Cadmium Exposure and Health Impact

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Exposome Analysis and Risk Assessment".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 9

Special Issue Editors


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Guest Editor
Department of Biomedical, Metabolic, and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Interests: child and adolescent health; chronic disease; environmental epidemiology; heavy metals; neuroepidemiology; trace elements; urban health

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Guest Editor
CREAGEN-Environmental, Genetic and Nutritional Epidemiology Research Center, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy
Interests: epidemiological methods; environmental and nutritional epidemiology with particular focus on childhood leukemia, neurodegenerative and chronic diseases
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Special Issue Information

Dear Colleagues,

Cadmium, which is a persistent environmental contaminant from natural and human sources, poses a significant public health threat due to its bioaccumulation and long biological half-life. Cadmium and cadmium compounds are classified as human carcinogens by the International Agency for Research on Cancer (IARC); this is based on sufficient evidence of carcinogenicity from human studies. Its toxicity stems from disrupting cellular processes, inducing oxidative stress, and affecting multiple organ systems. Chronic low-level exposure is linked to kidney dysfunction, bone disease, cardiovascular issues, and increased cancer risk. Emerging research also highlights potential neurodevelopmental and endocrine effects. Given its widespread presence, particularly within urban environments where industrial activities, waste disposal, and traffic contribute to elevated levels, and severe health consequences, continued investigation into cadmium exposure is crucial for understanding its mechanisms, identifying vulnerable populations, developing biomarkers, and implementing exposure reduction strategies.

We are pleased to invite you to contribute to the Special Issue “Cadmium Exposure and Health Impact”. 

This Special Issue aims to provide a comprehensive and multidisciplinary exploration of cadmium exposure and its health impacts, encompassing the latest research on its sources, mechanisms of toxicity, epidemiological findings, clinical manifestations, and potential mitigation strategies.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Sources and pathways of cadmium exposure, with a particular focus on diet;
  • Mechanisms of cadmium toxicity;
  • Genomic and epigenomic effects of cadmium;
  • Cadmium exposure and bone metabolism, cancer, cardiovascular, kidney, and neurodegenerative diseases;
  • Vulnerable populations and susceptibility to cadmium exposure;
  • Biomarkers of cadmium exposure;
  • Public health implications of cadmium exposure, including healthcare burdens, societal costs of cadmium-related diseases, lost productivity, and environmental justice issues.

I look forward to receiving your contributions.

Dr. Teresa Urbano
Dr. Tommaso Filippini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sources and pathways of cadmium exposure, with a particular focus on diet
  • mechanisms of cadmium toxicity
  • genomic and epigenomic effects of cadmium
  • cadmium exposure and bone metabolism, cancer, cardiovascular, kidney, and neurodegenerative diseases
  • vulnerable populations and susceptibility to cadmium exposure
  • biomarkers of cadmium exposure
  • public health implications of cadmium exposure

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Published Papers

This special issue is now open for submission.
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