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3 Results Found

  • Article
  • Open Access
15 Citations
4,787 Views
16 Pages

Exploring Obscurin and SPEG Kinase Biology

  • Jennifer R. Fleming,
  • Alankrita Rani,
  • Jamie Kraft,
  • Sanja Zenker,
  • Emma Börgeson and
  • Stephan Lange

2 March 2021

Three members of the obscurin protein family that contain tandem kinase domains with important signaling functions for cardiac and striated muscles are the giant protein obscurin, its obscurin-associated kinase splice isoform, and the striated muscle...

(This article belongs to the Section Cardiology)
  • Article
  • Open Access
11 Citations
6,506 Views
15 Pages

On the Rate of Synthesis of Individual Proteins within and between Different Striated Muscles of the Rat

  • Stuart Hesketh,
  • Kanchana Srisawat,
  • Hazel Sutherland,
  • Jonathan Jarvis and
  • Jatin Burniston

The turnover of muscle protein is responsive to different (patho)-physiological conditions but little is known about the rate of synthesis at the level of individual proteins or whether this varies between different muscles. We investigated the synth...

(This article belongs to the Special Issue Striated Muscle Proteomics)
  • Communication
  • Open Access
3 Citations
3,083 Views
9 Pages

Dilated-Left Ventricular Non-Compaction Cardiomyopathy in a Pediatric Case with SPEG Compound Heterozygous Variants

  • Hager Jaouadi,
  • Fedoua El Louali,
  • Chloé Wanert,
  • Aline Cano,
  • Caroline Ovaert and
  • Stéphane Zaffran

Left Ventricular Non-Compaction (LVNC) is defined by the triad prominent myocardial trabecular meshwork, thin compacted layer, and deep intertrabecular recesses. LVNC associated with dilation is characterized by the coexistence of left ventricular di...

(This article belongs to the Special Issue Calcium Handling)