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Special Issue "LCMV – A Pillar for Immunology Research"

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Animal Viruses".

Deadline for manuscript submissions: 15 January 2019

Special Issue Editor

Guest Editor
Dr. Markus J. Hofer

School of Life and Environmental Sciences, The University of Sydney, Australia
Website | E-Mail
Interests: neuroimmunology; neuropathology; neuroinflammation; antiviral responses

Special Issue Information

Dear Colleagues,

Since its original description by Charles Armstrong in 1934, lymphocytic choriomeningitis virus (LCMV) has been a useful instrument in the immunologists’ toolbox. LCMV has been central to the discovery of a wide range of immunological concepts, both relevant to the antiviral host response and beyond. They include ground-breaking experiments by Rolf Zinkernagel and Peter Doherty that led to the discovery of MHC molecules and ultimately the concept of self tolerance, and Michael Oldstone’s work on viral immunopathology and chronic infection. Likewise, the seminal works of Rafi Ahmed, E. John Wherry and many others to characterise functional T cell exhaustion laid the foundation for the development of new treatments for chronic infections and malignant diseases. There is no doubt that the study of LCMV will continue to open new avenues of research in immunology.

The goal of this Special Issue is to assemble both reviews and original research manuscripts that focus on LCMV as both a model and pathogen to illuminate the diverse nature of anti-viral responses.

Dr. Markus J. Hofer
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Lymphocytic choriomeningitis virus
  • LCMV
  • Acute versus chronic infection
  • Innate antiviral response
  • Adaptive antiviral response
  • Immune cell exhaustion
  • CNS infection and neurological disease
  • Human infection

Published Papers

This special issue is now open for submission.
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