Liver Diseases: From Pathogenesis to Modern Management

Dear Colleagues,

This Topic aims to provide a comprehensive and forward-looking overview of liver diseases, spanning fundamental mechanisms of pathogenesis to contemporary and emerging therapeutic strategies. We invite high-quality original research, systematic reviews, and expert perspectives that advance understanding of molecular, genetic, metabolic, immune, and environmental drivers of liver injury and disease progression. Topics of interest include, but are not limited to, viral hepatitis, metabolic dysfunction- associated steatotic liver disease (MASLD), cirrhosis, portal hypertension, hepatocellular carcinoma, cholangiopathies, autoimmune liver disorders, and liver transplantation. Emphasis will be placed on translational research, precision medicine, biomarkers, innovative imaging, interventional hepatology, surgical and transplant advances, and novel pharmacologic and regenerative therapies. By integrating basic science discoveries with clinical innovation, this Topic seeks to bridge bench-to-bedside gaps, highlight evolving standards of care, and shape future directions in hepatology. Our goal is to create a high-impact, multidisciplinary resource for clinicians, researchers, and policymakers committed to improving outcomes in liver disease.

Dr. Dimitrios Moris
Dr. Georgia Sofia Karachaliou
Topic Editors