Evaluating DNA Damage and Toxicological Effects
A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Human Toxicology and Epidemiology".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 62
Special Issue Editors
Interests: DNA damage and repair; epigenetics; cancer; aging; nucleosides; medicinal chemistry; protein and DNA biomarkers; proteomics
Interests: the formation of DNA lesions and subsequent mutations; tumor development; carcinogens; molecular inhibitors such as Nitric Oxide and oncometabolites to certain DNA repair enzymes; mutational spectra of bulky DNA lesions; inhibitory effect of nitric oxide on DNA repair enzymes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The human genome is constantly challenged by endogenous and exogenous electrophiles that form potentially toxic and mutagenic DNA adducts. This Special Issue will discuss the role of DNA damage in aging and cancer, focusing on adduct structures, detection methods, and their biological and toxicological outcomes. We will review DNA lesions generated from endogenous reactive species and exogenous damaging agents, including environmental toxins and chemotherapeutic drugs. For detection methods, we will cover various techniques including LC-MS, antibody-based methods, and NMR. For biological outcomes of DNA adducts, we will consider toxicological effects, chemical reactivity, mutagenicity, and toxicity. We will also discuss DNA repair mechanisms. Overall, this Special Issue will review the latest advancements in DNA adducts and their toxicological effects.
Prof. Dr. Natalia Tretyakova
Dr. Deyu Li
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- DNA damage
- DNA repair
- toxicological effect
- nucleic acid biomarker
- DNA adduct
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