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3 Results Found

  • Article
  • Open Access
25 Citations
7,080 Views
19 Pages

Optimization of Ursolic Acid Extraction in Oil from Annurca Apple to Obtain Oleolytes with Potential Cosmeceutical Application

  • Maria Maisto,
  • Vincenzo Piccolo,
  • Ettore Novellino,
  • Elisabetta Schiano and ,
  • Fortuna Iannuzzo,
  • Roberto Ciampaglia,
  • Vincenzo Summa and
  • Gian Carlo Tenore
  • + 3 authors+ 0 author

18 January 2023

Ursolic acid (UA) is a plant-derived molecule with relevant anti-aging activity, which makes this molecule a potential functional active ingredient in cosmetic formulations. The main objectives of this study were to optimize the UA extraction process...

(This article belongs to the Special Issue Green Extraction of Natural Products (GENP 2022))
  • Article
  • Open Access
7 Citations
4,952 Views
15 Pages

Therapeutic Effect of an Ursolic Acid-Based Nutraceutical on Neuronal Regeneration after Sciatic Nerve Injury

  • Fortuna Iannuzzo,
  • Annunziata Gaetana Cicatiello,
  • Serena Sagliocchi,
  • Elisabetta Schiano and ,
  • Annarita Nappi,
  • Caterina Miro,
  • Mariano Stornaiuolo,
  • Adriano Mollica,
  • Gian Carlo Tenore and
  • Ettore Novellino
  • + 6 authors+ 1 author

Peripheral nerve injuries lead to severe functional impairments and long recovery times, with limited effectiveness and accessibility of current treatments. This has increased interest in natural bioactive compounds, such as ursolic acid (UA). Our st...

(This article belongs to the Special Issue Advances in Natural Active Products Derived from Foods: Antioxidant, Antinociceptive and Anti-inflammatory Activities)
  • Communication
  • Open Access
3,538 Views
11 Pages

Ursolic Acid-Based Nutraceutical Mitigates Muscle Atrophy and Improves Exercise Performance in Mouse Model of Peripheral Neuropathy

  • Caterina Miro,
  • Fortuna Iannuzzo,
  • Lucia Acampora,
  • Annunziata Gaetana Cicatiello and ,
  • Serena Sagliocchi,
  • Elisabetta Schiano,
  • Annarita Nappi,
  • Federica Restolfer,
  • Mariano Stornaiuolo and
  • Ettore Novellino
  • + 7 authors+ 2 authors

Peripheral nerve injuries, caused by trauma or iatrogenic damage, often lead to permanent disabilities with limited effectiveness of current therapeutic treatments. This has driven the growing interest toward natural bioactive molecules, including ur...

(This article belongs to the Section Bioactives and Nutraceuticals)