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  • Abstract
  • Open Access
1,605 Views
1 Page

Revolution in Evolution of Human “Anellome”

  • Joanna Kaczorowska,
  • Mila Sparreboom,
  • Martin Deijs,
  • Maarten F. Jebbink and
  • Lia van der Hoek

Torque teno viruses (TTVs), the most well-known members of the family Anelloviridae, are not associated with any disease. They are one of the most abundant and divergent entities in the viral world; however, the cause of their variability is not curr...

(This article belongs to the Proceedings of Viruses 2020—Novel Concepts in Virology)
  • Article
  • Open Access
6 Citations
3,329 Views
14 Pages

The Impact of First-Time SARS-CoV-2 Infection on Human Anelloviruses

  • Anne L. Timmerman,
  • Lisanne Commandeur,
  • Martin Deijs,
  • Maarten G. J. M. Burggraaff,
  • A. H. Ayesha Lavell,
  • Karlijn van der Straten,
  • Khadija Tejjani,
  • Jacqueline van Rijswijk,
  • Marit J. van Gils and
  • Lia van der Hoek
  • + 2 authors

9 January 2024

Members of the Anelloviridae family dominate the blood virome, emerging early in life. The anellome, representing the variety of anelloviruses within an individual, stabilizes by adulthood. Despite their supposedly commensal nature, elevated anellovi...

(This article belongs to the Special Issue Advancing Research of Anelloviruses)
  • Review
  • Open Access
3 Citations
2,371 Views
28 Pages

Anelloviruses: From General Biology to Their Role as Biomarkers of Immune Competence in HIV Infection

  • Alina R. Nokhova,
  • Kirill A. Elfimov,
  • Alexander M. Shestopalov,
  • Natalya M. Gashnikova and
  • Olga G. Kurskaya

13 February 2026

Viruses of the family Anelloviridae represent a predominant component of the human virome across various anatomical sites, yet their clinical significance remains poorly understood. This review summarizes current data on the dynamics and functional i...

(This article belongs to the Section Human Virology and Viral Diseases)
  • Article
  • Open Access
5 Citations
2,278 Views
13 Pages

Expansion of Betatorquevirus and/or Gammatorquevirus in Patients with Severe Clinical Outcomes of the Liver Diseases

  • Xiaoan Zhang,
  • William D. Park,
  • Marijn Thijssen,
  • Yanjuan Xu,
  • Long Ping Victor Tse,
  • Mahmoud Reza Pourkarim,
  • Rajeev Aurora and
  • Xiaofeng Fan

27 July 2023

Anellovirus (AV) is a ubiquitous virus in the human population. Individuals can be infected with multiple AV genera and species to form a heterogeneous repertoire, termed the anellome. Using advanced methods, we examined the anellomes from 12 paired...

(This article belongs to the Section Human Virology and Viral Diseases)
  • Review
  • Open Access
3 Citations
2,007 Views
20 Pages

The Role of Xenobiotics and Anelloviruses in Colorectal Cancer: Mechanisms and Perspectives

  • Francisco Aguayo,
  • Julio C. Tapia,
  • Gloria M. Calaf,
  • Juan P. Muñoz,
  • Julio C. Osorio,
  • Matías Guzmán-Venegas,
  • Carolina Moreno-León,
  • Jorge Levican and
  • Cristian Andrade-Madrigal

Xenobiotics are non-natural chemical compounds to which the human population is exposed. Chronic exposure to certain xenobiotics is associated with various diseases, including cancer development. Anelloviruses (AVs), including Torque Teno Virus (TTV)...

(This article belongs to the Special Issue Viral Infections and Cancer: Recent Advances and Future Perspectives)
  • Editorial
  • Open Access
6 Citations
1,874 Views
3 Pages

The Emerging Tool of the Human Anellovirome

  • Daniele Focosi,
  • Pietro Giorgio Spezia and
  • Fabrizio Maggi

20 June 2024

The blood virome is dominated by the Anelloviridae family, which emerges early in life; the anellome, which represents the variety of anelloviruses within an individual, stabilizes by adulthood [...]

(This article belongs to the Special Issue Advancing Research of Anelloviruses)
  • Communication
  • Open Access
10 Citations
2,770 Views
6 Pages

19 July 2023

Anelloviruses are extremely prevalent in the human population and are considered to be commensal parts of the human virome. The best-known member in humans is the Torque teno virus. Recent metagenomic next-generation sequencing investigations have he...

(This article belongs to the Special Issue Advancing Research of Anelloviruses)