Transformation and Exposure Risk of Emerging Contaminants

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Emerging Contaminants".

Deadline for manuscript submissions: closed (8 August 2023) | Viewed by 3149

Special Issue Editors


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Guest Editor
Institute of Environmental Health and Pollution Control, Guangdong University of Technology, Guangzhou, China
Interests: endocrine disrupting chemicals; transformation mechanisms; disinfection by-products; exposure risk of transformation products; quantum chemical calculation

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Guest Editor
School of Environment, Nanjing University, Nanjing, China
Interests: environmental ecology; health risk assessment; risk management and intervention

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Guest Editor
South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, China
Interests: health risk assessment of emerging contaminants (ECs); target & non-target screening analysis of ECs; EC risk control; biomonitoring of human exposure to ECs

Special Issue Information

Dear Colleagues,

Emerging contaminants (ECs) are receiving considerable attention due to their widespread occurrence and toxicological properties. Given their extensive use, ECs continuously undergo biological and chemical degradation in the environment, resulting in the formation of various transformation products (TPs). Several TPs could differ in toxicological effects from the parent ECs. In particular, the formation of higher persistent and/or toxic TPs could result in more adverse impacts on ecosystem and human health. Thus, the transformation and exposure risk of ECs could cause significant environmental, economic, and health effects, making them a problem at the regional, national, and even global scale. This Special Issue aims to be multidisciplinary in its approach covering the latest research on ECs-related transformation and exposure risks.

Research areas may include (but are not limited to) the following:

  • Transformation of ECs in various environmental media (e.g., water, soil, atmosphere, particulate matter).
  • Metabolic transformation ECs in human bodies.
  • Exposure risks of ECs and their transformation products.
  • Monitoring and analysis of transformation/metabolic products.
  • Biomonitoring of human exposure to ECs.
  • Risk management and intervention of ECs.

Prof. Dr. Yanpeng Gao
Prof. Dr. Lei Huang
Prof. Dr. Jing Zheng
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • transformation mechanism
  • environmetnal fate
  • exposure risk
  • emerging contaminants
  • health risk assessment
  • environmental ecology
  • risk management and intervention
  • target & non-target screening analysis
  • biomonitoring of human exposure

Published Papers (2 papers)

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Research

15 pages, 1827 KiB  
Article
Impact of Stove Renovation on PM2.5 Exposure, Risk Perception, Self-Protective Willingness of Rural Residents
by Lei Huang, Yuxin Liu, Yangyang Wu, Ziwen Ye, Futian Ren, Xinlei Liu and Guofeng Shen
Toxics 2023, 11(3), 245; https://doi.org/10.3390/toxics11030245 - 05 Mar 2023
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Abstract
To improve household air quality, the Chinese government has launched a number of pilot stove renovation projects, but few studies have explored the impact of the project on people’s perception of and willingness to participate in these renovations; moreover, factors affecting willingness to [...] Read more.
To improve household air quality, the Chinese government has launched a number of pilot stove renovation projects, but few studies have explored the impact of the project on people’s perception of and willingness to participate in these renovations; moreover, factors affecting willingness to pay for the project in rural China are not yet clear. We conducted a field measurement and a corresponding door-to-door questionnaire survey using the renovated group and the unrenovated group. The results showed that (1) the stove renovation project could not only reduce PM2.5 exposure and the excess mortality risk of rural residents, but also (2) improve residents’ risk perception and self-protective willingness. (3) Specifically, the project had a deeper impact on female and low-income residents. (4) Meanwhile, the higher the income and the larger family size, the higher the risk perception and self-protective willingness. (5) Furthermore, willingness to pay for the project was related with residents’ support for the project, benefit from renovation, income, and family size. Our results recommended that stove renovation policies should pay more attention to families with lower income and smaller size. Full article
(This article belongs to the Special Issue Transformation and Exposure Risk of Emerging Contaminants)
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11 pages, 1642 KiB  
Article
Estrogenic Effect Mechanism and Influencing Factors for Transformation Product Dimer Formed in Preservative Parabens Photolysis
by Xiaolin Niu, Guanhui Chen, Yi Chen, Na Luo, Mei Wang, Xinyi Hu, Yanpeng Gao, Yuemeng Ji and Taicheng An
Toxics 2023, 11(2), 186; https://doi.org/10.3390/toxics11020186 - 17 Feb 2023
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Abstract
The environmental transformation and health effects of endocrine disruptors (EDCs) need urgent attention, particularly the formation of transformation products with higher toxicity than parent EDCs. In this paper, an important transformation product dimer (short for ethyl 4-hydroxy-3-(2-((4-hydroxybenzoyl) oxy) ethyl) benzoate) with estrogenic activity [...] Read more.
The environmental transformation and health effects of endocrine disruptors (EDCs) need urgent attention, particularly the formation of transformation products with higher toxicity than parent EDCs. In this paper, an important transformation product dimer (short for ethyl 4-hydroxy-3-(2-((4-hydroxybenzoyl) oxy) ethyl) benzoate) with estrogenic activity was investigated and detected in the photolysis of preservative ethyl-paraben (EPB) dissolved in actual water. The environmental factors, such as the higher initial concentration of EPB, the stronger optical power and the lower pH could stimulate the formation of the dimer. Simultaneously, the interaction of multiple environmental factors was significant, especially the initial concentration and pH using the response surface methodology. Furthermore, the relationship between the environmental factors and the formation of the product dimer was further explained and the empirical model equation was built for predicting the amount of dimer in actual water. Quantum chemical and toxicological calculations showed the estrogenic effect mechanism of the product dimer and it was revealed further that the hydrogen bonds of the dimer and ERα proteins (ARG-394, Glu-353, His-524, GYY-521) were formed, with a lowest binding energy of −8.38 Kcal/mol during molecular docking. In addition, the health effect risk of the product dimer was higher than the parent compound in the blood, cardiovascular system, gastrointestinal system, kidney and liver. In short, the present study was of great significance for the transformation product in pollution control and health effects in the photolysis of EDCs. Full article
(This article belongs to the Special Issue Transformation and Exposure Risk of Emerging Contaminants)
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