Findings, Insights and Perspectives on Central Nervous System Tumors

Dear Colleagues,

Central nervous system (CNS) cancers are neoplastic diseases stemming from the brain and its surrounding structures, with increasing incidence, and high mortality and morbidity rates worldwide. They are characterized by their aggressive nature, marked heterogeneity and adaptation to chemoresistance, leading to a poor prognosis and clinical outcome. With the ongoing advances in research, the medical field is trying to abandon the “one size fits all” philosophy and adopt a personalized medicine approach, developing novel drug and formulation strategies that can target specific disease biomarkers. The aim of this topic is to provide a forum for researchers and clinicians to share their latest findings, insights, and perspectives on CNS tumors. We welcome original research and review articles on a range of topics related to CNS neoplasms, including, but not limited to, the following: (1) the molecular and cellular mechanisms of cancer initiation, progression, and resistance; (2) advances in diagnosis and treatment; (3) novel drug delivery strategies for cancer therapy; (4) new diagnostic and prognostic biomarkers; (5) innovative 3D microphysiological models for cancer and tumor microenvironment research; and (6) the synergy of machine learning in designing more efficient therapies.

Dr. João Basso
Dr. Carla Vitorino
Dr. Rui Vitorino
Dr. Ana Fortuna
Topic Editors