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12 Results Found

  • Article
  • Open Access
9 Citations
4,606 Views
19 Pages

10 December 2018

Non-observable board diversity is an important organizational strategy for improving the long-term growth and survivability of firms. The involvement of corporate sustainability (CS) in top management teams has led to effective boards. By using agenc...

  • Article
  • Open Access
941 Views
25 Pages

The PCAOB’s 2006 Tax Service Restrictions and Earnings Management

  • Matthew Notbohm,
  • Xiaoli Guo and
  • Adrian Valencia

In 2006, the PCAOB implemented new restrictions on the auditor provision of some tax and contingent fee services provided to issuer audit clients. These restrictions were implemented to reduce auditor conflicts of interest inherent when the auditor p...

  • Article
  • Open Access
7 Citations
4,992 Views
16 Pages

The informativeness of financial reports has been of a great importance to both investors and academics. Earnings are crucial for evaluating future prospects and determining company value, especially around milestone events such as initial public off...

  • Article
  • Open Access
2 Citations
3,693 Views
24 Pages

Theoretically, accounting earnings could be used to estimate the intrinsic value of equity. If accounting earnings could be predicted accurately, then, so could be the value of equity, thereby, creating much less risk in equity investment. However, e...

  • Review
  • Open Access
28 Citations
9,206 Views
24 Pages

Potential Relationship between Inadequate Response to DNA Damage and Development of Myelodysplastic Syndrome

  • Ting Zhou,
  • Peishuai Chen,
  • Jian Gu,
  • Alexander J. R. Bishop,
  • Linda M. Scott,
  • Paul Hasty and
  • Vivienne I. Rebel

5 January 2015

Hematopoietic stem cells (HSCs) are responsible for the continuous regeneration of all types of blood cells, including themselves. To ensure the functional and genomic integrity of blood tissue, a network of regulatory pathways tightly controls the p...

  • Review
  • Open Access
5 Citations
8,800 Views
12 Pages

22 August 2024

Comprehensive analyses of the molecular heterogeneity of acute myelogenous leukemia, AML, particularly when malignant cells retain normal karyotype, has significantly evolved. In 2022, significant revisions were introduced in the World Health Organiz...

  • Article
  • Open Access
4 Citations
3,564 Views
15 Pages

Infection-Associated Flares in Systemic Lupus Erythematosus

  • Giuseppe A. Ramirez,
  • Chiara Calabrese,
  • Marta Secci,
  • Luca Moroni,
  • Gabriele D. Gallina,
  • Giovanni Benanti,
  • Enrica P. Bozzolo,
  • Marco Matucci-Cerinic and
  • Lorenzo Dagna

26 October 2024

Systemic lupus erythematosus (SLE) is characterised by generalised immune dysfunction, including infection susceptibility. Infection-associated flares (IAFs) are common and might rapidly self-resolve, paralleling infection resolution, but their speci...

  • Article
  • Open Access
2 Citations
3,514 Views
30 Pages

On 15 December 2015, the Public Company Accounting Oversight Board (PCAOB) passed Rule 3211, requiring audit firms registered with PCAOB in the U.S. to disclose the audit engagement partner’s name in the Form AP, effective 31 January 2017. The regula...

  • Review
  • Open Access
1 Citations
2,774 Views
16 Pages

23 July 2025

Children and adolescents with type 1 diabetes (T1D) often experience abnormalities in bone health. Studies have consistently demonstrated that youth with T1D have lower bone mineral density (BMD) compared to their healthy peers. Additionally, childre...

  • Article
  • Open Access
26 Citations
4,370 Views
21 Pages

Inhibition of PGE2 in Subchondral Bone Attenuates Osteoarthritis

  • Qi Sun,
  • Yuanzhen Zhang,
  • Yilan Ding,
  • Wenqing Xie,
  • Hengzhen Li,
  • Shaohua Li,
  • Yusheng Li and
  • Ming Cai

5 September 2022

Aberrant subchondral bone architecture is a crucial driver of the pathological progression of osteoarthritis, coupled with increased sensory innervation. The sensory PGE2/EP4 pathway is involved in the regulation of bone mass accrual by the induction...

  • Article
  • Open Access
23 Citations
8,218 Views
19 Pages

9 February 2021

Maternal obesity, a state of chronic low-grade metabolic inflammation, is a growing health burden associated with offspring adiposity, abnormal fetal growth and prematurity, which are all linked to adverse offspring cardiometabolic health. Higher int...