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11 Results Found

  • Article
  • Open Access
7 Citations
7,153 Views
12 Pages

7 July 2017

The results of the full-scale testing of the Extruded Briquettes (BREX) as the charge components of the industrial Midrex reactor are discussed. The influence of the type of binder on the degree of metallization of BREX is analyzed. Magnesium sulfate...

  • Article
  • Open Access
1 Citations
3,432 Views
13 Pages

5 February 2024

Kristen Sandrock (2020) connects John Lanchester’s 2019 Brexit novel The Wall with what she refers to as ‘British border epistemologies’; that is, a radical process of re-bordering due to global warming and its impact on human mobil...

  • Proceeding Paper
  • Open Access
1,388 Views
6 Pages

MspGI Restriction–Modification System and Its Flanking Genes of Microbacterium sp. Gd 4-13

  • Alfiya K. Yunusova,
  • Elena V. Spirina,
  • Valeriya N. Antipova and
  • Rimma I. Artyukh

Bacteria have defense systems against the penetration of foreign DNA (phages and plasmids). Some defense systems protect bacteria from phage penetration into the cell, while others block phage replication. Antiphage defense systems are often located...

  • Article
  • Open Access
12 Citations
4,116 Views
19 Pages

Several atypical antipsychotics exert mood-stabilising effects via the modulation of various monoamine receptors and intracellular signallings. Recent pharmacodynamic studies suggested that tripartite synaptic transmission can contribute to the patho...

  • Article
  • Open Access
47 Citations
6,875 Views
24 Pages

Potential Associations Among Alteration of Salivary miRNAs, Saliva Microbiome Structure, and Cognitive Impairments in Autistic Children

  • Marco Ragusa,
  • Maria Santagati,
  • Federica Mirabella,
  • Giovanni Lauretta,
  • Matilde Cirnigliaro,
  • Duilia Brex,
  • Cristina Barbagallo,
  • Carla Noemi Domini,
  • Mariangela Gulisano and
  • Michele Purrello
  • + 9 authors

27 August 2020

Recent evidence has demonstrated that salivary molecules, as well as bacterial populations, can be perturbed by several pathological conditions, including neuro-psychiatric diseases. This relationship between brain functionality and saliva compositio...

  • Article
  • Open Access
174 Citations
9,942 Views
13 Pages

CircSMARCA5 Inhibits Migration of Glioblastoma Multiforme Cells by Regulating a Molecular Axis Involving Splicing Factors SRSF1/SRSF3/PTB

  • Davide Barbagallo,
  • Angela Caponnetto,
  • Matilde Cirnigliaro,
  • Duilia Brex,
  • Cristina Barbagallo,
  • Floriana D’Angeli,
  • Antonio Morrone,
  • Rosario Caltabiano,
  • Giuseppe Maria Barbagallo and
  • Michele Purrello
  • + 3 authors

Circular RNAs (circRNAs) have recently emerged as a new class of RNAs, highly enriched in the brain and very stable within cells, exosomes and body fluids. To analyze their involvement in glioblastoma multiforme (GBM) pathogenesis, we assayed the exp...

  • Article
  • Open Access
54 Citations
4,792 Views
16 Pages

The GAUGAA Motif Is Responsible for the Binding between circSMARCA5 and SRSF1 and Related Downstream Effects on Glioblastoma Multiforme Cell Migration and Angiogenic Potential

  • Davide Barbagallo,
  • Angela Caponnetto,
  • Cristina Barbagallo,
  • Rosalia Battaglia,
  • Federica Mirabella,
  • Duilia Brex,
  • Michele Stella,
  • Giuseppe Broggi,
  • Roberto Altieri and
  • Michele Purrello
  • + 8 authors

7 February 2021

Circular RNAs (circRNAs) are a large class of RNAs with regulatory functions within cells. We recently showed that circSMARCA5 is a tumor suppressor in glioblastoma multiforme (GBM) and acts as a decoy for Serine and Arginine Rich Splicing Factor 1 (...

  • Article
  • Open Access
169 Citations
7,360 Views
12 Pages

CircSMARCA5 Regulates VEGFA mRNA Splicing and Angiogenesis in Glioblastoma Multiforme Through the Binding of SRSF1

  • Davide Barbagallo,
  • Angela Caponnetto,
  • Duilia Brex,
  • Federica Mirabella,
  • Cristina Barbagallo,
  • Giovanni Lauretta,
  • Antonio Morrone,
  • Francesco Certo,
  • Giuseppe Broggi and
  • Michele Purrello
  • + 6 authors

7 February 2019

Circular RNAs are a large group of RNAs whose cellular functions are still being investigated. We recently proposed that circSMARCA5 acts as sponge for the splicing factor Serine and Arginine Rich Splicing Factor 1 (SRSF1) in glioblastoma multiforme...

  • Article
  • Open Access
8 Citations
5,175 Views
18 Pages

Genomic Analysis Unveils the Pervasiveness and Diversity of Prophages Infecting Erwinia Species

  • Tulio Morgan,
  • Rafael Reis de Rezende,
  • Thamylles Thuany Mayrink Lima,
  • Flávia de Oliveira Souza and
  • Poliane Alfenas-Zerbini

27 December 2022

Prophages are abundant elements integrated into bacterial genomes and contribute to inter-strain genetic variability and, in some cases, modulate the environmental behavior of bacteria, such as pathogen virulence. Here, we described prophage occurren...

  • Article
  • Open Access
17 Citations
5,567 Views
19 Pages

31 May 2018

Burkholderia cenocepacia, is a Gram-negative opportunistic pathogen that belongs to Burkholderia cepacia complex (BCC) group. BCC representatives carry various pathogenicity factors and can infect humans and plants. Phages as bacterial viruses play a...

  • Article
  • Open Access
1 Citations
7,593 Views
16 Pages

6 August 2020

The Busang mineral prospect in Kalimantan, Indonesia, was reported to host a large Au resource until 1997 when it was revealed that drill core samples had been deliberately and systematically contaminated (“salted”) with extraneous Au to...