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12 Results Found

  • Article
  • Open Access
8 Citations
3,794 Views
13 Pages

Prevalence of Diarrhoeagenic Escherichia coli among Children Aged between 0–36 Months in Peri-Urban Areas of Lusaka

  • Kapambwe Mwape,
  • Samuel Bosomprah,
  • Kennedy Chibesa,
  • Suwilanji Silwamba,
  • Charlie Chaluma Luchen,
  • Nsofwa Sukwa,
  • Cynthia Mubanga,
  • Bernard Phiri,
  • Mwelwa Chibuye and
  • Roma Chilengi
  • + 7 authors

Diarrhoea is a major contributor to childhood morbidity and mortality in developing countries, with diarrhoeagenic Escherichia coli being among the top aetiological agents. We sought to investigate the burden and describe the diarrhoeagenic E. coli p...

  • Feature Paper
  • Article
  • Open Access
10 Citations
3,502 Views
12 Pages

Behaviour of Non-O157 STEC and Atypical EPEC during the Manufacturing and Ripening of Raw Milk Cheese

  • Edson A. Rios,
  • Juliana Ramos-Pereira,
  • Jesús A. Santos,
  • Teresa M. López-Díaz,
  • Andrés Otero and
  • Jose M. Rodríguez-Calleja

1 September 2020

This study was carried out to assess the survival of Shiga toxin-producing E. coli (STEC) and atypical enteropathogenic Escherichia coli (aEPEC) during the traditional manufacturing and ripening of Spanish hard cheese from raw cow’s milk. Milk...

  • Article
  • Open Access
9 Citations
5,298 Views
18 Pages

Mixed Aetiology of Diarrhoea in Infants Attending Clinics in the North-West Province of South Africa: Potential for Sub-Optimal Treatment

  • Martina O. Chukwu,
  • Akebe Luther King Abia,
  • Eunice Ubomba-Jaswa,
  • John Barr Dewar and
  • C.L. Obi

Routine diagnostic methods for the aetiologic agents of diarrhoea in most developing countries are usually not sensitive enough, leading to under-diagnosis. Thus, this study investigated possible mixed diarrhoeal aetiology by using cultures and real-...

  • Article
  • Open Access
1 Citations
2,133 Views
14 Pages

Application of a Novel Proteomic Microarray Reveals High Exposure to Diarrhoeagenic Escherichia coli among Children in Zambia Participating in a Phase I Clinical Trial

  • Kapambwe Mwape,
  • Cynthia Mubanga,
  • Obvious Nchimunya Chilyabanyama,
  • Kennedy Chibesa,
  • Caroline Cleopatra Chisenga,
  • Suwilanji Silwamba,
  • Arlo Randall,
  • Xiaowu Liang,
  • Tobias George Barnard and
  • Roma Chilengi
  • + 1 author

Diarrhoeagenic E. coli (DEC) significantly contributes to the burden of diarrhoea among children. Currently, there is no approved vaccine against DEC, but several vaccines against the enterotoxigenic E. coli (ETEC) pathotype are in advanced clinical...

  • Article
  • Open Access
3 Citations
1,564 Views
9 Pages

Global Dynamics of Gastrointestinal Colonisations and Antimicrobial Resistance: Insights from International Travellers to Low- and Middle-Income Countries

  • Laura Seijas-Pereda,
  • David Carmena,
  • Carlos Rescalvo-Casas,
  • Marcos Hernando-Gozalo,
  • Laura Prieto-Pérez,
  • Juan Cuadros-González and
  • Ramón Pérez-Tanoira

Gastrointestinal microorganism resistance and dissemination are increasing, partly due to international travel. This study investigated gastrointestinal colonisations and the acquisition of antimicrobial resistance (AMR) genes among international tra...

  • Article
  • Open Access
9 Citations
4,041 Views
15 Pages

Winning the War against Multi-Drug Resistant Diarrhoeagenic Bacteria

  • Chizoba Mercy Enemchukwu,
  • Angus Nnamdi Oli,
  • Ebere Innocent Okoye,
  • Nonye Treasure Ujam,
  • Emmanuel O. Osazuwa,
  • George Ogonna Emechebe,
  • Kenneth Nchekwube Okeke,
  • Christian Chukwuemeka Ifezulike,
  • Obiora Shedrack Ejiofor and
  • Jude Nnaemeka Okoyeh

Drug-resistant-diarrhoeagenic bacteria are currently emerging healthcare challenge. This study investigated the effects of Vernonia amygdalina, Garcinia kola, tetracycline and metronidazole combinations on such bacteria. Agar well diffusion method wa...

  • Article
  • Open Access
4 Citations
4,934 Views
12 Pages

Bacterial Contamination of Children’s Toys in Rural Day Care Centres and Households in South Africa

  • Solanka Ellen Ledwaba,
  • Piet Becker,
  • Afsatou Traore-Hoffman and
  • Natasha Potgieter

Background: Young children exhibit a high susceptibility to several diarrhoea-causing bacterial microorganisms. In this study, the prevalence of fecal contamination on children’s toys was determined using total coliform and E. coli as bacterial...

  • Article
  • Open Access
963 Views
20 Pages

Consumption of contaminated drinking water is known to cause waterborne diseases such as diarrhoea, dysentery, typhoid, and hepatitis. This study applied whole-genome sequencing (WGS) to detect, identify, compare, and profile diarrhoeagenic pathogens...

  • Article
  • Open Access
1,604 Views
11 Pages

Antibiotic Resistance Profiles of Diarrhoeagenic Enterobacterales in Bioko Island, Equatorial Guinea

  • Úrsula-Eva Eñeso Efuá,
  • Silvia Herrera-León,
  • Fátima Patabobe,
  • Pascual Erasmo Owono and
  • Agustín Benito

Acute diarrhoeal disease caused by antibiotic-resistant diarrhoeagenic bacteria is a significant global public health issue, particularly in low- and middle-income countries. This study provides the first molecular characterisation of antimicrobial r...

  • Article
  • Open Access
5 Citations
3,054 Views
18 Pages

Specific Proteomic Identification of Collagen-Binding Proteins in Escherichia coli O157:H7: Characterisation of OmpA as a Potent Vaccine Antigen

  • Ricardo Monteiro,
  • Ingrid Chafsey,
  • Nelly Caccia,
  • Valentin Ageorges,
  • Sabine Leroy,
  • Didier Viala,
  • Michel Hébraud,
  • Valérie Livrelli,
  • Mariagrazia Pizza and
  • Mickaël Desvaux
  • + 1 author

15 June 2023

Escherichia coli is a versatile commensal species of the animal gut that can also be a pathogen able to cause intestinal and extraintestinal infections. The plasticity of its genome has led to the evolution of pathogenic strains, which represent a th...

  • Article
  • Open Access
17 Citations
5,209 Views
15 Pages

Survey of Zoonotic Diarrheagenic Protist and Hepatitis E Virus in Wild Boar (Sus scrofa) of Portugal

  • Sérgio Santos-Silva,
  • Danny Franciele da Silva Dias Moraes,
  • Pedro López-López,
  • Josman D. Palmeira,
  • Rita T. Torres,
  • Maria São José Nascimento,
  • Alejandro Dashti,
  • David Carmena,
  • Antonio Rivero-Juarez and
  • João R. Mesquita

12 January 2023

Enteropathogenic parasites and viruses have been frequently reported in swine and can infect a wide range of mammals, including humans. Among the wide variety of parasites infecting swine, diarrhoeagenic protists are among those that cause significan...

  • Article
  • Open Access
24 Citations
4,030 Views
13 Pages

This study was undertaken to determine the virulence and antibiotic resistance profiles of diarrhoeagenic Escherichia coli (DEC) in environmental waters of Johannesburg, South Africa. Samples were collected and cultured on selective media. An 11-plex...