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6 Results Found

  • Article
  • Open Access
3 Citations
3,113 Views
17 Pages

Synthesis of Fluorogenic Arylureas and Amides and Their Interaction with Amines: A Competition between Turn-on Fluorescence and Organic Radicals on the Way to a Smart Label for Fish Freshness

  • Javier García-Tojal,
  • José V. Cuevas,
  • María-Josefa Rojo,
  • Borja Díaz de Greñu and ,
  • Carla Hernando-Muñoz,
  • José García-Calvo,
  • Mateo M. Salgado and
  • Tomás Torroba
  • + 3 authors+ 0 author

We describe the synthesis of fluorogenic arylureas and amides and their interaction with primary or secondary amines under air and light in organic-aqueous mixtures to give rise to a new class of persistent organic radicals, described on the basis of...

(This article belongs to the Special Issue New Synthetic Methods for Organic Compounds)
  • Review
  • Open Access
77 Citations
9,029 Views
17 Pages

The Different Facets of Triclocarban: A Review

  • Domenico Iacopetta,
  • Alessia Catalano,
  • Jessica Ceramella,
  • Carmela Saturnino and ,
  • Lara Salvagno,
  • Ileana Ielo,
  • Dario Drommi,
  • Elisabetta Scali,
  • Maria Rosaria Plutino and
  • Maria Stefania Sinicropi
  • + 6 authors+ 1 author

In the late 1930s and early 1940s, it was discovered that the substitution on aromatic rings of hydrogen atoms with chlorine yielded a novel chemistry of antimicrobials. However, within a few years, many of these compounds and formulations showed adv...

(This article belongs to the Special Issue Materials for Healthcare)
  • Review
  • Open Access
53 Citations
5,791 Views
25 Pages

Diarylureas: Repositioning from Antitumor to Antimicrobials or Multi-Target Agents against New Pandemics

  • Alessia Catalano,
  • Domenico Iacopetta,
  • Michele Pellegrino,
  • Stefano Aquaro and ,
  • Carlo Franchini and
  • Maria Stefania Sinicropi
  • + 1 author+ 0 author

Antimicrobials have allowed medical advancements over several decades. However, the continuous emergence of antimicrobial resistance restricts efficacy in treating infectious diseases. In this context, the drug repositioning of already known biologic...

  • Review
  • Open Access
12 Citations
4,818 Views
14 Pages

Thidiazuron: New Trends and Future Perspectives to Fight Xylella fastidiosa in Olive Trees

  • Alessia Catalano,
  • Jessica Ceramella,
  • Domenico Iacopetta,
  • Annaluisa Mariconda and ,
  • Elisabetta Scali,
  • Maria Grazia Bonomo,
  • Carmela Saturnino,
  • Pasquale Longo,
  • Stefano Aquaro and
  • Maria Stefania Sinicropi
  • + 5 authors+ 0 author

These days, most of our attention has been focused on the COVID-19 pandemic, and we have often neglected what is happening in the environment. For instance, the bacterium Xylella fastidiosa re-emerged as a plant pathogen of global importance in 2013...

(This article belongs to the Special Issue Searching for Small Molecules as Antimicrobials)
  • Article
  • Open Access
1,442 Views
28 Pages

Design, Synthesis, and Structure–Activity Relationships of Substituted Phenyl Cyclobutylureas as Potential Modulators of Inflammatory Responses

  • Atziri Corin Chavez Alvarez,
  • Antoine Carpentier,
  • Ahmed Sahli,
  • Martin Perreault and ,
  • Aichatou Diallo Ngon and
  • Emmanuel Moreau
  • + 1 author+ 0 author

25 February 2026

Background/Objectives: Chronic inflammation underlies many immune-mediated conditions, yet current anti-inflammatory therapies are often limited by incomplete efficacy or safety concerns. Small molecules inspired by soluble epoxide hydrolase (sEH) in...

(This article belongs to the Section Medicinal Chemistry)
  • Article
  • Open Access
11 Citations
4,108 Views
18 Pages

Structural and Rheological Properties of Nonedible Vegetable Oil-Based Resin

  • Nurul Huda Mudri,
  • Luqman Chuah Abdullah,
  • Min Min Aung,
  • Dayang Radiah Awang Biak and
  • Rida Tajau

28 July 2021

Jatropha oil-based polyol (JOL) was prepared from crude Jatropha oil via an epoxidation and hydroxylation reaction. During the isocyanation step, two different types of diisocyanates; 2,4-toluene diisocyanate (2,4-TDI) and isophorone diisocyanate (IP...

(This article belongs to the Special Issue Advanced Bio-Based Polymers and Nanocomposites)