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13 Results Found

  • Article
  • Open Access
6 Citations
6,271 Views
17 Pages

In consideration of its relatively constant urinary excretion rate, creatinine (2-amino-1-methyl-5H-imidazol-4-one, MW 113.1) in urine is a useful endogenous biochemical parameter to correct the urinary excretion rate of numerous endogenous and exoge...

  • Article
  • Open Access
1 Citations
3,166 Views
20 Pages

13 December 2024

Silylation is a widely used derivatization technique for the gas chromatographic analysis of benzodiazepines, a class of psychoactive drugs commonly encountered in forensic and biological samples. This study investigated the optimal experimental cond...

  • Article
  • Open Access
2,234 Views
16 Pages

Associations of Amino Acids with the Risk of Prediabetes: A Case-Control Study from Kazakhstan

  • Alma Nurtazina,
  • Ivan Voitsekhovskiy,
  • Bakyt Kanapiyanov,
  • Maxat Toishimanov,
  • Daulet Dautov,
  • Kairat Karibayev,
  • Yerbol Smail,
  • Dana Kozhakhmetova and
  • Altay Dyussupov

21 October 2024

Background: The high global prevalence of prediabetes requires its early identification. Amino acids (AAs) have emerged as potential predictors of prediabetes. This study investigates the association between amino acids and prediabetes in the Kazakh...

  • Article
  • Open Access
17 Citations
4,003 Views
13 Pages

6 August 2020

A low solvent consumption method for the determination of non-steroidal anti-inflammatory drugs (NSAIDs) in animal urine samples is studied. The NSAIDs were extracted with CH2Cl2 by the ultrasound vortex assisted dispersive liquid–liquid microe...

  • Feature Paper
  • Article
  • Open Access
3 Citations
2,802 Views
17 Pages

26 June 2022

The concentrations of seventeen endocrine disruptor compounds (EDCs) that included oestrogens, phytoestrogens, sitosterol, and banned industrial pollutants were investigated at ten sites of the Douro River estuary. Surface waters were collected durin...

  • Article
  • Open Access
8 Citations
4,314 Views
16 Pages

Development of a New Biomarker Model for Predicting Preterm Birth in Cervicovaginal Fluid

  • Ji-Youn Lee,
  • Sumin Seo,
  • Bohyun Shin,
  • Se Hee Hong,
  • Eunjin Kwon,
  • Sunwha Park,
  • Young Min Hur,
  • Dong-Kyu Lee,
  • Young Ju Kim and
  • Sang Beom Han

9 August 2022

Preterm birth (PTB) is a social problem that adversely affects not only the survival rate of the fetus, but also the premature babies and families, so there is an urgent need to find accurate biomarkers. We noted that among causes, eubiosis of the va...

  • Article
  • Open Access
18 Citations
4,783 Views
9 Pages

Simultaneous Quantification of Opioids in Blood and Urine by Gas Chromatography-Mass Spectrometer with Modified Dispersive Solid-Phase Extraction Technique

  • Sara Yasien,
  • Ejaz Ali,
  • Mohsin Javed,
  • Muhammad Muntazir Iqbal,
  • Shahid Iqbal,
  • Hamad Alrbyawi,
  • Samar O. Aljazzar,
  • Eslam B. Elkaeed,
  • Ayed A. Dera and
  • Abd-ElAziem Farouk
  • + 1 author

10 October 2022

Common methodologies such as liquid-liquid extraction and solid-phase extraction are applied for the extraction of opioids from biological specimens i.e., blood and urine. Techniques including LC-MS/LC-MSMS, GC-MS, etc. are used for qualitative or qu...

  • Article
  • Open Access
26 Citations
6,107 Views
8 Pages

Optimization and Application of a GC-MS Method for the Determination of Endocrine Disruptor Compounds in Natural Water

  • José Gustavo Ronderos-Lara,
  • Hugo Saldarriaga-Noreña,
  • Mario Alfonso Murillo-Tovar and
  • Josefina Vergara-Sánchez

Bisphenol A (BPA), 4-nonylphenol (4NP), estradiol (E2), and ethinylestradiol (EE2) are considered as endocrine disruptors or mutagens. These compounds are commonly called endocrine disrupter chemicals (EDCs). BPA and 4NP are widely used as plastic ad...

  • Article
  • Open Access
1 Citations
1,366 Views
21 Pages

16 July 2025

Aroma is an important indicator for evaluating the quality of baijiu. In this study, we determined the aroma-active compounds in four representative brands of strong-aroma baijiu from Sichuan and Jianghuai regions through GC-MS/O, and GC-TOF-MS quant...

  • Article
  • Open Access
15 Citations
8,607 Views
13 Pages

NSAIDs Determination in Human Serum by GC-MS

  • Adamantios Krokos,
  • Elisavet Tsakelidou,
  • Eleni Michopoulou,
  • Nikolaos Raikos,
  • Georgios Theodoridis and
  • Helen Gika

Non-steroidal anti-inflammatory drugs (NSAIDs) are being widely consumed without medical prescription and are often the cause of intoxication, usually in young children. For this, there is a special need in their determination in routine toxicology a...

  • Article
  • Open Access
2 Citations
2,971 Views
16 Pages

Background: Cannabis oil titration consists of quantification of the acidic precursors tetrahydrocannabinolic acid (THCA) and cannabidiolic acid (CBDA) and their decarboxylated products, the active neutral cannabinoids delta-9-tetrahydrocannabinol (&...

  • Article
  • Open Access
7 Citations
2,458 Views
17 Pages

Sloanea chocoana and S. pittieriana (Elaeocarpaceae): Chemical and Biological Studies of Ethanolic Extracts and Skincare Properties

  • Patricia Quintero-Rincón,
  • Nayive Pino-Benítez,
  • Elkin Galeano,
  • Cris Rojo-Uribe,
  • Ana C. Mesa-Arango and
  • Oscar A. Flórez-Acosta

24 November 2023

The Colombian Chocó is known for its rich biodiversity and to harbor plant species that are under-explored, including the genus Sloanea. This study aimed to analyze the chemical composition of derivatized ethanolic extracts from S. chocoana an...

  • Article
  • Open Access
7 Citations
3,081 Views
20 Pages

Chemical Characterization and Several Bioactivities of Cladanthus mixtus from Morocco

  • Amina El Mihyaoui,
  • El Hadi Erbiai,
  • Saoulajan Charfi,
  • Eugénia Pinto,
  • María Emilia Candela Castillo,
  • Josefa Hernández-Ruiz,
  • Antonio Cano,
  • Alain Badoc,
  • Ahmed Lamarti and
  • Marino B. Arnao

The purpose of this work was to investigate, for the first time to our knowledge, the chemical composition and bioactivity of methanolic extracts (roots, stems, leaves, and flowers) from Cladanthus mixtus (L.) Chevall. that grows wild in northern Mor...