Research on Innate Immunity and Inflammation
A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Innate and Adaptive Immunity in Vaccination".
Deadline for manuscript submissions: closed (30 April 2020) | Viewed by 52786
Special Issue Editors
Interests: hepatitis C; molecular virology; innate immunity; virus-host interaction; antibody; inflammation; immunopathology; vaccine
Special Issues, Collections and Topics in MDPI journals
Interests: HIV; hepatitis C; infectious diseases; immunology; virology; genetics; epidemiology; cirrhosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Innate immunity and inflammation are closely interrelated and constitute an exciting field of intense investigation in multiple disciplines. Invading pathogens are detected by the host pattern recognition receptors (PRRs), which trigger intracellular immune signaling pathways to promote inflammation. This innate response is crucial to clear the infection and controlling adaptive immunity. Inflammation, however, has to be strictly controlled to avoid excessive host damage. Thus, the immune signaling pathways are tightly regulated to ensure a balanced inflammatory response. Therefore, we would like to encourage the presentation to this special issue recent advances in the understanding of the mechanisms of pathogen recognition by PRRs and their regulation (including post-translational modifications), as well as in the escape mechanisms and countermeasures developed by microbes and host, respectively. Identification of surrogate biomarkers defining early signatures of vaccine-induced inflammation may help to select safe candidate vaccines. Articles on this topic will also be welcome. Adding new information on these subjects may lead to a better understanding of the pathogenesis of different diseases and aid in the design of new therapeutic and prophylactic strategies.
Dr. Isidoro Martínez
Dr. Salvador Resino
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Innate Immunity
- Inflammation
- pattern recognition receptors
- immune signaling pathways
- vaccines
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