Bioinformatics and Computational Approaches in Viral Genomics and Evolution 2025–2026

Dear Colleagues,

We are pleased to invite submissions to a Special Issue of Viruses titled “Bioinformatics and Computational Approaches in Viral Genomics and Evolution 2025–2026”.

The rapid evolution of viral pathogens and the urgency for surveillance of emergent and reemergent viruses highlight the critical need for advanced computational methods in understanding their behavior, transmission, and adaptation. The integration of bioinformatics tools and genomic data analysis is essential for monitoring viral evolution, predicting new threats, and developing targeted interventions.

This Special Issue seeks to highlight innovative computational techniques, including genome-wide analysis, pipelines for NGS-generated genome assembly, phylogenetic modeling, and machine learning approaches, to study viral evolution. We welcome original research, reviews, and short communications on topics such as:

• Bioinformatics tools for viral genome analysis and surveillance;
• Computational methods for studying viral evolution and mutation;
• Integration of genomic data with clinical and epidemiological information;
• Computational models for understanding viral–host interactions and pathogenicity;
• Advances in computational epidemiology and viral surveillance networks.

We invite contributions that advance our understanding of viral genomics, providing insights that will assist in the global fight against infectious diseases. We look forward to your submissions.

Dr. Camila Malta Romano
Prof. Dr. Mariana Severo Ramundo
Dr. Nilson Coimbra
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.