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Toxics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Exposure, Pathways and Assessment of (Eco)Toxicity of Nanomaterials

edited by

Gang Liang

submission deadline 20 Nov 2025 | Viewed by 134 | Submission Open

Keywords: toxicity; risk assessment; ecotoxicological effect; analytical methods; emerging nanomaterials

(This special issue belongs to the Section Ecotoxicology)

Environmental Monitoring and Health Risk Assessment of Traffic-Related Air Pollution

edited by

Huanbo Wang

, Tingting Huo and

Li Zhou

submission deadline 20 Nov 2025 | Viewed by 101 | Submission Open

Keywords: air pollution; particulate matter; health risk assessment; vehicle emission; reactive oxygen species (ROS)

(This special issue belongs to the Section Air Pollution and Health)

Multi-Media Environmental Pollution and Health Risks: Tracing, Effects, and Collaborative Governance

edited by

Dexin Liu

Jianbiao Peng

and Lihong Ren

submission deadline 21 Nov 2025 | 3 articles | Viewed by 1947 | Submission Open

Keywords: atmosphere; water; soil; sediment; pollutants; source apportionment; risk assessment; human exposure; pollution control; environmental pollution; health risks; heavy metal; environmental toxicology; ecotoxicology

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

New Approach Methodologies in Environmental Risk Assessment of Chemical Contaminants

edited by

Carlos Barata

submission deadline 21 Nov 2025 | Viewed by 169 | Submission Open

Keywords: approaches for pollution assessment; ecotoxicology; ecological effects; new approach methodologies; chemical toxicity; chemical contaminants; risk assessment

(This special issue belongs to the Section Ecotoxicology)

Neuronal Injury and Disease Induced by Environmental Toxicants

edited by

Jun Wang

and

Guixiang Ji

submission deadline 25 Nov 2025 | 6 articles | Viewed by 7936 | Submission Open

Keywords: neurotoxicology; neural injury and mechanisms; chemical exposure; neurodegenerative diseases; psychiatric disorders; toxicomics; toxic intervention

(This special issue belongs to the Section Neurotoxicity)

State-of-the-Art Environmental Chemical Exposomics and Metabolomics—2nd Edition

edited by

Minjian Chen

submission deadline 25 Nov 2025 | 4 articles | Viewed by 6846 | Submission Open

Keywords: exposomics; metabolomics; exposome; exposure; metabolome; metabolism; health; toxicity

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Emissions, Environmental Behavior, Pollution Distribution, Modeling, and Risk Assessment of Persistent Organic Pollutants (POPs)

edited by Ye Huang

submission deadline 25 Nov 2025 | 2 articles | Viewed by 5956 | Submission Open

Keywords: persistent organic pollutants (POPs); emission inventory; environmental behavior; pollution distribution; risk assessment; modeling techniques; remediation strategies

(This special issue belongs to the Section Emerging Contaminants)

Airway Exposure to Pollution from Ambient Particulate Matter (PM) and Health Effects

edited by

Gloria Melzi

and

Yuewei Liu

submission deadline 28 Nov 2025 | 3 articles | Viewed by 2307 | Submission Open

Keywords: air pollution; particulate matter (PM); respiratory health; airway inflammation; oxidative stress; in vitro toxicology; alternative testing methods; cell culture models; health risk assessment

(This special issue belongs to the Section Air Pollution and Health)

Health Risk Assessment for Food Contaminants: Exposure and Human Toxicology

edited by

Yu-Syuan Luo

and

Nan-Hung Hsieh

submission deadline 28 Nov 2025 | Viewed by 110 | Submission Open

Keywords: food contaminants; health risk assessment; exposure modeling; toxicology; new approach methodologies (NAMs)

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Biological Risk Monitoring of Exposure to Chemical Pollutants and/or Physical Agents: 2nd Edition

edited by

Mirta Milić

and

Nursen Basaran

submission deadline 29 Nov 2025 | 1 articles | Viewed by 2961 | Submission Open

Keywords: biomarkers of effect; biomarkers of exposure; biomarkers of susceptibility; DNA damage and repair; meta-analysis; biomonitoring; exposure; toxicokinetics and modes of action; risk assessment; epidemiology

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Concentration of VOCs in the Atmosphere and Its Environmental Exposure

edited by

Xinlei Ge

and

Ming Wang

submission deadline 30 Nov 2025 | 4 articles | Viewed by 3430 | Submission Open

Keywords: VOCs; health risk assessment; exposure assessment; source identification; environmental impact

(This special issue belongs to the Section Emerging Contaminants)

Identification of Emerging Pollutants and Human Exposure

edited by

Xiaotu Liu

and

Ting Wu

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1515 | Submission Open

Keywords: emerging contaminants; remediation strategies; non-targeted analysis; biomonitoring; exposome; risk assessment

Human Biomonitoring Studies: Environmental Pollution and Possible Risks to Human Health

edited by

Valentina Marra

Anna Maria Ingelido

and Silvia Valentini

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1062 | Submission Open

Keywords: air pollution human biomonitoring; biological matrices (serum; urine; milk); exposure assessment; exposure biomarkers; reproductive toxicity; adults; children; reproductive age; emerging compounds; persistent organic compounds

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Biological Effects and Mechanisms of Environmental Endocrine Disruptors

edited by Liting Zhou

submission deadline 30 Nov 2025 | 1 articles | Viewed by 862 | Submission Open

Keywords: environmental endocrine disruptors; epidemiological research; health effects; mixed exposure; emerging experimental models; mechanism

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Hazardous Pollutants in Marine Ecosystems

edited by

Maria Luisa Vannuccini

and Inmaculada Varó

submission deadline 30 Nov 2025 | 1 articles | Viewed by 323 | Submission Open

Keywords: ecotoxicology; nanomaterials; bioaccumulation; biotransformation; biomonitoring; POPs; PAHs

Emerging Pollutants in the Aquatic Ecosystems: Occurrence, Fate and Effects on the Dissemination of Antibiotic Resistance Genes

edited by Lijun Zhou and Liangying He

submission deadline 30 Nov 2025 | Viewed by 263 | Submission Open

Keywords: antibiotics; antibiotic resistance genes; emerging pollutant; PPCPs; biocides; occurrence; ecological risk; horizontal gene transfer

(This special issue belongs to the Section Emerging Contaminants)

Migration and Transformation of Emerging Pollutants and Improvement of Water Quality

edited by Shibao Lu and

Liang Pei

submission deadline 30 Nov 2025 | Viewed by 154 | Submission Open

Keywords: pollutant fate and transport; emerging contaminants; water remediation technologies; environmental nanotechnology; hydrobiogeochemical cycles; smart water management

From Detection to Risk: Data-Driven Advances in Analytical Chemistry and Toxicology

edited by

Nikiforos Alygizakis

submission deadline 30 Nov 2025 | Viewed by 144 | Submission Open

Keywords: analytical chemistry; computational mass spectrometry; toxicology; exposure assessment; chemical prioritization; mixture toxicity; environmental risk assessment

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Fish Physiological Responses to Environmental Stressors

edited by

Jun Wang

submission deadline 30 Nov 2025 | Viewed by 120 | Submission Open

Keywords: fish ecotoxicology; physiological disruption; oxidative stress biomarkers; ecological risk assessment; bioaccumulation dynamics; endocrine disruption; population changes

(This special issue belongs to the Section Ecotoxicology)

Biomonitoring for Emerging Contaminants: From Detection to Risk Assessment

edited by Wenlong Li

submission deadline 10 Dec 2025 | 1 articles | Viewed by 898 | Submission Open

Keywords: biomonitoring; emerging contaminants; risk assessment; detection; identification

Selected Papers from the 2nd International Online Conference on Toxics (IOCTO2025)

edited by

Xiaojun Luo

Mingce Long

, Patricia Ruiz and Maria João Bebianno

submission deadline 10 Dec 2025 | Viewed by 450 | Submission Open

Keywords: toxicology methods; toxicological mechanisms; organ toxicity; predictive toxicology

Evaluation and Biomonitoring of Potentially Toxic and Rare Earth Elements

edited by Ángel Rodríguez Hernández,

Manuel L Zumbado

and Carmen José Mateos Vega

submission deadline 19 Dec 2025 | 1 articles | Viewed by 581 | Submission Open

Keywords: potentially toxic elements (PTEs); rare earth elements (REEs); human biomonitoring; animal biomonitoring; environmental pollution; toxicological effects; risk assessment; oxidative stress; public health

Editorial Board Members’ Collection Series: Endocrine Disrupting Chemicals

edited by

Eduardo Rocha

and

Jing Liu

submission deadline 20 Dec 2025 | 3 articles | Viewed by 8697 | Submission Open

Keywords: EDCs; endocrine disruption; endocrine disorders; one health; xenohormones; environmental toxicology; mixture toxicity; plastics; pollution; reproductive toxicology

(This special issue belongs to the Section Emerging Contaminants)

Understanding the Trafficking of Toxic Metal(loid)s within Cells

edited by

Maikel Rosabal

and

Jürgen Gailer

submission deadline 20 Dec 2025 | 1 articles | Viewed by 1276 | Submission Open

Keywords: subcellular toxicity; metal interactions; subcellular targets; molecular toxicity; organelles; detoxification; adverse effects; aquatic and terrestrial animals; human models

(This special issue belongs to the Section Metals and Radioactive Substances)

Environmental Toxicology and Risk Assessment of Priority Substances

edited by

Xin Zheng

, Tianxu Zhang and Shuhui Men

submission deadline 28 Dec 2025 | 7 articles | Viewed by 8294 | Submission Open

Keywords: Environmental toxicology; Risk assessment; Priority substances; New Approach Methodologies (NAMs); Emerging contaminant monitoring; Toxicity effects; Microcosm experiments

(This special issue belongs to the Section Emerging Contaminants)

Heavy Metals and Pesticide Residue Remediation in Farmland

edited by Ying Huang

submission deadline 30 Dec 2025 | 1 articles | Viewed by 507 | Submission Open

Keywords: heavy metal; pesticide residues; photocatalytic degradation; pollution evaluation; rice; combined pollution; phytoremediation; source; transfer; and accumulation

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Toxic Mode of Action, Toxicity Testing, and Health Risks of Environmental Pollutants

edited by Weiwei Zheng and

Yuanyuan Ruan

submission deadline 31 Dec 2025 | 6 articles | Viewed by 23961 | Submission Open

Keywords: mode of action; toxicity testing; health risks; risk assessment; environmental pollutants

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Unraveling the Health Impacts of Air Pollution: Assessments and Mechanisms

edited by

Ting Wang

, Tingting Ku and

Jia Xu

submission deadline 31 Dec 2025 | 8 articles | Viewed by 9260 | Submission Open

Keywords: air pollution; exposure assessment; epidemiological study; toxic mechanisms; key components; health effects

(This special issue belongs to the Section Air Pollution and Health)

Impact of Per- and Polyfluoroalkyl Substances (PFAS) on Aquatic Animals: Immunotoxicity, Endocrine Disruption, and Beyond

edited by

Maurizio Manera

and

Luisa Giari

submission deadline 31 Dec 2025 | 3 articles | Viewed by 8492 | Submission Open

Keywords: new and old PFAS; animal model; one health; biomarker; immune system; endocrine system; toxic effects; in vivo and in vitro exposures

(This special issue belongs to the Section Ecotoxicology)

Ototoxic Chemical Exposures and Public Health

edited by

Thais C. Morata

, Gregory Zarus and Krystin Carlson

submission deadline 31 Dec 2025 | 2 articles | Viewed by 8203 | Submission Open

Keywords: early detection; diagnosis; treatment; prevention; occupational exposures; hearing; vestibular/balance; tinnitus/ringing

(This special issue belongs to the Section Human Toxicology and Epidemiology)

The Environment and Reproduction: Toxicity Assessment of Pollutant Exposure

edited by

Luigi Montano

submission deadline 31 Dec 2025 | 1 articles | Viewed by 7247 | Submission Open

Keywords: environmental toxicology; reproductive toxicity; pollutant exposure; endocrine disruptors; chemical pollutants; ecotoxicology; teratogenicity; bioaccumulation

(This special issue belongs to the Section Reproductive and Developmental Toxicity)

Biomass Conversion and Organic Waste Utilization in Wastewater

edited by

Tingting Zhu

, Zisheng Zhao and Lihui Yang

submission deadline 31 Dec 2025 | 4 articles | Viewed by 5623 | Submission Open

Keywords: organic wastewater; resource recovery; biomass conversion; added value products; energy recovery

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Carbon-Based Materials for Pollutant Immobilization and Removal in Soil and Water

edited by

Jianxin Fan

submission deadline 31 Dec 2025 | 3 articles | Viewed by 4256 | Submission Open

Keywords: carbon-based materials; emerging pollutants; heavy metals; immobilization; removal

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Impact of Pollutants on Aquatic Ecosystems and Food Safety

edited by Francesca Falco

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3223 | Submission Open

Keywords: multi-stress; enviromental biodiversity; cascading effect; emerging contaminants; ecotoxicology; biomarkers

(This special issue belongs to the Section Emerging Contaminants)

Advances in Computational Methods of Studying Exposure to Chemicals

edited by Patricia Ruiz and Wei-Chun Chou

submission deadline 31 Dec 2025 | 1 articles | Viewed by 3058 | Submission Open

Keywords: computational toxicology; machine learning; quantitative structure-activity relationship (QSAR); in silico modeling; molecular docking and molecular dynamics simulations; PBPK and PK modeling; fate and transport modeling; high-throughput screening (HTS); integrated testing strategies (ITS); artificial intelligence; risk assessment; adverse outcome pathway (AOP); new approach methodologies (NAMs); chemical mixtures

(This special issue belongs to the Section Novel Methods in Toxicology Research)

The Neuroexposome: Integrating Exposures with Physiology to Understand Brain Health and Disease

edited by Megan Mahoney and

Jennifer L. Freeman

submission deadline 31 Dec 2025 | 3 articles | Viewed by 2669 | Submission Open

Keywords: exposome; exposomics; neuroexposome; neurodegeneration; neurotoxicology; neurodevelopment; developmental origins of health and disease (DOHAD)

(This special issue belongs to the Section Neurotoxicity)

Perspectives in Veterinary Toxicology and One Health

edited by

Wilson Kiiza Rumbeiha

and Abdel-Razak Kadry

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2211 | Submission Open

Keywords: climate change and animal health; animals as biosentinels of environmental pollution; pollutants and animal health; one health toxicology; veterinary toxicology; environmental toxicants modulating animal health

Environmental Contaminant Exposure and Intake from Agricultural Products

edited by Sara Lambiase and

Mauro Esposito

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2143 | Submission Open

Keywords: persistent organic pollutants; metals and metalloids; emerging contaminants; targeted and untargeted analyses; food safety; feed safety; risk assessment

(This special issue belongs to the Section Agrochemicals and Food Toxicology)

Ecotoxicological Effects of Microplastics on the Soil Environment

edited by

Rogers Wainkwa Chia

, Charles Amanze and Modupe Elizabeth Ojewumi

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1777 | Submission Open

Keywords: microplastics; soil ecosystems; soil fertility; food security; ecotoxicological risks; soil contamination; sustainable waste management

(This special issue belongs to the Section Ecotoxicology)

Applicability of New Approach Methodologies (NAMs) to Skin Sensitization: Insights from Industry and Regulatory Perspectives

edited by Gertrude-Emilia Costin and Argel Islas-Robles

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1351 | Submission Open

Keywords: skin sensitization; allergic contact dermatitis; new approach methodologies; regulatory testing; defined approaches; adverse outcome pathway; cosmetic industry; medical devices; mixtures; botanicals

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Pharmacological Intervention Against Toxicity of Environmental Pollutants and Stresses

edited by

Dayong Wang

Natalia Krasteva

and Tianshu Wu

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1256 | Submission Open

Keywords: toxicology; ecotoxicology; pharmacology; environmental pollutant; environmental stress; health protection

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Environmental Contamination, Toxic Effect, and Risk Assessment of Microplastics and Plastic Additives

edited by

Yu Wang

Chu Peng

and

Lili Rong

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1096 | Submission Open

Keywords: microplastics; plastic additives; environmental contamination; biomonitoring; bioaccumulation; toxicity mechanism; ecological risk assessment; human health effect

(This special issue belongs to the Section Emerging Contaminants)

Endocrine Disruptors and Persistent Organic Pollutants: Their Impact on the Environment and Human Health

edited by Euripides G. Stephanou and

Antonis Myridakis

submission deadline 31 Dec 2025 | 1 articles | Viewed by 819 | Submission Open

Keywords: biomonitoring of EDCs and POPs; Prenatal exposure to mixtures of endocrine-disrupting chemicals and respiratory health in children; exposure to POPs and emotional and behavioral outcomes from early childhood to adolescence

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Environmental Behavior and Migration Mechanism of Microplastics

edited by

Jiji Li

and

Fabiana Corami

submission deadline 31 Dec 2025 | Viewed by 439 | Submission Open

Keywords: environmental toxicology; emerging methodologies; risk assessment; omics technologies; chemical mixtures; nanomaterials; in silico models

Detection and Degradation of Organic Pollutants

edited by

Dongyang He

Jiao Qu

and Xiaolin Zhu

submission deadline 31 Dec 2025 | Viewed by 247 | Submission Open

Keywords: pollutant detection; quantitative detection; sensor; toxicity; pollutant degradation; photocatalysis; electrocatalysis

Emerging Pollutants and Livestock Health

edited by

Shuhua Yang

Shu-cheng Huang

and Yuhang Sun

submission deadline 31 Dec 2025 | Viewed by 222 | Submission Open

Keywords: mycotoxin; endocrine disrupting chemicals; heavy-metal pollution; microplastics; toxin; detoxicant; persistent organic pollutants

Impact of Toxic and Harmful Volatile Organic Compounds on Health and Ecology

edited by

Hong Li

Junling Li

and Yuanyuan Ji

submission deadline 31 Dec 2025 | Viewed by 148 | Submission Open

Keywords: anthropogenic and natural emissions of atmospheric VOCs; transformation; transport and deposition of atmospheric VOCs; impact of VOCs on the atmospheric environment; human health risk assessment of toxic atmospheric VOCs; characterization; sources and control of ODS; monitoring; alternative abatement technologies and environmental impact of fluorinated greenhouse gases; sources analysis techniques for atmospheric VOCs

Cadmium Exposure and Health Impact

edited by

Teresa Urbano

and

Tommaso Filippini

submission deadline 31 Dec 2025 | Viewed by 134 | Submission Open

Keywords: sources and pathways of cadmium exposure; with a particular focus on diet; mechanisms of cadmium toxicity; genomic and epigenomic effects of cadmium; cadmium exposure and bone metabolism; cancer; cardiovascular; kidney; and neurodegenerative diseases; vulnerable populations and susceptibility to cadmium exposure; biomarkers of cadmium exposure; public health implications of cadmium exposure

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Biochar-Enhanced Remediation of Heavy Metal-Induced Soil and Water Environmental Degradation: Microbial and Functional Material Perspectives

edited by

Longfei Liu

Shengsen Wang

and

Wan Yang

submission deadline 31 Dec 2025 | Viewed by 133 | Submission Open

Keywords: carbon-based remediation materials; multi-media synergistic remediation; multidimensional ecological risk assessment; microplastic-heavy metal interactive contamination; microinterface modulation technology; co-occurrence of persistent organic pollutants; migration; transformation; and fate of heavy metals

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Occurrence, Fate, Bioaccumulation and Toxic Effects of 6PPDQ

edited by