Viruses–Bacteria Interactions in the Gut

Dear Colleagues,

Acute gastroenteritis is the second leading cause of death in children under five years of age worldwide, and a major cause of illness. Pathogenic bacteria and viruses are often the culprits, but commensal microbiota and host modulate symptoms and disease outcomes. While the interaction of viruses and bacteria in the lung have been extensively studied, and molecular mechanisms are emerging, how parallel interactions between bacteria and viruses in the intestine influence bacterial or viral pathogenesis and overall health outcomes have not been studied widely. This Special Issue of Viruses is dedicated to exploring and discussing many aspects of the “transkingdom” interactions between viruses and bacteria in the gut, and how they influence health and disease. We hope to assemble a collection of research papers and reviews that together will offer a comprehensive view on this emerging field, which summarizes our current understanding and identifies open research questions to stimulate interdisciplinary research in this area in the future. Topics may include (but are not limited to) the interplay between enteric viruses, pathogenic bacteria and/or the microbiota, the host immune response and cellular physiology in the intestine, structure–function studies of the interactions between viruses and bacteria, approaches to model intestinal infections, epidemiological and clinical studies of co-infections, and therapeutic strategies.

Dr. Christiane Wobus
Dr. Megan Baldridge
Guest Editors

Manuscript Submission Information

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