mujeeb Ur Rehman
Topic Editors

Keywords

  • gold nanoparticles
  • silver nanoparticles
  • copper nanoparticles
  • iron nanoparticles
  • antibacterial activities

Participating Journals

Journal Name Impact Factor CiteScore Launched Year First Decision (median) APC
Materials
materials
3.1 5.8 2008 15.5 Days CHF 2600
Nanomaterials
nanomaterials
4.4 8.5 2010 13.8 Days CHF 2900
Applied Sciences
applsci
2.5 5.3 2011 17.8 Days CHF 2400
Metals
metals
2.6 4.9 2011 16.5 Days CHF 2600
Crystals
crystals
2.4 4.2 2011 10.8 Days CHF 2100

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Published Papers (12 papers)

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13 pages, 14454 KiB  
Article
Writing Tiny Nanoclusters Using a Nanofountain Pen Operated by Spontaneous Evaporation
by Sung-Jo Kim, Dongwon Yi, Il Hyun Lee, Won-Geun Kim, Ye-Ji Kim, Jong-Sik Moon and Jin-Woo Oh
Crystals 2024, 14(1), 9; https://doi.org/10.3390/cryst14010009 - 21 Dec 2023
Viewed by 1254
Abstract
Tow-dimensional and 3-dimensional colloidal structures have been used to study surface-enhanced Raman scattering and localized surface plasmon resonance because of their regular stacking structures. However, freely controlling the number and size of the colloidal assemblies remains a challenge. In this study, we demonstrated [...] Read more.
Tow-dimensional and 3-dimensional colloidal structures have been used to study surface-enhanced Raman scattering and localized surface plasmon resonance because of their regular stacking structures. However, freely controlling the number and size of the colloidal assemblies remains a challenge. In this study, we demonstrated the fabrication and mechanism of tiny nanoclusters using spontaneous evaporation-based nanofountain pens (NFPs). A micrometer-scale NFP nozzle was fabricated using a glass capillary. The gold nanoparticles (AuNPs) dispersed ink formed the pendant droplet at the NFP nozzle tip, where the AuNPs accumulated within the pendant droplet because of evaporation. The accumulated AuNPs were transferred onto the substrate via a stamp-like process to create nanoclusters. Using water evaporation analyzed by diffusion equations, we showed that reducing the AuNP accumulation to one hundred is possible. This precise adjustment enables fabrication until submicrometer-level nanoclusters. The fabrication method using NFPs can create 3D structures, and this operation is not significantly affected by the size or composition of the AuNPs. This could be expanded to metabolite-included nanocluster where metabolite can be located at the hot spot among AuNPs. Therefore, we expect that this will be utilized to create SERS signals and conduct disease diagnosis research using extremely small amounts of metabolites. Full article
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16 pages, 3483 KiB  
Article
Adenosine-Monophosphate-Assisted Homogeneous Silica Coating of Silver Nanoparticles in High Yield
by Carlos Fernández-Lodeiro, Reem Tambosi, Javier Fernández-Lodeiro, Adrián Fernández-Lodeiro, Silvia Nuti, Soufian Ouchane, Nouari Kébaïli, Jorge Pérez-Juste, Isabel Pastoriza-Santos and Carlos Lodeiro
Nanomaterials 2023, 13(20), 2788; https://doi.org/10.3390/nano13202788 - 18 Oct 2023
Cited by 3 | Viewed by 2049
Abstract
In this study, we propose a novel approach for the silica coating of silver nanoparticles based on surface modification with adenosine monophosphate (AMP). Upon AMP stabilization, the nanoparticles can be transferred into 2-propanol, promoting the growth of silica on the particle surfaces through [...] Read more.
In this study, we propose a novel approach for the silica coating of silver nanoparticles based on surface modification with adenosine monophosphate (AMP). Upon AMP stabilization, the nanoparticles can be transferred into 2-propanol, promoting the growth of silica on the particle surfaces through the standard Stöber process. The obtained silica shells are uniform and homogeneous, and the method allows a high degree of control over shell thickness while minimizing the presence of uncoated NPs or the negligible presence of core-free silica NPs. In addition, AMP-functionalized AgNPs could be also coated with a mesoporous silica shell using cetyltrimethylammonium chloride (CTAC) as a template. Interestingly, the thickness of the mesoporous silica coating could be tightly adjusted by either the silica precursor concentration or by varying the CTAC concentration while keeping the silica precursor concentration constant. Finally, the influence of the silica coating on the antimicrobial effect of AgNPs was studied on Gram-negative bacteria (R. gelatinosus and E. coli) and under different bacterial growth conditions, shedding light on their potential applications in different biological environments. Full article
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16 pages, 3154 KiB  
Article
Biological Synthesis of Copper Nanoparticles Using Edible Plant Allium monanthum: Characterization of Antibacterial, Antioxidant, and Anti-Inflammatory Properties Using In Silico Molecular Docking Analysis
by Hyo Shim Han, Jeong Sung Jung, Young-Il Jeong and Ki Choon Choi
Materials 2023, 16(20), 6669; https://doi.org/10.3390/ma16206669 - 12 Oct 2023
Cited by 1 | Viewed by 1719
Abstract
This study prepared copper nanoparticles using an edible leaf extract from A. monanthum (AM-CuNPs) via eco-friendly green synthesis techniques. The size, shape, crystalline nature and functional groups of the synthesized AM-CuNP particles were analyzed by a UV-VIS spectrophotometer and SEM, EDX, TEM, XRD [...] Read more.
This study prepared copper nanoparticles using an edible leaf extract from A. monanthum (AM-CuNPs) via eco-friendly green synthesis techniques. The size, shape, crystalline nature and functional groups of the synthesized AM-CuNP particles were analyzed by a UV-VIS spectrophotometer and SEM, EDX, TEM, XRD and FT-IR instrumentation. The synthesized AM-CuNPs had spherical shapes with sizes in the range of 30–80 nm and were crystalline in nature. In addition, the AM-CuNPs were synthesized using various bioactive sources, including flavonoids, phenolic acids, alkaloids and sugars that were present in an aqueous broth of A. monanthum. Furthermore, the AM-CuNPs possessed good antibacterial properties against selected major disease-causing pathogenic bacteria, such as E. coli, Salmonella typhi, Pseudomonas aeruginosa and Staphylococcus aureus. The antioxidant activity of AM-CuNPs exhibited potent free radical scavenging activities in DPPH, ABTS and H2O2 radical assays. In addition, in silico analysis of the AM-CuNPs was performed, including ADME prediction, and molecular simulation docking on the secondary metabolites identified in the edible plant extract was used to evaluate their anti-inflammatory applications. In particular, the molecular docking scores showed that alliin, apigenin, isorhamnetin, luteolin and myricetin have sufficient binding energy and top values as inhibitors of the protein target involved in the inflammation signaling cascade. Full article
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14 pages, 4439 KiB  
Article
Synthesis, Characterization, and Antibacterial Assessment (Synergism) of Silver Nanoparticles Prepared with Stem Bark Extract of Sterculia diversifolia
by Fazle Rabbi, Imad Ahmad, Amna Nisar, Abdur Rauf, Abdulrahman Alshammari, Metab Alharbi and Hafiz Ansar Rasul Suleria
Crystals 2023, 13(3), 480; https://doi.org/10.3390/cryst13030480 - 10 Mar 2023
Cited by 1 | Viewed by 1935
Abstract
Microbial infections present a challenging arena to the modern world. Traditional antibiotics are now familiar to microbes. To counter this microbial familiarity, a novel approach is a nanoparticle-based drug delivery system that exhibits promising results and overcomes these problems. This study was conducted [...] Read more.
Microbial infections present a challenging arena to the modern world. Traditional antibiotics are now familiar to microbes. To counter this microbial familiarity, a novel approach is a nanoparticle-based drug delivery system that exhibits promising results and overcomes these problems. This study was conducted to explore the efficacy of silver nanoparticles (AgNPs) by utilizing stem bark extract of Sterculia diversifolia followed by physicochemical characterization including ultraviolet-visible spectrophotometry (UV-Vis), X-ray diffractometer (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Fourier-transform infrared spectroscopy. The UV-Vis characteristic spectral peak was recorded at 430 nm. XRD confirmed the crystalline structure of AgNPs, while FTIR confirmed phytochemicals in their capping, stabilization, and synthesis of AgNPs. SEM devised the particle size range of 100 nm at 30,000× magnification. TEM showed nanoparticles morphology, which is spherical in nature, while obtained nanoparticles were 100 nm in size. The antibacterial activity of synthesized NPs showed significant action against S. aureus and P. aeruginosa. Similarly, crude extract and n-hexane fraction showed maximum zone of inhibition. Promising results suggest that stem bark extract AgNPs of Sterculia diversifolia can be studied further for microbial mechanisms as well as formulation-based studies. Full article
(This article belongs to the Topic Preparation and Antibacterial Properties of Metal Nanoparticles)
(This article belongs to the Section Inorganic Crystalline Materials)
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20 pages, 5973 KiB  
Article
Aspergillus terreus-Mediated Selenium Nanoparticles and Their Antimicrobial and Photocatalytic Activities
by Ebrahim Saied, Alsayed E. Mekky, Abdulaziz A. Al-Askar, Abdelrahman F. Hagag, Abdullah A. El-bana, Mohamed Ashraf, Abdelrahman Walid, Taha Nour, Mahmoud M. Fawzi, Amr A. Arishi and Amr H. Hashem
Crystals 2023, 13(3), 450; https://doi.org/10.3390/cryst13030450 - 4 Mar 2023
Cited by 20 | Viewed by 3248
Abstract
Selenium (Se) is a nutritional component necessary for animal and plant development and reproduction. Selenium nanoparticles (SeNPs) have a high absorption rate during routine supplementation. In the current study, a cell-free extract of Aspergillus terreus was used as a reducing and stabilizing agent in [...] Read more.
Selenium (Se) is a nutritional component necessary for animal and plant development and reproduction. Selenium nanoparticles (SeNPs) have a high absorption rate during routine supplementation. In the current study, a cell-free extract of Aspergillus terreus was used as a reducing and stabilizing agent in the synthesis of SeNPs using a green and eco-friendly method. The mycosynthesized SeNPs were characterized by UV-visible spectrophotometry, Fourier transform infrared spectroscopy, X-ray diffraction spectroscopy, dynamic light scattering, transmission electron microscopy, and scanning electron microscopy. The results of the characterization process showed that the mycosynthesized SeNPs had spherical shapes and sizes less than 100 nm. Results showed that mycosynthesized SeNPs exhibited promising antibacterial activity against both Gram-positive and Gram-negative bacteria where inhibition zones were 14, 20, 16, and 13 mm toward S. haemolyticus, S. aureus, E. coli, and K. pneumoniae, respectively. However, it had weak antifungal activity against C. albicans, where the inhibition zone was 12 mm. The efficacy of mycosynthesized SeNPs for the decolorization of malachite green dye was investigated. Results illustrated that SeNPs exhibited rapid biodegradation of malachite green dye, reaching up to 89% after 240 min. In conclusion, SeNPs were successfully biosynthesized using A. terreus and demonstrated both antimicrobial and photocatalytic activities. Full article
(This article belongs to the Topic Preparation and Antibacterial Properties of Metal Nanoparticles)
(This article belongs to the Section Inorganic Crystalline Materials)
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11 pages, 905 KiB  
Article
Green Synthesis of Silver Nanoparticles Using Rhazya stricta Decne Extracts and Their Anti-Microbial and Anti-Oxidant Activities
by Haji Rahman, Abdur Rauf, Shahid Ali Khan, Zubair Ahmad, Abdulrahman Alshammari, Metab Alharbi, Amir Alam and Hafiz Ansar Rasul Suleria
Crystals 2023, 13(3), 398; https://doi.org/10.3390/cryst13030398 - 25 Feb 2023
Cited by 18 | Viewed by 2771
Abstract
The present study shows the synthesis of silver nanoparticles (Ag NPs) using a methanolic and aqueous extract of R. stricta. UV–visible spectroscopy, energy-dispersive X-ray diffraction (EDX), field emission scanning electron microscopy (FESEM), and Fourier transform infrared spectroscopy (FTIR) techniques were used to [...] Read more.
The present study shows the synthesis of silver nanoparticles (Ag NPs) using a methanolic and aqueous extract of R. stricta. UV–visible spectroscopy, energy-dispersive X-ray diffraction (EDX), field emission scanning electron microscopy (FESEM), and Fourier transform infrared spectroscopy (FTIR) techniques were used to further characterize the Ag NPs. UV–visible spectra give surface Plasmon resonance (SPR) at 490–560 nm for Ag NPs. The existence of various functional groups existing in biomolecules capping the nanoparticles is indicated by the FTIR spectrum. The average size of Ag NPs is 20–35 nm, while the shape is spherical, as confirmed by FESEM. The plant extract and Ag NPs were evaluated against their antioxidant, antibacterial (Staphylococcus aureus, E. coli, and Salmonella typhi), and antifungal activities (Trichophyton longifusis, Candida albican, and Fusarium solani), where the Ag NPs exhibited superior activity versus the plant extract. The inhibitory effect of NPs against the tested strain was more effective as compared to the crude extract of R. stricta. Full article
(This article belongs to the Topic Preparation and Antibacterial Properties of Metal Nanoparticles)
(This article belongs to the Section Inorganic Crystalline Materials)
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14 pages, 1562 KiB  
Article
Antimicrobial, Antiasthmatic and Cytotoxic Activities of Silver Nanoparticles Synthesized by Green Method Using Zingiber officinale Extract
by Murad A. Mubaraki, Kashif Mustafa, Fozia Fozia, Madeeha Aslam, Ijaz Ahmad and Nisar Ahmad
Crystals 2023, 13(2), 333; https://doi.org/10.3390/cryst13020333 - 16 Feb 2023
Cited by 3 | Viewed by 1840
Abstract
In this study, effective and environmentally friendly methods were used to achieve the synthesis of silver nanoparticles (Ag NPs) by an aqueous plant extract. The Ag NPs were synthesized via Zingiber officinale plant extract that acted as a reducing and stabilizing agent. Various [...] Read more.
In this study, effective and environmentally friendly methods were used to achieve the synthesis of silver nanoparticles (Ag NPs) by an aqueous plant extract. The Ag NPs were synthesized via Zingiber officinale plant extract that acted as a reducing and stabilizing agent. Various techniques, including UV-Visible spectroscopy (UV-Vis), X-ray diffraction pattern (XRD), Fourier transform infrared spectroscopy (FT-IR), and scanning electron microscopy (SEM) were used. The plant extract treated with silver nitrate solution at room temperature (27 ± 20) resulted in the successful synthesis of the Ag NPs, that were confirmed by UV-Vis spectroscopy. The crystalline morphology and size of the nanoparticles were calculated using Scherrer equation, that specify a face-centered cubic (fcc) crystalline structure with size ranges as 16 nm. The spherical geometry of Ag NPs was confirmed from scanning electron microscopy. FT-IR study validates the existence of several functional groups of active biomolecules such as -OH, C-O, C=C, C-O-C, and N-H that act as a reducing and capping agent for the synthesis of Ag NPs and were found in the extract. The synthesized Ag NPs were used to evaluated antimicrobial activity against different bacterial and fungal strains. The Zingiber officinale-Ag NPs exhibited maximum zone of inhibition against Staphylococcus aureus bacterial strain which were 17.8 ± 0.03 mm, and Fusarium graminium fungal strain showed 11.0 ± 0.01 mm at 80 µg/mL concentrations, respectively. Furthermore, the Ag NPs were considered to be a significant anti-asthma agent that decreased the white blood cells (WBC), eosinophils (EOS) in blood level, and wet/dry (W/D) weight proportion of the lung at 24 µg/g/day. The cytotoxicity of synthesized nanoparticles shows that the concentration under 90 µg/mL were biologically compatible. Full article
(This article belongs to the Topic Preparation and Antibacterial Properties of Metal Nanoparticles)
(This article belongs to the Section Inorganic Crystalline Materials)
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24 pages, 1785 KiB  
Review
A Review of Bimetallic and Monometallic Nanoparticle Synthesis via Laser Ablation in Liquid
by Anesu Nyabadza, Mercedes Vazquez and Dermot Brabazon
Crystals 2023, 13(2), 253; https://doi.org/10.3390/cryst13020253 - 1 Feb 2023
Cited by 36 | Viewed by 5935
Abstract
Pulsed laser ablation in liquid (PLAL) is a physical and top-down approach used to fabricate nanoparticles (NPs). Herein, the research methods and current trends in PLAL literature are reviewed, including the recent uses of PLAL for fabricating bimetallic nanoparticles (BNPs) and composites. BNPs [...] Read more.
Pulsed laser ablation in liquid (PLAL) is a physical and top-down approach used to fabricate nanoparticles (NPs). Herein, the research methods and current trends in PLAL literature are reviewed, including the recent uses of PLAL for fabricating bimetallic nanoparticles (BNPs) and composites. BNPs have gained attention owing to their advanced physicochemical properties over monometallic NPs. PLAL involves the irradiation of a solid target (usually a rod, plate, or thin film) under a liquid medium. The liquid collects the ejected NPs resulting from the laser processing, which produces a colloid that can be in various applications, including plasmon sensing, energy harvesting, and drug delivery. The most used fabrication techniques, including the use of microorganisms, do not have precise NP size control and require the separation of the microorganisms from the produced NPs. PLAL is quicker at producing NPs than bottom-up methods. The drawbacks of PLAL include the need to find the required laser processing parameters, which requires extensive experimentation, and the complex and non-linear relationships between the inputs and the outputs (e.g., NP size). Full article
(This article belongs to the Topic Preparation and Antibacterial Properties of Metal Nanoparticles)
(This article belongs to the Section Inorganic Crystalline Materials)
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13 pages, 2442 KiB  
Article
Mycosynthesis, Characterization of Zinc Oxide Nanoparticles, and Its Assessment in Various Biological Activities
by Asif Kamal, Malka Saba, Khetab Ullah, Saeedah Musaed Almutairi, Bandar M. AlMunqedhi and Mohamed Ragab abdelGawwad
Crystals 2023, 13(2), 171; https://doi.org/10.3390/cryst13020171 - 18 Jan 2023
Cited by 17 | Viewed by 3277
Abstract
In recent years, nanotechnology has become one of the emerging fields of nanoparticle synthesis using biological processes. The use of mushroom extract is one of the most important methods for biological synthesis due to the presence of abundant biologically active compounds. In this [...] Read more.
In recent years, nanotechnology has become one of the emerging fields of nanoparticle synthesis using biological processes. The use of mushroom extract is one of the most important methods for biological synthesis due to the presence of abundant biologically active compounds. In this study, Zinc Oxide nanoparticles (ZnO NPs) were synthesized using Daedalea sp. mushroom extract. The nanoparticles had an average size of 14.58 nm and irregular morphology, which shows its prominent character. Various analytical techniques including FTIR, X-ray diffraction, EDX, and UV-Vis spectrum showed a broad absorption between 350 and 380 nm, which indicates the synthesis of ZnO NPs. The characterized NPs were exploited for a wide range of biomedical applications including biocompatibility, antifungal, antileishmanial, and antibacterial studies. The ZnO nanoparticles showed a strong antibacterial effect against gram-positive (Klesbsilla pneumonia and Staphylococcus aureus) and gram-negative (Eschericia coli and Pseudomonas aeruginosa) bacteria. Furthermore, the ZnO nanoparticles also showed a high antifungal effect against Aspergillus niger fungus. Full article
(This article belongs to the Topic Preparation and Antibacterial Properties of Metal Nanoparticles)
(This article belongs to the Section Inorganic Crystalline Materials)
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16 pages, 4187 KiB  
Article
Effects of Hydrothermal Reaction Time on the Structure and Optical Properties of ZnO/Graphene Oxide Nanocomposites
by Tran Van Khai, Le Ngoc Long, Nguyen Hoang Thien Khoi and Nguyen Hoc Thang
Crystals 2022, 12(12), 1825; https://doi.org/10.3390/cryst12121825 - 14 Dec 2022
Cited by 7 | Viewed by 2732
Abstract
In this research, ZnO/GO nanocomposites were successfully synthesized by a simple hydrothermal method using graphene oxide (GO) and zinc acetate dihydrate (Zn(CH3COO)2.2H2O) as the reactants. The effect of the hydrothermal reaction time on the structure and optical [...] Read more.
In this research, ZnO/GO nanocomposites were successfully synthesized by a simple hydrothermal method using graphene oxide (GO) and zinc acetate dihydrate (Zn(CH3COO)2.2H2O) as the reactants. The effect of the hydrothermal reaction time on the structure and optical property of the ZnO/GO was systematically investigated. The structure, morphology and chemical composition of the samples were measured by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDS) and Raman and Fourier transform infrared (FTIR) spectroscopy, while the optical properties were measured using photoluminescence spectroscopy. The synthesized products consisted of large quantities of one-dimensional (1D) ZnO nanorods (NRs), which were dispersed uniformly on the GO surface. The XRD and Raman results reveal that the ZnO NRs in the fabricated samples had a hexagonal wurtzite structure with high crystalline quality. The FESEM and TEM images reveal that ZnO NRs with an average diameter in the range of ~85–270 nm and length in the range of ~0.3–6 μm were covered with GO sheets. Additionally, it was found that the crystallographic orientation of ZnO NRs was dependent not only on the hydrothermal reaction time but also on the presence of GO in the nanocomposites. However, the addition of GO did not affect the stoichiometric ratio and the crystal structure of ZnO NRs. The room-temperature PL results indicated that, compared to those of pure ZnO, the luminescence of the GO/ZnO nanocomposites was suppressed and shifted towards a higher wavelength (red shift), which was attributed to the incorporation of ZnO NRs within the GO matrix and the formation of a C-O-Zn chemical bond in the nanocomposites. The hydrothermal technique is considered one of the best routes due to its low cost, high growth rates, low-temperature synthesis, controllable crystallographic orientation, particle size, as well as morphology. Full article
(This article belongs to the Topic Preparation and Antibacterial Properties of Metal Nanoparticles)
(This article belongs to the Section Inorganic Crystalline Materials)
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21 pages, 2388 KiB  
Review
An Overview of Iron Oxide (Fe3O4) Nanoparticles: From Synthetic Strategies, Characterization to Antibacterial and Anticancer Applications
by Muhammad Rukhsar, Zubair Ahmad, Abdur Rauf, Hassan Zeb, Mujeeb Ur-Rehman and Hassan A. Hemeg
Crystals 2022, 12(12), 1809; https://doi.org/10.3390/cryst12121809 - 12 Dec 2022
Cited by 12 | Viewed by 4615
Abstract
Magnetic nanoparticles have been discovered to be promising materials for various biomedical applications; for example, they have been used for cancer detection, screening, and chemotherapy studies during the last few decades. Likewise, magnetic nanoparticles have significant antibacterial properties, and similarly, they can be [...] Read more.
Magnetic nanoparticles have been discovered to be promising materials for various biomedical applications; for example, they have been used for cancer detection, screening, and chemotherapy studies during the last few decades. Likewise, magnetic nanoparticles have significant antibacterial properties, and similarly, they can be applied for magnetic resonance imaging purposes. These sensors are meant to detect certain biomarkers, which are substances that can be linked to the beginning or progression of cancer both during and after therapy. Magnetic nanoparticles have several unique properties that are being employed widely in cancer therapy as drug delivery agents to precisely target the targeted spot using an external magnetic field in vivo. Magnetic resonance imaging can also be used in conjunction with antineoplastic drug treatment personalized to the individual. We have presented an overview of the different applications of magnetic nanoparticles as well as current breakthroughs in their development as antibacterial and cancer therapies in this review. In addition, the cancer targeting, possible toxicity, and degradability of these nanomaterials are briefly discussed. Full article
(This article belongs to the Topic Preparation and Antibacterial Properties of Metal Nanoparticles)
(This article belongs to the Section Inorganic Crystalline Materials)
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9 pages, 1929 KiB  
Article
Phytogenic Fabrication of Copper Oxide Nanoparticles for Antibacterial and Antioxidant Screening: Physico-Chemical Study
by Fazal Ur Rehman, Rashid Mahmood, Sirajul Haq, Pervaiz Ahmad, Salah Ud Din, Mayeen Uddin Khandaker, Abubakr M. Idris and Ivar Zekker
Crystals 2022, 12(12), 1796; https://doi.org/10.3390/cryst12121796 - 9 Dec 2022
Cited by 4 | Viewed by 1639
Abstract
Bergenia ciliata (B. ciliate) leaf extract was used as a capping and stabilizing agent to synthesize copper oxide nanoparticles (CuO NPs). The selection of B. ciliate is purely based on its rich phytochemical composition and less utilization in green chemistry. The [...] Read more.
Bergenia ciliata (B. ciliate) leaf extract was used as a capping and stabilizing agent to synthesize copper oxide nanoparticles (CuO NPs). The selection of B. ciliate is purely based on its rich phytochemical composition and less utilization in green chemistry. The X-ray diffraction (XRD) analysis showed that the CuO NPs were found to be highly crystalline, while the irregular morphology and other structural properties were investigated by scanning electron microscopy (SEM) and transmission electron microscopy (TEM), and the average particle size was found to be 50.05 nm. Energy dispersive X-ray (EDX) spectroscopy was used to determine the percentage composition and purity, whereas Fourier transform infrared (FTIR) spectroscopy was utilized to examine the surface functional groups. CuO NPs were tested for their antibacterial properties against Gram-positive and Gram-negative bacteria, and the activity was found to increase with an increasing concentration of CuO NPs in the wells. The dose-dependent antioxidant potential is slightly higher than ascorbic acid. Full article
(This article belongs to the Topic Preparation and Antibacterial Properties of Metal Nanoparticles)
(This article belongs to the Section Inorganic Crystalline Materials)
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